JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4

Risk Factors for Arterial Hypertension (Literature Review)

K.V. Briks

Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia

Contact person: K.V. Briks, This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

The review provides up-to-date data on effects of non-modifiable (sex, age) and modifiable (smoking, alcohol consumption, obesity, vitamin D deficiency, marital status, physical activity, depression) non-radiation risk factors on incidence risks of arterial hypertension. The review also refers to scientific evidence of the impact of ionizing radiation on arterial hypertension.

Keywords: arterial hypertension, ionizing radiation, risk factors, relative risk, odds ratio, excess relative risk

For citation: Briks KV. Risk Factors for Arterial Hypertension (Literature Review). Medical Radiology and Radiation Safety. 2022;67(4):24-35. DOI: 10.33266/1024-6177-2022-67-4-24-35

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The author declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors

Article received: 15.03.2022.  Accepted for publication: 23.04.2022

 

 

 

Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4

Incidence and Mortality from Central Nervous System Tumors
in the Cohort of Workers Chronically Exposed to Radiation

M.B. Moseeva, T.V. Azizova, M.V. Bannikova

Southern Urals Biophysics Institute of the Federal Medical Biological Agency, Ozyorsk, Russia.

Contact person: Azizova Tamara Vasilievna, This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To analyze incidence and mortality rates of central nervous system (CNS) primary tumors (PT) in the cohort of workers chronically exposed to radiation. 

Material and methods: Study cohort included 22237 Mayak Production Association workers. Work history data and dose estimates from the “Mayak Worker Dosimetry System 2013” were used. Clinical and epidemiology data were obtained from the “Clinic” database. Crude and age-adjusted (by indirect method) incidence and mortality rates for CNS PT per 100000 person-years were calculated. Standardized incidence and mortality trends were analyzed by Jointpoint 4.0.4.

Results: 53 cases and 47 deaths from malignant neoplasms (MN) of brain and spinal cord, cerebral nerve and other parts of CNS (C70–C72 ICD-10 codes) as well as 40 cases and 7 deaths from non-malignant neoplasms (NMN) of brain and other parts of CNS (D-33 ICD-10 code) were identified. CNS MN were more frequent among males (83 %), and CNS NMN were more frequent among females (55 %). Both CNS MN and NMN developed at younger ages among males as compared with females, CNS PT frequency increased with increased attained age. Analysis in relation to calendar period revealed the increasing trend for CNS PT incidence among females only (р=0,008). Effects of chronic occupational radiation exposure on CNS PT incidence and mortality rates were not established either among males or females.

Conclusion: Findings should be considered as preliminary and require further studies.

Keywords: workers, chronic radiation exposure, central nervous system, primary tumors, malignant neoplasms, non-malignant neoplasms

For citation: Moseeva MB, Azizova TV, Bannikova MV. Incidence and Mortality from Central Nervous System Tumors in the Cohort of Workers Chronically Exposed to Radiation. Medical Radiology and Radiation Safety. 2022;67(4):42-48. DOI: 10.33266/1024-6177-2022-67-4-42-48

References

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 15.03.2022.  Accepted for publication: 11.05.2022

 

 

 

Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4

X-ray Estimation of Structural-topographic Parameters of the Tempo-low Jaund
Joint After Orthognic Surgical Treatment of Dental Jaws with Condition

M.A. Mokhirev, O.S. Kaganova, V.N. Olesova, V.I. Ermolin, E.E. Olesov, A.A. Ilyin

A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia.

Contact person: Olesova Valentina Nikolaevna, This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: Using the methods of radiation diagnostics, to trace in dynamics the structural and topographic state of the temporomandibular joint (TMJ) before and after orthognathic treatment of patients with air conditioning

Material and Methods: A CT analysis of the TMJ condition was carried out before and after orthodontic surgical removal of the dentofacial anomaly (skeletal form) with the effects of Candyline resorption. We used the method of Fadeev R.A. et al. to assess the TMJ parameters: height of the head of the lower jaw; anterior and posterior articular angle; the width of the joint space in the upper, anterior, posterior, mesial and lateral sections; maximum width of the head of the lower jaw; density of cortical and cancellous bones of the head of the lower jaw; height of the articular fossa; the length of the anterior slope of the articular fossa; angle of the anterior slope of the articular fossa; the length of the posterior slope of the articular fossa; angle of the posterior slope of the articular fossa.

Results: Comparison of CT parameters of TMJ before and after orthognathic treatment reveals a positive trend in remodeling of the articular process of the lower jaw after surgery, as evidenced by a noticeable increase in the width of the head of the lower jaw with a slight decrease in its height. The absence of compression in the bilaminar zone of the TMJ is recorded due to an increase in the width of the joint space in the posterior section, although the width of the joint space in the upper and anterior sections still does not correspond to normal values. The preservation of a lower density of the cortical and spongy layers of the articular head in comparison with the norm is apparently associated with continued adaptation to the new position of the articular processes and changed functional loads.

Conclusion: A comprehensive orthodontic and surgical approach to the elimination of dentoalveolar anomalies is effective and can be recommended in the treatment of patients with skeletal anomalies and condyloresorption, as it provides not only a significant improvement in facial aesthetic parameters, but also has a positive effect on the structural and topographic parameters of the temporomandibular joint.

Keywords: maxillofacial anomaly, temporomandibular joint, orthognathic surgery, computed tomography, condition dynamics

For citation: Mokhirev MA, Kaganova OS, Olesova VN, Ermolin VI, Olesov EE, Ilyin AA. X-ray Estimation of Structural-topographic Parameters of the Tempo-low Jaund Joint After Orthognic Surgical Treatment of Dental Jaws with Condition. Medical Radiology and Radiation Safety. 2022;67(4):57-61. DOI: 10.33266/1024-6177-2022-67-4-57-61

References

1. Shipika D.V. Sovershenstvovaniye Diagnostiki i Lecheniya Zabolevaniy VNCHS u Patsiyentov s Anomaliyami Prikusa = Improving the Diagnosis and Treatment of TMJ Diseases in Patients with Malocclusion. Extended abstract of candidate’s thesis in Medicine. Moscow Publ., 2012. 26 p. (In Russ.).

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5. Anuna Laila Mathew, Amar A. Sholapurkar, and Keerthilatha M. Pai Condylar Changes and Its Association with Age, TMD, and Dentition Status: A Cross-Sectional Study. Int. J. Dent. 2011:1-7.

6. Fadeev R.A., Zotova N.Yu., Kuzakova A.V. Method for Examining the Temporomandibular Joints Using Dental Computed Tomography. Institut Stomatologii = The Dental Institute. 2011;4:34-36 (In Russ.).

 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The author declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors

Article received: 20.04.2022.  Accepted for publication: 25.05.2022

 

 

 

Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4

Magnetic Resonance Imaging of Primary Extra-Axial Intracranial Tumors:
Diagnostic Problems and Prospects of Radiomics

А.V. Kapishnikov1, E.N. Surovcev1,2, Yu.D. Udalov3

1Samara State Medical University, Samara, Russia.

2Treatment and Diagnostic Center of the International Institute of Biological Systems named after Sergey Berezin, Tolyatti, Russia.

3Federal Scientific Clinical Center for Medical Radiology and Oncology, Dimitrovgrad, Russia.

Contact person: Kapishnikov Aleksandr Viktorovich: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

CONTENTS

Introduction

MRI semiotics in the differential diagnosis of primary extra-axial intracranial tumors (PEIT)

Localization of the tumor and its relationship with the anatomical structures

Heterogeneity (heterogeneity) of the tumor

Tumor margins and peritumoral edema

Apparent diffusion coefficient (ADC)

Dural tail sign

Information technology for MRI analysis and radiomics

Radiomics in differential diagnosis of PEIT

Conclusion

Keywords: magnetic resonance imaging, primary extra-axial intracranial tumors, meningiomas, radiomics, information technology.

For citation: Kapishnikov АV, Surovcev EN, Udalov YuD. Magnetic Resonance Imaging of Primary Extra-Axial Intracranial Tumors: Diagnostic Problems and Prospects of Radiomics. Medical Radiology and Radiation Safety. 2022;67(4):49-56. DOI: 10.33266/1024-6177-2022-67-4-49-56

References

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The author declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors

Article received: 20.04.2022.  Accepted for publication: 25.05.2022

 

 

Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4

Three-Color FISH Method: Translocations in Peripheral Blood Lymphocytes Cultures before and after Local Gamma Radiation for Breast Cancer

V.Yu. Nugis, T.A. Astrelina, V.A. Nikitina, M.G. Kozlova,
I.V. Kobzeva, E.E. Lomonosova, Yu.B. Suchkova,
D.Yu. Usupzhanova, V.A. Brunchukov,  A.A. Rastorgueva,
T.F. Malivanova, V.A. Brumberg,T.V. Karaseva, E.S. Lyubaeva,
D.Yu. Bobrov, N.G. Stepanyants, M.Yu. Sukhova, A.S. Samoilov

A.I. Burnasyan Federal Medical Biophysical Center of FMBA of Russia, Moscow, Russia

Контактное лицо: Nugis V.Yu., E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: Study of chromosomal aberration yields with a three-color FISH method in the peripheral blood lymphocyte cultures of patients with breast cancer before and after local irradiation.

Material and methods: Venous blood was obtained from 24 patients aged from 33 to 79 years which suffering from cancer of the left or right breast after the implementation of a sectoral or radical resection of an affected organ with subsequent local adjuvant distant radiation therapy (DRT) to the scar area. Also it could be preceded by adjuvant polychimotherapy (PCT). A linear accelerator of the Trilogy system based on the Clinac iX platform was used for local irradiation. SOD was installed at 50 Gy per 25 fractions (daily 2 Gy). venous blood sampling produced to PCT and/or DRT and after 1 and/or 3 months after irradiation. A set of DNA probes to 1, 4 and 12 pairs of chromosomes was used for three-color FISH staining.

Results: Levels of translocations, dicentrics and acentrics (per 100 cells) in peripheral blood lymphocyte cultures of patients up to DRT did not differ significantly with and without PCT and were amounted to average 0.63 ± 0.10; 0.10 ± 0.04 and 0.17 ± 0.06, respectively. The frequency of these chromosome rearrangements significantly increased after radiation therapy by an average of up to 4.62 ± 0.46; 1.48 ± 0.19 and 0.95 ± 0.14. The differences between 1 and 3 months of taking material after irradiation were absent. One of the patients, unlike the rest, was cytogenetically examined 11 years after a similar local irradiation, and the frequencies of translocations and dicentrics in her lymphocyte culture were 4.56 and 0.19 (per 100 cells), respectively, while they were varied from 1.63 to 10.00 for translocations and from 0.27 (0 in one patient) to 4.06 for dicentrics for other patients.

Conclusion: When using a three-color FISH method there was a significant increase in the frequencies of translocations, dicentrics and acentrics in peripheral blood lymphocyte cultures of patients after DRT of breast cancer. At the same time there were more translocations than dicentrics and, apparently, they remain at the initial level for a long time. The frequency of translocations per 1 cell with translocations in the peripheral blood lymphocyte cultures in most cases exceeds 1 after local DRT of the breast cancer. The correlation between average physical doses to the whole body and cytogenetical estimates in individual patients was statistically insignificant.

Keywords: peripheral blood lymphocytes culture, three-color FISH method, translocations, breast cancer, local gamma-irradiation

For citation: Nugis VYu, Astrelina TA, Nikitina VA, Kozlova MG, Kobzeva IV, Lomonosova EE, Suchkova YuB, Usupzhanova DYu, Brunchukov VA, Rastorgueva AA, Malivanova TF, Brumberg VA, Karaseva TV, Lyubaeva ES, Bobrov DYu, Stepanyants NG, Sukhova MYu, Samoilov AS. Three-Color FISH Method: Translocations in Peripheral Blood Lymphocytes Cultures before and after Local Gamma Radiation for Breast Cancer. Medical Radiology and Radiation Safety. 2022;67(4):62-68. DOI: 10.33266/1024-6177-2022-67-4-62-68

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Informed Consent

All patients signed an informed consent to participate in the study.

Article received: 11.04.2022.  Accepted for publication: 11.05.2022

 

 

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