JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 62-68

RADIATION THERAPY

O.P. Trofimova, S.I. Tkachev, Z.P. Mikhina, Yu.I. Pryamikova, N.P. Shipilina, O.S. Zaichenko, I.V. Kolyadina, A.M. Malishev

The Addition of a Boost Dose on the Primary Tumor Bed after Breast Conserving Treatment for Breast Cancer Patients

N.N. Blokhin Russian Cancer Research Center of RAMS, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To increase the radiation therapy efficacy in breast cancer patients.

Material and methods: Investigation includes 438 patients with verified breast cancer. All patients received breast conserving treatment within period of 2000–2012, including breast conserving surgery ± systemic therapy – 58 pt.; breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) – 313 pt.; breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) + boost dose on the primary tumor bed (10–16 Gy) – 72 pt.

Results: Local relapse after breast conserving surgery ± systemic therapy – 24.5 %; after breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) – 5.8 % (p < 0.05); after breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) + boost dose on the primary tumor bed (10–16 Gy) – 2.7 %.

Conclusion: The addition of a boost dose on the primary tumor bed after breast conserving treatment for breast cancer patients decrease local recurrences.

Key words: radiotherapy, breast cancer, local recurrens

Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 53-61

RADIATION THERAPY

L.I. Musabaeva1, V.A. Lisin1,2, Zh.A. Startseva1, O.V. Gribova1, V.V. Velikaya1, A.A. Melnikov1

Neutron Therapy on U-120 Cyclotron

1. Cancer Research Institute, Siberian Branch of the RAMS, Tomsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. National Research Tomsk Polytechnic University

ABSTRACT

The review is devoted to the 30-year neutron therapy experience in cancer treatment at the Tomsk Cancer Research Institute. In 1983, the Institute of Nuclear Physics affiliated to the Tomsk Polytechnic University was the first in Russia to perform radiation therapy with fast neutrons for cancer patients. Neutron therapy at the initial stage included the formation of the therapeutic fast neutron beam with the average energy of 6.3 MeV, dosimetric and radiobiological studies, clinical trials and accumulation of the own experience in the treatment of resistant tumors with fast neutrons. Efficacy of new methods of neutron and concurrent neutron-photon therapy, optimal regimens of combined modality treatment and independent radiation therapy were studied. The comprehensive programme on the prevention and treatment of acute radiation-induced complications and radiation damages to normal tissues and critical organs was developed.

Content

Introduction

Purpose of the study

Dosimetric and radiobiological studies

Clinical trials

Patterns of tumor reoxygenation in fast neutron therapy

Parotid salivary gland

Thyroid cancer

Neutron therapy for patients with locally advanced T2–4N0–2M0 breast cancer

Pathological tumor response to preoperative neutron therapy

Fast neutrons in the treatment of locally recurrent breast cancer

Cytogenetic studies in cancer patients who received neutron therapy

Conclusion

Key words: therapeutic channel, resistant tumor forms, neutron Therapy

Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 39-45

RADIATION MEDICINE

N.A. Isaeva, F.S. Torubarov, Z.F. Zvereva

Estimation of Risk of Vascular Diseases of the Workers Brain of the Bilibinskaya Nuclear Power Station

Burnasyan Federal Medical Biophysical Center of the FMBA of Russia, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: Revealing a group of persons with the raised risk of ischemic stroke by the method of screening analysis.

Material and methods: In this research 426 (161 woman and 265 men) workers of the Bilibinsky nuclear power station took part. In the professional aspect the studied contingent is presented as by both operation personnel (heads, operators, process engineers, etc.), i.e. persons mainly carrying out brainwork, and technicians (electromechanics, electrical engineers, mechanics, welders, electric welders, etc.), i.e. persons mainly carrying out manual labor. All surveyed have being exposed to small doses of ionizing radiation within permissible values and subjected to psycho-emotional pressure. In this work the screening analysis system with the use of 5-factorsFramingemsky scale was applied.

Results: It was found that 141 persons of 426 (33. 1%) had the raised risk of ischemic stroke. The most subjected to the risk of ischemic stroke was the 45–49 age group Arterial pressure and smoking were dominating risk factors. Hypercholesternaemia was the least significant risk factor in all age groups, both men and women. According to medical out-patient cards, in the group of raised risk (141 persons) only two had the cerebral vascular diseases diagnosis. 91 people have 1–2 degree arterial hypertension, the rest 48 persons did not have any diseases leading to vascular pathology of the brain or were practically healthy. This publication is the first in a series of articles on comparative risk estimation of brain vascular diseases of personnel of the nuclear power stations located in various regions of the Russian Federation.

Key words: brain, vascular diseases, screening analysis, risk factors, personnel, Bilibinskaya nuclear power station, ionizing radiation

Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 46-52

DIAGNOSTIC RADIOLODGY

A.A. Levitov, V.I. Krasnyuk, E.V. Sitnikova, A.P. Dunaev

The Effectiveness of X-ray Linear Digital Tomosynthesis in Visualization of Focal Lesions in Lungs, Suspected Metastases, Comparing With Digital Radiography in Patients with Breast Cancer

Burnasyan Federal Medical Biophysical Center of the FMBA of Russia, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: Comparison of the effectiveness of the Χ-ray digital linear tomosynthesis and digital Χ-ray in visualization of focal lesions in the lung, suspicious for metastasis in patients with verified by histology breast cancer.

Material and methods: Radiographic studies were performed in 47 patients with verified by histology breast cancer of different stages using two Χ-ray methods: digital radiography and digital linear tomosynthesis.

Results: Focal lesions in the lung suspicious for metastasis were identified with digital radiography of the chest in 8.5 % of surveyed patients only; against 29.8 % – with the use of digital linear tomosynthesis. Conclusion: Considering the data obtained in the course of our study, it is advisable to use a digital linear tomosynthesis as a more effective Χ-ray method for the focal lung lesions’ verification in patients with breast cancer.

Key words: linear digital tomosynthesis, digital radiography, lung metastases, breast cancer

Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 30-38

RADIATION MEDICINE

N.A. Metlyaeva

Features of Social and Psychophysiological Adaptation of Three Patients Survived Acute Radiation Disease III and IV degree of Severity Complicated with Skin Radiation Injury Resulted from Chernobyl NPP Accident

Burnasyan Federal Medical Biophysical Center of the FMBA of Russia, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To evaluate the social and psychophysiological adaptation of three patients, survived acute radiation disease (ARD) 25 years ago.

Material and methods: Three patients were irradiated with gamma–beta radiation in time of Chernobyl NPP accident with estimated by cytogenetic methods total doses: 3,5 Gy, 4.3 Gy and 9.8 Gy. They were observed with using the automated program and methodical Expert complex intended for research of personal properties of the person, cognitive and intellectual features of the personality. Two of them suffered with ARD of the III degree severity and the third one suffered with ARD of IV degree. Also they had multiple skin beta radiation injuries.

Conclusion: Psychophysiological research of the 25 years follow-up study of three patients survived ARD of severe (III) and very severe (IY) degree resulted from Chernobyl nuclear accident shows that average profile of multilateral research of the third patient (ARD IV, dose 9.8 Gy) personality exceed borders of population statistical norm (<70>30) on a scale of T-points and testify to overstrain of mental adaptation. The same data were received for the second patient (ARD III, dose 4.3 Gy). Average profile of multilateral research of the personality of the patient (ARD III, dose 3.5 Gy) registered in borders of population statistical norm. That last patient had less significant skin radiation injuries.

strong>Key words: acute radiation disease, ionizing radiation, Chernobyl accident, local radiation injuries, adaptation, clinical case

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