JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
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The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
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The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4
X-ray and Radionuclide Imaging in the Diagnosis
of ACTH-Producing Neuroendocrine Tumors
O.O. Golounina1, K.Yu. Slashchuk2, A.V. Khairieva2, N.V. Tarbaeva2,
M.V. Degtyarev2, Zh.E. Belaya2
1I.M. Sechenov First Moscow State Medical University, Moscow, Russia
2The National Medical Research Center for Endocrinology, Moscow, Russia
Contact person: Golounina Olga Olegovna, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Ectopic ACTH syndrome caused by excessive production of adrenocorticotropic hormone (ACTH) by a neuroendocrine tumor (NET) is an extremely rare disease, the main manifestation of which is pronounced hypercortisolism. In order to avoid the development of life-threatening complications and disability of the patient, timely topical diagnosis and rapid decision-making on further management tactics are necessary. The problem of the diagnosis of NET and differential diagnosis with other formations remains relevant and one of the little-studied. Despite the existing wide arsenal of methods of conventional diagnostics, functional and receptor imaging, the source of the disease remains unidentified in about 20% of patients. This article discusses the modern possibilities of NET visualization using conventional and radionuclide imaging methods, demonstrates the diagnostic capabilities of somatostatin-receptor scintigraphy and single-photon emission computed tomography combined with computed tomography (SPECT/CT) and combined positron emission and computed tomography (PET/CT) in the visualization of NET producing ACTH, and analyzes existing radiopharmaceuticals.
Keywords: multislice computed tomography, somatostatin-receptor scintigraphy, SPECT/CT, PET/CT, ectopic ACTH syndrome; neuroendocrine tumor (NET)
For citation: Golounina OO, Slashchuk KYu, Khairieva AV, Tarbaeva NV, Degtyarev MV, Belaya ZhE. X-ray and Radionuclide Imaging in the Diagnosis of ACTH-Producing Neuroendocrine Tumors. Medical Radiology and Radiation Safety. 2022;67(4):80-88. DOI: 10.33266/1024-6177-2022-67-4-80-88
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. Research supported by the Russian Science Foundation (RSF grant 19-15-00398-P)
Contribution. Article was prepared with equal participation of the authors
Article received: 20.04.2022. Accepted for publication: 24.06.2022
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4
Research of Dosimetric Characteristics of Human Hair Depending on the Content of Melanine
D.V. Ivanov1,3, D.R. Baitimirov1, S.F. Konev1, E.K. Vasilenko2,
E.E. Aladova2
1B.N. Yeltsin Urals Federal University, Yekaterinburg, Russia
2Southern Urals Biophysics Institute, Ozersk, Russia
3M.N. Mikheev Institute of Metal Physics, Ural Branch of the RAS, Yekaterinburg, Russia
Contact person: Aladova Е.Е., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Investigation of paramagnetic properties of radiation-induced centers that occur when hair samples are irradiated with ionizing radiation, depending on the color of the sample.
Material and methods: A Bruker Elexsys E580 electron paramagnetic resonance spectrometer was used. To improve the signal-to-noise ratio, the spectrum was recorded with three accumulations with a constant scan time equal to one minute. Measurements were made using a highly sensitive rectangular Bruker SuperHighQ resonator. For irradiation of samples, the linear electron accelerator UELR-10-10С2 of the innovation and implementation center for radiation sterilization of the Urals Federal University (Institute of Physics and technology) was used.
Results: Research of the EPR signal parameters of the melanin in hair samples of different colors (black, brown, red and gray with different degrees of pigmentation) showed that the intensity of the EPR signal varies depending on the hair color. The higher the radiation sensitivity of the hair, the lighter the color of the hair. The melanin signal, which is the background for the radiation-induced signal, increases with increasing intensity of hair color.
Key words: dosimetry, electron paramagnetic resonance, melanin, radiation sensitivity, human hairs
For citation: Ivanov DV, Baitimirov DR, Konev SF, Vasilenko EK, Aladova EE. Research of Dosimetric Characteristics of Human Hair Depending on the Content of Melanine. Medical Radiology and Radiation Safety. 2022;67(4):89-95. DOI: 10.33266/1024-6177-2022-67-4-89-95
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The work was carried out within the framework of state contract No. 11.310.19.2 on the topic “Improving the provision of emergency preparedness and response of the South Ural Regional Medical and Dosimetric Emergency Center in the event of radiation accidents” (code “Response-19”), funded by the Federal Medical and Biological Agency of Russia. EPR measurements were partly carried out within the framework of the state order of the Ministry of Education and Science of Russia (topic "Spin", No. AAAA-A18-118020290104-2).
Contribution. Article was prepared with equal participation of the authors
Article received: 15.03.2022.
Accepted for publication: 23.04.2022
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4
To the Question About Pharmacological Protection During Irradiation In Non-infecting Doses: Maybe, Necessary?
Communication 2.
Review of Pathogenetic Aspects and Methods for Assessing the Efficiency of Anti-Radiation Agents in Experiment
A.V. Ivanchenko1, V.A. Basharin2, I.S. Drachev1, A.B. Seleznev1, A.Yu. Bushmanov3
1Scientific Research Testing Institute of Military Medicine, St. Petersburg, Russia.
2S.M. Kirov Military Medical Academy, St. Petersburg, Russia.
3A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: Alexander Viktorovich Ivanchenko, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Review and systematization of modern ideas about the mechanisms of the development of the effects of ionizing radiation in medium doses on a living organism in order to assess the need and possibility of using pharmaceutical agents suitable for modification purposes, about research methods in experiment; stimulation of discussion on the issue under consideration.
Results: the current understanding of the genesis of radiation effects from irradiation at medium doses in the range of 0.2-1 Gy as a subject of modification with antiradiation agents is considered.
Conclusions: The systematic nature of modern knowledge about the genesis of radiation effects from low-power irradiation in medium doses of the range 0.2-1 Gy, heterogeneity and mixing of mechanisms can be considered as a basis for the use of antiradiation agents with different properties and aimed at target (direct) and non-target (indirect) ) the effect of radiation. One of the problems of using and predicting the radioprotective efficiency of the PLC is the poor development of methods for establishing correlations between the indicators of increased radioresistance (without irradiation) with the actual antiradiation effect.
Keywords: irradiation, average doses, pathogenesis of consequences, methods of assessment in experiment, antiradiation agents, disputability of use
For citation: Ivanchenko AV, Basharin VA, Drachev IS, Seleznev AB, Bushmanov AYu. To the Question About Pharmacological Protection During Irradiation In Non-infecting Doses: Maybe, Necessary? Communication 2. Review of Pathogenetic Aspects and Methods for Assessing the Efficiency of Anti-Radiation Agents in Experiment. Medical Radiology and Radiation Safety. 2022;67(4):101-112. DOI: 10.33266/1024-6177-2022-67-4-101-112
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors
Article received: 28.03.2022. Accepted for publication: 23.05.2022
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4
Anti-Glomerular Basement Membrane Antibody Disease
with Mild Kidney Failure and Without Progression of Lung Pathology: Case Report
Sheikh Zh.V. 1,2, Nikolaev E.V.1, Gazaryan Ya.R.1, Safonova T.D.1, Zakharova E.V. 1,2
1Russian Medical Academy of Continued Professional Education, Moscow, Russia.
2S.P. Botkin’s City Clinical Hospital, Moscow, Russia.
Contact person: Zhanna V. Sheikh; E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Anti-GBM antibody disease (Goodpasture syndromee) is a rare immunecomlpex vasculitis, affecting small vessels, and characterized by rapidly progressive glomerulonephritis and alveolitis. Causative mechanism is defined by the hyperproduction of autoantibodies against the α3-chain of type IV collagen (Goodpasture antigen) with immune complex formation on the glomerular and alveolar basement membrane. Typically patients with fnti-GBM antibody disease present with rapidly progressive (crescentic) glomerulonephritis, more than in half of cases associated with alveolar hemorrhage. Cases of Anti-GBM antibody disease with atypical clinical presentation have been reported.
We report a case of atypical clinical presentation anti-GBM antibody disease with mild renal damage and slow progression of pulmonary involvement. Main CT signs were multiple centrilobular ground glass nodules.
This case report demonstrates that CT with disseminated pulmonary process associated with even mild kidney involvement in patients with high anti-GBM antibodies titers gives a clue to the diagnosis of anti-GBM antibody disease.
Keywords: Goodpasture syndrome, anti-GBM antibody disease, glomerulonephritis, computed tomography, case report.
For citation: Sheikh ZhV, Nikolaev EV, Gazaryan YaR, Safonova TD, Zakharova EV. Anti-glomerular basement membrane antibody disease with mild kidney failure and without progression of lung pathology: case report. Medical Radiology and Radiation Safety. 2022;67(4):96-100. DOI: 10.33266/1024-6177-2022-67-4-96-100
References
1. Jennette J.C., Nickeleit V. Anti-Glomerular Basement Membrane Glomerulonephritis and Goodpasture Syndrome. Heptinstall’s Pathology of the Kidney. Eds. Jennette J.C., Silva F.G., Olson J.L., et al. Philadelphia, Wolters Kluwer, 2015. P. 657–684.
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors
Article received: 28.03.2022. Accepted for publication: 23.05.2022
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 4
Igor Borisovich Keirim-Markus
(on the Occasion of His 100th Birthday)
I.L. Efimova
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia.
Contact person: Efimova Irina Leonidovna, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
The article contains material on the scientific activity and life path of a well-known scientist in the field of radiation safety, the first head of the laboratory of emergency and individual dosimetry, one of the developers of the first neutron dosimeter in the USSR. This publication is a historical review of materials from the collection of the Museum of the FMBTS. A.I.Burnazyan, the archive of the scientist’s family, printed publications, is of scientific interest because it holistically presents the life and scientific path of the famous scientist who gave 58 years of service to science within the walls of the Institute of Biophysics (now part of the A.I.Burnazyan FMBC) .
The scientist made a great contribution to the formation of a new area of science at the intersection of dosimetry, radiobiology and radiation medicine, named equidosimetry at his suggestion. The museum keeps the book of I.B.Keirim-Markus "Equidosimetry", where for the first time in the world scientific literature summarized materials on the main sections of equidosimetry, the history of its occurrence, tasks, criteria for assessing the effect of radiation, in particular in large doses, the values of equidosimetry, methods and instruments for their measurement.
Keywords: Kerim-Markus I.B., biophysics, dosimetry, radiation safety, equidosimetry, radiation sickness, Chernobyl accident
For citation: Efimova IL. Igor Borisovich Keirim-Markus (on the occasion of his 100th birthday). Medical Radiology and Radiation Safety. 2022;67(4):113-116. DOI: 10.33266/1024-6177-2022-67-4-113-116
References
1. Memoirs of I.B. Keirim-Markus. About the militia and beyond. From the archive of the family of I.B. Keirim-Markus. Internet resources. website http://jolaf.jnm.ru/keirim-markus/
2. Order No. 55 of the director of the SSC-RF-Institute of Biophysics L.A. Ilyin on the declaration of gratitude to I.B. Keirim-Markus. 09/05/1997. Fund of the Museum of the FMBC named after. A.I. Burnazyan
3. Memoirs of V.N. Klochkov. Fund of the Museum of the FMBC named after. A.I. Burnazyan
4. L.A. Ilyin. Realities and myths of Chernobyl. M., 1996, p.274
5. In memory of I.B. Keirim-Markus// Equipment and news of radiation measurements, 2006, No. 3(46), p.71
6. Memories of the father of T.I. Yuganova. From the archive of the family of I.B. Keirim-Markus. 2022
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. The article was prepared by one author.
Article received: 19.02.2022. Accepted for publication: 23.03.2022