JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 20-30
RADIATION SAFETY
V.F. Demin1, V.V. Romanov2, V.Yu. Soloviev3
Harmonized Approach to the Health Safety Regulation in Different Areas of Human Activity
1. National Research Center “Kurchatov Institute”, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Federal Medical Biological Agency, Moscow, Russia; 3. Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia
Abstract
Purpose: To create harmonization approach to the development of health safety standards (HSS) in nanotechnology and other areas of human activity.
Material and methods: Main principles of health risk assessment are: principles of justification and optimization of protection; risk level limit application.
Results: Two types of harmonization are suggested: at the first stage it is necessary to overcome existing divergences and prepare scientific basis of harmonization of hygienic regulations in different areas of human activity. It makes possible to prepare basis for international harmonization of health safety standards (HSS) and other hygienic regulations.
General approach to establishing HSSs and other levels of health risk assessment using risk analysis in different areas of human activity is suggested. On the basis of this approach, universal HSSs for workers and public are suggested. Based on these universal HSSs, general HSSs and other levels of health risk assessment for different modern harm sources are proposed.
Conclusion: The approach can be the basis for harmonization of international regulations and methodological documents in the area of innovative projects’ protection in different areas of industrial and economic human activities.
Key words: risk assessment, risk index, methodology, health risk standard, harmonization, decision making principle
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 11-19
RADIATION SAFETY
M.Ph. Kiselev1, T.V. Azizova2, A.V. Akleyev3, R.M. Aleksakhin4, V.K. Ivanov5, A.N. Koterov6, I.I. Kryshev7, B.K. Lobach8, O.A. Pavlovsky9, S.A. Romanov2, A.V. Sazhin6, S.M. Shinkarev6
On the 59th Session of the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) (Vienna, 21-25 May 2012)
1. Federal Medical-Biological Agency of Russia (FMBA of Russia), Moscow; 2. Southern Urals Biophysics Institute of FMBA of Russia, Ozyorsk, Chelyabinsk Region; 3. Urals Research Center of Radiation Medicine of FMBA of Russia, Chelyabinsk; 4. Russian Institute of Agricultural Radiology and Agroecology of Russian Agricultural Academy, Obninsk; 5. Medical Radiological Research Centre of MHR, Obninsk; 6. Burnasyan Federal Medical Biophysical Center of FMBA of Russia, Moscow. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 7. Research & Production Association “Typhoon” of Roshydromet, Obninsk; 8. Nuclear Energy State Corporation “Rosatom”, Moscow; 9. Nuclear Safety Institute of RAS, Moscow.
CONTENTS
Introduction
- On the UN General Assembly resolution 66/70 (December 2011)
- Discussion of scientific reports on nine projects:
- Report R.686 “The Ability to attribute risks and effects to radiation exposure” and report R.687 “Uncertainties in risk estimates for cancer due to exposure to ionizing radiation”
- Report R.688 “Radiation exposures from electricity generation” and report R.689 “Methodology for estimating human exposures due to radioactive discharges”
- Report R.690 “Biological effects of selected internal emitters (tritium, uranium)”
- Report R.691 “Levels and effects of radiation exposure due to the nuclear accident after the 2011 great east-Japan earthquake and tsunami”
- Report R.692 “Effects of radiation exposure on children”
- Report R.693 “Epidemiology of low-dose-rate exposures of the public to natural and artificial environmental sources of radiation” and report R.694 “Mechanisms of radiation actions at low doses”
- Consideration of the Report of the UNSCEAR Secretariat
- Recommendations for future work program
- Preparation of a report of UNSCEAR to the next session of the UN General Assembly. General conclusions
Key words: risk assessment, risk index, methodology, health risk standard, harmonization, decision making principle
REFERENCES
- United Nations. UNSCEAR-2008. Report of the United Nations Scientific Committee on the Effects of Atomic Radiation. Fifty-sixth session (2008 Jul. 10-18). General Assembly Official Records Sixty-third Session. Supplement No. 46. United Nations. New York. 2008. 38 p.
- Kisielev M.Ph, Kotenko K.V., Akleev A.V. On the 59th Session of the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) (Vienna, 2008 Jul. 10-18). Medical Radiology and Radiation Safety. 2009. Vol. 54. No. 1. P. 61-75.
- United Nations. UNSCEAR 1993. Report to the General Assembly, with Scientific Annex. Annex F. Influence of dose and dose rate on stochastic effects of radiation. United Nations. New York. 1993. P. 619-727.
- United Nations. UNSCEAR 1986. Report to the General Assembly, with Scientific Annexes. Annex B. Dose - relationships for radiation-induced cancer. United Nations. New York. 1986. P. 165-262.
- United Nations. UNSCEAR 2000. Report to the General Assembly, with Scientific Annex G. Biological effects at low radiation doses. New York. 2000. P. 73-175.
- United Nations. UNSCEAR 2006. Report to the General Assembly, with Scientific Annexes. Annex C. Non-targeted and delayed effects of exposure to ionizing radiation. United Nations. New York. 2009. P. 1-79.
- International Commission on Radiological Protection. ICRP Publication 99. Low-dose Extrapolation of Radiationrelated Cancer Risk. Annals of the ICRP. Ed. by J. Valentin. Amsterdam - New-York: Elsevier. 2006. 147 p.
- International Commission on Radiological Protection. ICRP Publication 103. The 2007 Recommendations of the International Commission on Radiological Protection. Annals of the ICRP. Ed. by J. Valentin. Amsterdam - New York: Elsevier. 2007. 329 p.
- BEIR VII Report 2006. Phase 2. Health Risks from Exposure to Low Levels of Ionizing Radiation. Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation. National Research Council. [cited 2012 Jun. 20]. Available from: http://www.nap.edu/catalog/11340.html.
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 6. P. 74-77
REVIEW
A.K. Guskova
German Specialists in Soviet Atomic Project
Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
The paper is devoted to the analysis of publications on the work of German specialists in the USSR Atomic Project (1945-1956). The operations done by groups composed of different staff members are analysed. Staff members from East Germany previously involved in biophysics and dosimetry subjects were invited. The work was also elaborated by the USSR citizens who have worked in the USSR and Germany during the wartime and were sentenced to prison term thereafter. The laboratory personnel have also included voluntary hired specialists and persons with legally limited social rights (Volga river catchment residents with German origin). Main goals and tasks of work are described for four laboratories responsible for research in the areas of radioactive waste, environment releases of nuclear facilities and for studies on radiation protection of human and environment. Most active operations were done in Laboratory B (town of Sungul, Urals). Detailed information on personnel selection principles and managerial measures is provided for these comprehensively staffed teams. The work results of these teams are compared to those obtained by correspondent routinely organized laboratories and facilities in the USSR. This paper publication is related to present efforts under the program of bilateral activities between Germany and Russia.
Key words: Soviet atomic project, German specialists, collaboration history
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 5-10
RADIATION BIOLOGY
K.V. Kotenko1, I.K. Belyaev1, Yu.P. Buzulukov2, А.Yu. Bushmanov1, V.F. Demin2, I.V. Gmoshinski3, E.S. Zhorova1, V.S. Kalistratova1, N.S. Marchenkov2, P.G. Nisimov1, R.V. Raspopov3, V.Yu. Soloviev1
Experimental Research of Zinc Oxide-labeled Nanoparticles Biokinetics in Rats’ Organism after Single Oral Administration by Labeled Atoms Technology
1. Burnasyan Federal Medical Biophysical Center (FMBC) of Federal Medical Biological Agency, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Russian Research Center Kurchatov Institute, Moscow, Russia; 3. Institute of Nutrition of RAMS, Moscow, Russia
Abstract
Purpose: To make quantitative assessment of zinc oxide-labeled nanoparticles’ biokinetics in laboratory animals’ (rats’) organism after single oral administration.
Material and methods: Suspension of zinc oxide nanoparticles with 30 nmmedian diameter was used as source material. Before the injection nanoparticles were irradiated to thermal neutron beam, so that part of the atoms was activated with formation of radioactive nucleus of 65Zn with half-life of 234.8 days. Four groups of animals were used in the experiment (3 male Wistar rats with average body weight of ~ 170 g in each group). According to number of animals used in the experiment, the suspension of nanoparticles was divided into 12 parts of 0.5 mL each. Animals were sacrificed at hours 4, 24, 72 and 120 after administration; then organs of the sacrificed animals including brain, heart, lung, liver, spleen, pancreas, kidneys, testicle, also remained carcass, blood, excrement and urine were analyzed. Changes of organs’ activity were recorded on low-background gamma-ray spectrometer.
Results: Biokinetic parameters of Vistar rat-males are evaluated after single oral administration of zinc oxide nanoparticles. Maximum content of nanoparticles was observed in 24-72 hours after oral administration. 65Zn mass distribution in rats’ organs at maximum point decreases according to the following sequence: liver®kidneys®spleen ®pancreas®heart®blood®brain.
Conclusion: 1. Technology of producing new type of product - labeled nanoparticles by means of irradiating them with thermal neutrons of nuclear reactor is elaborated. 2. It is proved that there is a possibility to do research of nanoparticles’ biokinetics in the laboratory animal organisms using labeled atoms technology. 3. 65Zn activity records in the rats’ brain (near 0.06 % of administered activity) proves that nanoparticles can mount blood brain barrier.
Key words: nanoparticles, zinc oxide, radioactive label, experiment, rats, biokinetics, blood brain barrier
REFERENCES
- Soloviev V.Yu. Problem of providing safety of nanotechnology, human health products produced by means of nanotechnology and safety of life environment. Internat. Forum on Natotechnologies, 3-5.12.2008. Moscow. 2008. Vol. 2. P. 286-288.
- Hagens W.I., Oomen A.G., de Jong W.H. et. al. What do we (need to) know about the kinetic properties of nanoparticles in the body? Regul. Toxicol. Pharmacol. 2007. Vol. 49. No. 3. Р. 217-229.
- Li S.D., Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol. Pharm. 2008. Vol. 5. No. 4. Р. 496-504.
- Tang J., Xiong L., Wang S. et. al. Distribution, translocation and accumulation of silver nanoparticles in rats. J. Nanosci. Nanotechnol. 2009. Vol. 9. No. 8. Р. 4924-4932.
- De Jong W.H., Hagens W.I., Krystek P. еt. аl. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials. 2008. Vol. 29. No. 12. Р. 1912-1919.
- Zhu M.-T., Feng W.-Y., Wang Y. et. al. Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicol. Sci. 2009. Vol. 107. No. 2. Р. 342-351.
- Raspopov R.V., Buzulukov Yu.P., Marchenkov N.S. et. al. Research of zinc oxide nanoparticles’ bioavailability by radioactive tracer method. Nutrition questions. 2010. Vol. 79. No. 6. P. 14-18.
- Richness of the Nano-World. Photo-Report from the Depths of Matter. Ed. by Yu.D. Tretyakov. Moscow: BINOM. BKL Publishers. 2010. 171 p.
For citation: Kotenko KV, Belyaev IK, Buzulukov YuP, Bushmanov АYu, Demin VF, Gmoshinski IV, Zhorova ES, Kalistratova VS, Marchenkov NS, Nisimov PG, Raspopov RV, Soloviev VYu. Experimental Research of Zinc Oxide-labeled Nanoparticles Biokinetics in Rats’ Organism after Single Oral dministration by Labeled Atoms Technology. Medical Radiology and Radiation Safety. 2012;57(5):5-10.
PDF (ENG) Full-text article (in Inglish)Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 6. P. 68-73
NUCLEAR MEDICINE
T.N. Sharypova, S.L. Timerbaeva
Features of SPECT Visualization of Brain for Functional Changes Estimation in the Focal Distention Patients
Research Center of Neurology of RAMS, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Purpose:To estimate features and specific SPECT visualizations into Brodmann`s Maps in patients with cervical distention (CD).
Material and method: 16 patients with CD and 7 controls studied with SPECT (e.cam Siemens) after intravenous injection with 700 MBk 99mTc-teoxim (analog HMPAO). For analysis of results the program “Neurogam” with standardized perfusion middle maps was used.
Results: Different variants of the image cerebral perfusion by criterions hyper- or hypo-perfusion into Brodmann’s Maps have been obtained: in the group CD - increase cerebral perfusion into 1-3, 4, 6 and 40 at 81 % into right brain and 75 % into left brain; the control group - normal perfusion into 1-3, 4, 6, 5, 7, 39, 40 (U-criterion of Mann-Whitney p < 0. 001).
Conclusions: Maps of brain perfusion reflect microcirculation and functional deviations in Brodmann`s Maps 1-3, 4, 6, 5, 7, 39, 40 of CD patients in comparison with the control group.
Key words: SPECT, brain, focal dystonia, brodmann’s maps