Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 5–10 

Influence of Powerful Non-Ionizing Terahertz Radiation 

on Healthy and Tumor Human Cells of Neural Origin

R.O. Shatalova¹, S.A. Gurova¹, V.A. Revkova², I.V. Ilina³, D.S. Sitnikov³ 

¹National Research Nuclear University, MEPhi Obninsk Institute for Nuclear Power Engineering, Obninsk, Russia

²Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies, Moscow, Russia

³Joint Institute for High Temperatures, Moscow, Russia

Contact person: Dmitry Sergeevich Sitnikov: This email address is being protected from spambots. You need JavaScript enabled to view it.  

ABSTRACT 

Purpose: Study of the influence of high-power pulses of coherent non-ionizing terahertz (THz) radiation on the formation of foci of double-strand DNA breaks and the proliferative activity of human neuronal cells.

Material and methods: Irradiated cell cultures are direct reprogramming neural progenitor cells (drNPCs), neuroblastoma cells (SK-N-BE). Cells are irradiated with a sequence of THz radiation pulses with a peak intensity of ~ 20 GW/cm2 and electric field strength of 2.8 MV/cm. Irradiation lasts 30 mins.

Results: There is no statistically significant difference in the number of γH2AX histone foci between experimental and control cell groups.

Conclusion: It was shown that a short exposure (30 min) of cells to THz radiation with intensity of 20 GW/cm2 does not affect the proliferative activity of both neural progenitor cells and neuroblastoma cells and does not cause a significant increase in γH2AX foci in any of the studied cell lines. 

Key words: non-ionizing radiation, terahertz radiation, H2AX histone foci, proliferative activity, neural stem cells, SK-N-BE neuroblastoma

For citation: Shatalova RO, Gurova SA, Revkova VA, Ilina IV, Sitnikov DS. Influence of Powerful Non-Ionizing Terahertz Radiation on Healthy and Tumor Human Cells of Neural Origin. Medical Radiology and Radiation Safety. 2021;66(5):5–10.

 DOI: 10.12737/1024-6177-2021-66-5-5-10

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The authors declare no conflict of interest.

Financing. The studies were carried out using the UNU "Laser terawatt femtosecond complex", which is part of the Center for Collective Use "Laser femtosecond complex" of the Joint Institute for High Temperatures of the Russian Academy of Sciences with the financial support of the Russian Foundation for Basic Research within the framework of scientific project No. 19-02-00762.

Contribution. Development of the research concept and assembly of the experimental scheme - D. Sitnikov;

development of research design, work with cell culture, study of THz exposure - Revkova VA;

conducting experiments on irradiation of cells - Sitnikov D.S., Ilyina I.V., Gurova S.A., Shatalova R.O.,

statistical data processing - Gurova S.A., Shatalova R.O.,

writing and scientific editing of text - all authors.

Article received: 16.03.2021. 

Accepted for publication: 21.04.2021.  

Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 18–22

The Ratio of the Extraversion and Fluid Intelligence Levels as a Predictor of the Operators’ Successful Professional Activity 

A.A. Kosenkov

A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia

Contact person: Aleksandr Kosenkov: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Results: To study the relationship between the ratio of the extraversion and fluid intelligence levels with the success of the professional activity of the nuclear power plants (NPP) operators.

Material and methods: This paper analyzes the results of psychodiagnostic examinations of operators of main control rooms of NPPs that functioned under normal conditions. All individuals were administered the J. Raven's “Progressive matrices”, the Russian language adaptation of the Minnesota Multiphasic Personality Inventory (MMPI) and the Sixteen Personality Factor Questionnaire (16PF, form A). Cross-peer review using the ranking method identified 5 groups of operators with different levels of professional success (from markedly reduced to high).

Results: Using factor analysis, the dimension of the data matrix obtained during the surveys was reduced. Correlation analysis showed that out of 9 identified factors, only 2 had a statistically significant correlation with the success of professional activity, namely, the factors of extraversion (negative relationship) and intelligence (positive relationship). Based on these two factors, an automatic classification of operators was carried out using cluster analysis, as a result of which 5 classes of operators were identified. It was shown that classes A and B with a predominance of the extraversion factor included mainly (79 %) operators with a level of professional success below average. On the contrary, classes C, D and E with a predominance of the intelligence factor consisted mainly (81 %) of operators with average and above average levels of professional success. It is noteworthy that the average value of intelligence factor in one of the classes consisting of operators, advantageously with lower professional success rate (class B) was the same or even 10 T-scores higher in comparison with the classes represented mainly by operators whose success rate was assessed from medium to high.

Conclusion: Factors of extraversion and intelligence are associated with the quality of performance of professional duties by the NPP control room operators under normal operating conditions. At the same time, the success of their professional activity depends not so much on the quantitative values for these factors, but on their ratio, namely: the predominance of the intelligence factor is prognostically favorable.

Key words: nuclear power plant, operators, main control room, extraversion, intelligence, success of professional activity, 

psychological professional selection

For citation: Kosenkov AA. The Ratio of the Extraversion and Fluid Intelligence Levels as a Predictor of the Operators’ Successful Professional Activity. Medical Radiology and Radiation Safety 2021;66(5):18-22.

DOI: 10.12737/1024-6177-2021-66-5-18-22

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The author declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared by one author

Article received: 23.12.2020. 

Accepted for publication: 20.01.2021. 

Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 11–17

On the Dose Coefficient of Uranium Hexafluoride

S.P. Babenko¹, A.V. Bad'in²

¹N.E. Bauman Moscow State Technical University, Moscow, Russia

²Department of Physics, M.V. Lomonosov Moscow State University, Moscow, Russia

Contact person: Andrey Valentinovich Bad’in: This email address is being protected from spambots. You need JavaScript enabled to view it.  

ABSTRACT

Introduction: Uranium hexafluoride (UF6, UHF) is a gaseous product containing uranium and fluorine. Once in the air, it interacts with water vapor and produces hydrolysis products that can penetrate the human body and lead to the chemical effects of uranium and fluorine, as well as the radiation effects of uranium on the body. This action can be very strong and therefore serious attention has been paid to its study for a long time.

Purpose: Quantitative calculation of the radiation effects of uranium on humans and their analysis in the conditions of daily work at nuclear power plants, as well as in emergency situations.

Material and methods: We consider uranium hexafluoride that appears under certain conditions in the air of the working rooms of some enterprises and describes methods for describing the distribution of UHF hydrolysis products to objects that can sense their effects. All these methods are combined into a single integrated model. The analytical expressions obtained in the framework of this model at various stages are given, which make it possible to calculate the radiation effect of UHF.

Results: The calculated values of the characteristics of the radiation exposure are given, their analysis is carried out. The conditions are formulated under which there is a danger of serious radiation exposure of uranium hexafluoride to employees of nuclear power plants during everyday work and in emergency situations.

Conclusion: Based on all the material presented, it is concluded that the constructed mathematical model reliably describes the event in question and allows us to calculate the radiation effect of uranium on humans.

Key words: uranium hexafluoride, hydrolysis products, inhalation intake, percutaneous intake, mathematical model

For citation: Babenko SP, Bad'in AV. On the Dose Coefficient of Uranium Hexafluoride. Medical Radiology and Radiation Safety. 2021;66(5):11–17.

DOI: 10.12737/1024-6177-2021-66-5-11-17

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 16.03.2021. 

Accepted for publication: 21.04.2021.

Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 23–32

Radiation-Hygienic Investigations of Experimental Production of Mixed Nitride Uranium-Plutonium Fuel at JSC SChC. Part 1: Methods and Results

L.A. Ilin ¹, A.S. Samoylov ¹, A.G.Tsovyanov ¹, S.M. Shinkarev ¹, N.K. Shandala ¹, P.P. Gantsovsky ¹, A.E. Karev ¹, B.A. Kukhta ¹, A.V. Simakov ¹, V.N. Klochkov ¹,  I.P. Korenkov¹, A.M. Lyaginskaya ¹, O.V. Parinov ¹, V.M. Solomatin ², K.M. Izmestyev ³

¹SRC FMBC of FMBA, Moscow, Russia

²JSC Proryv, Moscow, Russia

³JSC Siberian Chemical Combine, Seversk, Russia

Contact person: Alexander Georgievich Tsovyanov: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To present the methods and results of studies of the factors of radiation exposure to workers involved in the manufacture of mixed uranium-plutonium nitride (MUPN) fuel at the complex experimental installations CEI-1 and CEI-2 of JSC SChC.

Material and Methods: Regularities of the formation of external exposure doses have been revealed based on the study of the dynamics of the ambient dose equivalent rate (ADER) of photon and neutron radiation at the CEI-1 and CEI-2 workplaces, as well as instrumental individual dosimetric control of the equivalent doses to workers. In order to assess the inhalation intake and possible doses from internal irradiation, studies of the physicochemical properties of radioactive aerosols were carried out.

Results: It has been found that the main sources of penetrating radiation in the premises of CEI-1 are boxes where tablets are pressed, chips and rejected tablets are crushed, as well as temporary storage of products is occurred. The highest ADER values have been measured in those boxes, where the radiation exposure was due to radioactive contamination caused by past activity, and is not associated with fabrication of MUPN fuel. A significant contribution of neutron exposure to individual doses of workers was measured, which exceeded the contribution of gamma exposure at some workplaces of the CEI-1. At CEI-2, a non-functioning exhaust ventilation pipe passing over the premises was found to be a powerful source of external radiation. This pipe contained a significant amount of radioactive material. Assessment of the contribution of gamma exposure from the ventilation pipe to the external exposure of workers reached 85% at some workplaces. Studies of the physicochemical properties of radioactive aerosols have revealed a high reactivity of MUPN compounds, leading to instant oxidation of the thoracic fraction of MUPN fuel aerosols under contact with air. The complex morphological and dispersed composition of aerosol particles in combination with a complex chemical composition caused by the aging processes of aerosols, can lead to a fundamental difference in the biokinetics of MUPN aerosols, the process of dose formation and, consequently, the degree of radiological hazard compared to those adopted in the ICRP models for U and Pu.

The results of the current radiation-hygienic research are of a preliminary nature, since the object of this research is an experimental installation, which was used to develop a new technology for the production of MUPN fuel. The instrumental and methodological approaches to assess the factors of radiation exposure to workers tested at these experimental installations, will be used in the future to conduct similar studies during the pilot industrial operation of new modules for fabricating and refurbishing of MUPN fuel.

Key words: mixed nitride uranium-plutonium fuel, radiation safety, complex experimental installation, gamma and neutron exposure, radioactive aerosols

For citation: Ilin LA, Samoylov AS., Tsovyanov AG, Shinkarev SM, Shandala NK, Gantsovsky PP, Karev AE, Kukhta BA, Simakov AV, Klochkov VN, Korenkov IP, Lyaginskaya AM, Parinov OV, Solomatin VM, Izmestyev KM. Radiation-Hygienic Investigations оf Experimental Production оf Mixed Nitride Uranium-Plutonium Fuel at JSC Schc. Part 1: Methods and Results. Medical Radiology and Radiation Safety. 2021;66(5):76-86.

DOI: 10.12737/1024-6177-2021-66-5-23-32

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Contribution. Article was prepared with equal participation of the authors.

Article received: 23.12.2020. 

Accepted for publication: 20.01.2021.