Medical Radiology and Radiation Safety. 2018. Vol. 63. No. 5. P. 5–10

RADIATION SAFETY

DOI: 10.12737/article_5bc895f377f578.86526226

Innovative Technologies of Pre-Shift Psychophysiological Control of Personnel as Means of Increasing Safety of Radiation and Nuclear Enterprises and Objects of the State Atomic Energy Corporation ROSATOM

A.F. Bobrov¹, V.V. Ivanov², M.Yu. Kalinina³, T.M. Novikova², V.V. Ratayeva⁴, V.I. Sedin¹, V.Yu. Shcheblanov¹, E.S. Shchelkanova⁴, A.S. Samoylov¹

1. A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Central Health-Sanitary Unit № 91, Lesnoy; Murmansk region, Russia; 3. The State Atomic Energy Corporation ROSATOM, Moscow, Russia; 4. Northwest Center for Radioactive Waste Management “SevRAO”, a Branch of FSUE RosRAO, Zaozersk, Murmansk region, Russia

A.F. Bobrov – Chief Researcher, Dr. Sci. Biol., Prof.; V.V. Ivanov – Head PND, PhD Med.; M.Yu. Kalinina – Deputy Director, PhD Med.; T.M. Novikova – Medical Psychologist; V.V. Ratayeva – Specialist of Radiation and Environmental Safety; V.I. Sedin – Leading Researcher, Dr. Sci. Med., Prof.; V.Yu. Shcheblanov – Head of Lab., Dr. Sci. Biol., Prof.; E.S. Shchelkanova – Leading Specialist; A.S. Samoylov – Director General, Dr. Sci. Med., Prof. RAS

Abstract

Purpose: Validation of requirements to the hardware and software of pre-shift psychophysiological monitoring and assessment of effectiveness of use of technology of the vibraimage at pre-shift psychophysiological control of personnel of radiation and nuclear dangerous enterprises and objects of the State Atomic Energy Corporation ROSATOM.

Material and methods: Pre-shift psychophysiological control of employees of Elektrochimpribor plant (20 people) and the Northwest Center for Radioactive Waste Management “SevRAO ”, a Branch of FSUE RosRAO, Zaozersk of Murmansk region (18 workers of facilities for management of spent nuclear fuel and radioactive waste). Pre-shift psychophysiological monitoring was carried out within 3 months. During the research measurement of arterial blood pressure, assessment of health, activity and mood was taken. The psychophysiological condition was estimated according to innovative technology of the vibraimage with the use of the Vibrastaff program.

Results: Reliability improvement of a human factor is one of the main ways of improving radiation and nuclear safety of the facilities and objects of the State Atomic Energy Corporation ROSATOM. It demands improving methods and means of psychophysiological providing. First of all methods,tools and criteria of pre-shift psychophysiological control. The developed requirements to the hardware and software of pre-shift psychophysiological monitoring and innovative technology of assessment of parameters of the vibraimage allow quickly (within 1 minute) to receive the decision on the admission / not the admission to work. Its practical use gives the chance, accordingto pre-shift psychophysiological control in due time, to accept organizational, medical and other administrative decisions for improving radiation and nuclear safety of the enterprises and objects of the State Atomic Energy Corporation ROSATOM.

Key words: vibraimages, pre-shift medical examinations, pre-shift psychophysiological control, psychophysiological adaptation, psychophysiological “price” of work performance, radiation safety, human factor

REFERENCES

1. Bobrov AF, Bushmanov AYu, Sedin VI, Shcheblanov VYu. System assessment of the results of psychophysiological control. Medicine of Extreme Situations. 2015;(3):13-9. Russian.
2. Minkin VA. Vibraimage. Saint Petersburg: Renome; 2007. Russian.
3. Program for monitoring psychophysiological state of the operator of VibraStaff [Internet ]. Saint Petersburg: Multiprofile facility ELSIS; 2018 [cited 2018 Feb 1]. Available from: http://psymaker.com/downloads/VIManualRuVS.pdf. Russian.

For citation:Bobrov AF, Ivanov VV, Kalinina MYu, Novikova TM, Ratayeva VV, Sedin VI, Shcheblanov VYu, Shchelkanova  ES, Samoylov AS. Innovative Technologies of Pre-Shift Psychophysiological Control of Personnel as Means of Increasing Safety of Radiation and Nuclear Enterprises and Objects of the State Atomic Energy Corporation ROSATOM. Medical Radiology and Radiation Safety. 2018;63(5):5-10. Russian.

DOI: 10.12737/article_5bc895f377f578.86526226

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Medical Radiology and Radiation Safety. 2018. Vol. 63. No. 5. P. 19–25

RADIATION THERAPY

DOI: 10.12737/article_5bc8965ecf7302.64445070

Outcomes of Combined Treatment for Breast Cancer with Immediate Implant-Based Breast Reconstruction, Chemotherapy and Conformal Radiotherapy

E.V. Timoshkina, S.I. Tkachev, A.V. Nazarenko, O.P. Trofimova, V.V. Glebovskaya, S.M. Ivanov, T.N. Borisova

N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

E.V. Timoshkina – Radiation Oncologist; S.I. Tkachev – Leading Researcher, Dr. Sc. Med., Prof., Vice-President of RATRO; A.V. Nazarenko – Head of Dep., PhD Med.; O.P. Trofimova – Leading Researcher, Dr. Sc. Med., Prof., RATRO Member, RUSSCO Member, Russian Oncologists Association Member, ARCA Member, Member of Association of Specialists of Problem of the Melanoma, Member of Russian Oncomammologists; V.V. Glebovskaya – Senior Researcher, PhD Med.; S.M. Ivanov – Senior Researcher, PhD Med.; T.N. Borisova – Senior Researcher, PhD Med.

Abstract

Purpose: To evaluate the oncological results and late complication rate in breast cancer patients who underwent immediate implant-based breast reconstruction and adjuvant radiotherapy.

Material and methods: 32 patients with I–IIIC breast cancer after combined treatment which included immediate implant-based breast reconstruction, chemotherapy and radiotherapy, were reviewed.

Results: All 32 patients got skin erythema as an acute adverse effect. 6 (18 %) of them got acute mucositis. Median follow-up was 35 months (range 12–112 months). 2 (6 %) patients had local recurrence after 46 and 31 months since the operation day. Locoregional control rate was 94 %. 9 (28 %) patients presented distant metastases at term 8–71 months since the operation day, and metastases in bones, brain, lungs, liver and non-regional lymph nodes were diagnosed. 2 (6 %) patients died because of disease progression.

Late adverse effects of skin and soft tissue in irradiated area were found in 4 (13 %) patients – capsular contracture was diagnosed 1 (n = 1), 2 (n = 2) and 3 (n = 1) stages. In two cases of four, capsular contracture was asymptomatic and found during the second stage of breast reconstruction while changing tissue expander to implant. Capsulotomy was performed, and aesthetic effect was good. In one case capsular contracture was the reason of implant removal, and then second reconstruction using tissue expander was performed.

Conclusion: Nowadays immediate implant-based breast reconstruction is an essential part of combined treatment. Breast cancer patients after immediate implant-based breast reconstruction can be treated in adequate manner, and breast reconstruction is not a contraindication for radiotherapy. Low complication rates can still be acquired with the use of state-of-art 3D and 4D radiotherapy techniques and supportive care.

Key words: breast cancer, breast reconstruction, tissue expander, radiotherapy, late complications

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10. Carnevale A, Scaringi C, Scalabrino G, Campanella B, Osti MF, De Sanctis V, et al. Radiation therapy after breast reconstruction: outcomes, complications and patient satisfaction. Radiol Med. 2013 Oct;118(7):1240-50.
11. Piroth MM, Piroth DM, Pinkawa M, Woodruff SG, Holy R, Eble MJ. Immediate Reconstruction with an Expander/Implant Following Ablatio Mammae because of Breast Cancer: Side Effects and Cosmetic Results after Adjuvant Chest Wall Radiotherapy. Strahlentherapie und Onkologie. 2009 Oct;185(10):669-74
12. Wagner RM, Spzunar SM, Stefani WA, Williams JL, Edhayan E, Dul CL, et al. Radiation and depression associated with complications of tissue expander reconstruction. [abstract]. In Proceedings of the Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2015 Dec 8-12; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res. 2016;76(4 Suppl):Abstract nr P2-13-02.
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For citation:Timoshkina EV, Tkachev SI, Nazarenko AV, Trofimova OP, Glebovskaya VV, Ivanov SM, Borisova TN. Outcomes of Combined Treatment for Breast Cancer with Immediate Implant-Based Breast Reconstruction, Chemotherapy and Conformal Radiotherapy. Medical Radiology and Radiation Safety. 2018;63(5):19-25.Russian.

DOI: 10.12737/article_5bc8965ecf7302.64445070

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Medical Radiology and Radiation Safety. 2018. Vol. 63. No. 5. P. 11–18

RADIATION MEDICINE

DOI: 10.12737/article_5bc8960ba308e0.31051556

Psychophysiological Adaptation of Patients with Local Radiation Injuries

N.A. Metlyaeva, A.Yu. Bushmanov, V.I. Krasnuk, A.A. Davtyan, O.V. Shcherbatykh, L.A. Yunanova, V.V. Koren’kov, D.S. Yunanov

A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

N.A. Metlyaeva – Leading Researcher, Dr. Sc. Med.; A.Yu. Bushmanov – Senior Vice-President, Dr. Sc. Med., Prof.; V.I. Krasnuk – Head of Department No. 2, Dr. Sc. Med.; A.A. Davtyan – Head of Department of Acute Radiation Pathology (hematological), PhD Med.; O.V. Shcherbatykh – Junior Researcher; L.A. Yunanova – Engineer; V.V. Koren’kov – Head of Special Admission Office, PhD Med.; D.S. Yunanov – Engineer

Abstract

Purpose: Assessment of psycho-physiological adaptation of patients with local radiation injuries (LRI), depending on the presence or absence of an established connection with an accident at work in connection with a radiation accident or an incident that has undergone a psychophysiological examination.

Material and methods: Clinical and psychophysiological examination of 57 patients with local radiation injuries was performed, 20 of them, whose LRI s were associated with an accident at work (Group 1) and 37 patients, whose LRI connection was not established with production (Group 2). The mean age of the examined subjects was 41.6 ± 3.1 and 52.0 ± 1.6 years. The psychophysiological examination was carried out using the automated program-methodical complex “Expert”, designed to study the personality of a person, the cognitive and intellectual characteristics of a person using the method of the Multilateral Personality Study is an adaptation of MMPI, the method of Cattell’s 16PF, the Raven test, simple and complex sensorimotor reactions and reaction to a moving object.

Results: Clinical and psychophysiological assessment of personality and the actual mental state of patients with LRI having an established connection to an accident at work in comparison with patients with LRI with an unrelated connection with production allowed to determine the main types of disturbance of psychophysiological adaptation in a kind of anxiety-hypochondriacal type of adaptation disorder with a tendency to dissocial behavior in patients with LRI who have an established connection with an accident at work.

Conclusion: Anxiety-hypochondriacal type of disturbance of psychophysiological adaptation in patients with LRI is caused primarily by concern about the state of physical health, which determined the tension of mental adaptation with a tendency to neglect social norms and rules of behavior, with a tendency to dissocial behavior, psychasthenia, autization, distancing, alienation, affective rigidity, the desire to put the blame on others for the violation of interpersonal relationships, life difficulties and emotions conflicts. The dissocial type of the disturbance of psychophysiological adaptation was revealed mainly in patients with LRI who have established connection with an accident at work.

Key words: local radiation injuries, acute radiation syndrome, psyhaphysiological adaptation, radiation risk

REFERENCES

1. Petushkov VN. Development and course of local radiation injury of tissues. Acute radiation syndrome in humans. Ed. Kurshakova NA. Moscow: Medicine; 1965. 314 p. Russian.
2. Orlov VM, Petushkov VN, Sych LI. Acute radiation syndrome of hands. Medical Radiology. 1970;15(1):53-6. Russian.
3. Barabanova AV, Nadezhina NM. Clinical picture of local radiation lesions. Radiation Medicine. P. 15 Radiation damage to humans Moscow. Publishing house. 2001;2:161-85. Russian.
4. Berezin FB, Miroshnikov MP, Sokolova ED. Method of multilateral study of personality. Structure, basis of interpretation, some areas of application. 3 edition, amended and updated. Moscow: Publishing House «BEREZIN FELIX BORISOVICH»; 2011. 320 p. Russian.

For citation: Metlyaeva NA, Bushmanov AYu, Krasnuk VI, Davtyan AA, Shcherbatykh OV, Yunanova LA, Koren’kov VV, Yunanov DS. Psychophysiological Adaptation of Patients with Local Radiation Injuries. Medical Radiology and Radiation Safety. 2018;63(5):11-8. Russian.

DOI: 10.12737/article_5bc8960ba308e0.31051556

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Medical Radiology and Radiation Safety. 2018. Vol. 63. No. 5. P. 26 –32

NUCLEAR MEDICINE

DOI: 10.12737/article_5bc8968bb9d9a3.36167944

SPECT/CT in the Assessment of the Jaw Autograft Viability

A.D. Ryzhkov¹, L.P. Yakovleva¹, A.S. Krylov¹, S.V. Shiryaev¹, M.A. Kropotov², V.A. Sobolevsky¹, Yu.Yu. Dikov¹, R.B. Azimova¹, V.Yu. Ivashkov¹

1. N.N. Blokhin Medical Research Center of Oncology. Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. A.S. Loginov Moscow Clinical Scientific Center. Moscow, Russia

A.D. Ryzhkov – Leading Researcher, Dr. Sc. Med.; L.P. Yakovleva – Head of the Dep., PhD Med, Member of RUSSCO, Member of the Russian Association of Endocrine Surgeons, Member of the Society of Specialists in the Treatment of Head and Neck Tumors; A.S. Krylov – Radiologist, PhD Med., Member of the European Association of Nuclear Medicine and Molecular Imaging (EANMMI); S.V. Shiryaev – Head of Lab., Dr. Sc. Med., President of the OSMI, Member of EANMMI, Member of ACNMMI, Member of SNMMI; M.A. Kropotov – Leading Researcher, Dr. Sc. Med., Head of Dep., Member of RUSSCO, Member of the Russian Association of Endocrine Surgeons, Member of the Society of Specialists in the Treatment of Head and Neck Tumors; V.A. Sobolevsky – Head of Dep., Dr. Sc. Med.; Yu.Yu. Dikov – Research Worker, PhD Med.; R.B. Azimova – Research Worker, PhD Med.; V.Yu. Ivashkov – Research Worker

Abstract

Purpose: To evaluate the effectiveness of SPECT/CT for the assessment of graft viability following revascularized bone grafts in patients with mandibular (18) and maxilla (1) reconstruction.

Material and methods: We investigated 19 patients with revascularized grafts from the fibula (16 patients), iliac crest (2 patients) and shoulder blade graft (1). For the follow up of all these patients, 99mTc-MDP bone scintigraphy and SPECT/CT was performed between 4–5 days postoperatively. The evaluation of the grafts was based on a comparison of tracer uptake between graft and the cranium.

Results: 17 of 19 grafts had an uncomplicated clinical course. Complications in the graft occurred in two patients. In the analysis of planar scintigrams with uncomplicated healing were showed correct assessment in 10 of 17 patients and in 1of 2 patients with signs of necrosis of graft fragments. SPECT/CT was performed in addition to planar imaging.

The increased uptake grafts were showed with SPECT/CT in all patients with uncomplicated clinical course. In the failed 2 grafts, decreased uptake was observed in both patients. In the analysis of SPECT/CT images the correct results were showed in all clinical cases.

Conclusion: SPECT/CT performed within 6 days after the mandibular reconstruction is a useful tool to monitor the viability and early complications of revascularized mandibular and maxilla bone grafts. SPECT/CT is also recommended to interpretation of the bone scans and to precise assessment of graft viability.

Key words: maxilla and mandible reconstruction, autograft viability, bone scintigraphy, SPECT/CT

REFERENCES

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For citation: Ryzhkov AD, Yakovleva LP, Krylov AS, Shiryaev SV, Kropotov MA, Sobolevsky VA, Dikov YuYu, Azimova RB, Ivashkov VYu. SPECT/CT in the Assessment of the Jaw Autograft Viability. Medical Radiology and Radiation Safety. 2018;63(5):26-32. Russian.

DOI: 10.12737/article_5bc8968bb9d9a3.36167944

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