JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2023. Vol. 68. № 1
DOI: 10.33266/1024-6177-2023-68-1-86-91
V.I. Chernov1,2, E.A. Dudnikova1, R.V. Zelchan1,2, O.D. Bragina1,2,
A.A. Medvedeva1, A.N. Rybina1, A.V. Muravleva1, T.L. Kravchuk1, V.E. Goldberg1
Single-Photon Emission Computed Tomography with 99mTс-1-Thio-D-glucose in Evaluation of the Effectiveness and Prediction of the Results of Treatment of Lymphoproliferative Diseases
1Cancer Research Institute, Tomsk National Research Medical Center, Tomsk, Russia
2 Research Centrum for Oncotheranostics, Tomsk Polytechnic University, Tomsk, Russia
Contact person: V.I. Chernov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Study of 99mTc-1-thio-D-glucose (99mTc-TG) SPECT using fore possibility to assess the effectiveness of therapy and predict the results of lymphomas treatment.
Material and methods: We analyzed 99mTc-TG SPECT data of 30 people with malignant lymphomas: before treatment (SPECT1), after two courses (SPECT2) and after completion of chemotherapy (SPECT3).
Results: By the results of SPECT2 analyzing, a complete metabolic response after two courses of chemotherapy (SPECT2–) was observed in 15 patients (50 %). In 15 patients, after 2 cycles of chemotherapy, a partial metabolic response (12 people) or no metabolic response
(3 people) was established. These patients constituted the SPECT2+ group.
After completion of chemotherapy, a complete metabolic response (SPECT3–) was diagnosed in 21 (70 %) patients. This effect was obtained in 15 (100 %) patients with SPECT2– and in 6 patients (40 %) with SPECT2+. Of the 15 patients in the SPECT2+ group, 9 (60 %) patients after completion of chemotherapy were diagnosed with a partial metabolic response (6 people) or metabolic progression (3 people).
By two-year follow-up of patients, show that remission was observed in 23 (77 %) patients (complete remission in 15 people, uncertain complete remission in 8 patients). The relapse group consisted of 7 (23 %) cases, while 4 patients had a relapse of the disease, and 3 had progression. In SPECT2+ group, relapse of the disease was observed in 6 (40 %) cases, and remission in 9 (60 %) patients. While in SPECT2– group 1 (7 %) person relapse was diagnosed and 14 (93 %) were in remission (p<0.05).
Conclusion: 99mTc-TG SPECT makes it possible to evaluate the results of lymphomas treatment with high efficiency. The presence of a complete metabolic response of the tumor after two courses of therapy indicates a high level of disease-free survival.
Keywords: 99mTc-1-thio-D-glucose, single photon emission computed tomography, Hodgkin’s lymphoma, Non-Hodgkin’s lymphomas, lymphoma therapy, prognosis
For citation: Chernov VI, Dudnikova EA, Zelchan RV, Bragina OD, Medvedeva AA, Rybina AN, Muravleva AV, Kravchuk TL, Goldberg VE. Single-Photon Emission Computed Tomography with 99mTс-1-Thio-D-glucose in Evaluation of the Effectiveness and Prediction of the Results of Treatment of Lymphoproliferative Diseases. Medical Radiology and Radiation Safety. 2023;68(1):86–91. (In Russian). DOI: 10.33266/1024-6177-2023-68-1-86-91
References
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12. Chernov V.I., Dudnikova Ye.A., Zelchan R.V., et al. The First Experience of Using 99mTc-1-Thio-d-Glucose for Single-Photon Emission Computed Tomography Imaging of Lymphomas. Sibirskiy Onkologicheskiy Zhurnal = Siberian Journal of Oncology. 2018;17;4:81–87. DOI: 10.21294/1814-4861-2018-17-4-81-87 (In Russ.).
13. Dudnikova Ye.A., Chernov V.I., Muravleva A.V., et al. Metabolic Single-Photon Emission Computed Tomography with the New Radiopharmaceutical 99mTc-1-Thio-D-Glucose in the Diagnosis and Monitoring of the Primary Breast Lymphoma (Case Report). Sibirskiy Onkologicheskiy Zhurnal = Siberian Journal of Oncology. 2020;19;5:145–153. doi: 10.21294/1814-4861-2020-19-5-145-153 (In Russ.).
14. Muravleva A.V., Chernov V.I., Dudnikova Ye.A., et al. Metabolic single-Photon Emission Computed Tomography with «99mTc-1-Thio-D-Glucose» - New Possibilities for Hodgkin’s Lymphoma Staging. Rossiyskiy Elektronnyy Zhurnal Luchevoy Diagnostiki = Russian Electronic Journal of Radiology. 2021;11;3:171–177. DOI: 10.21569/2222-7415-2021-11-3-171-177 (In Russ.).
15. Chernov V., Dudnikova E., Zelchan R., et al. Phase I Clinical Trial Using [99mTc]Tc-1-Thio-D-Glucose for Diagnosis of Lymphoma Patients. Pharmaceutics. 2022;14:1274. https://doi.org/10.3390/pharmaceutics14061274.
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.09.2022. Accepted for publication: 25.11.2022.
Medical Radiology and Radiation Safety. 2023. Vol. 68. № 1
DOI: 10.33266/1024-6177-2023-68-1-92-100
S.M. Rodneva1, D.V. Guryev1,2
Tritium Dosimetry at the Cellular Level
1A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
2N.N. Semenov Federal Research Center for Chemical Physics, Moscow, Russia
Contact person: Sofya Mikhailovna Rodneva: e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
CONTENTS
Introduction
1. Tritium radioisotope and its energy spectrum
2. Methods for calculating doses from radiation of radionuclides
2.1 General equation for absorbed dose rate
2.2 Absorbed dose rate versus average energy
2.3 Formulas for calculating dose and S-values from radiation of radionuclides
2.4 Method of dose point nuclei
2.5 MIRD effective stopping power method
2.6 Geometric factor
3. Analysis of S-value calculations by various methods
3.1 Values of the CSDA range at low initial electron energies
3.2 Comparison of S-value calculations for low energy electrons
3.3 Comparison of tritium S-value calculations
4. Evaluation of S-value calculations in the absence of spherical symmetry
Conclusion
Keywords: radiation dosimetry, radionuclides, tritium, electrons, S-value, cell, mathematical model
For citation: Rodneva SM, Guryev DV. Tritium Dosimetry at the Cellular Level. Medical Radiology and Radiation Safety. 2023;68(1):92–100. (In Russian). DOI: 10.33266/1024-6177-2023-68-1-92-100
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.09.2022. Accepted for publication: 25.11.2022.
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 6
DOI: 10.33266/1024-6177-2022-67-6-12-18
A.A. Kosenkov, F.S. Torubarov, M.Yu. Kalinina, S.A. Afonin
Some Organizational and Methodological Aspects of Psycho-Physiological Support
of Functional Reliability of Russian Nuclear Workers
A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: A.A. Kosenkov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To improve organizational and methodological approaches to psycho-physiological support of functional reliability of Russian nuclear workers.
Results: The authors’ position on a number of topical organizational and methodological issues of psycho-physiological support of functional reliability of nuclear workers is presented.
Measures aimed at optimizing the interaction of medical organizations of the FMBA of Russia and organizations of the Rosatom State Corporation in the preparation and conduct of psychophysiological examinations are proposed. The optimal solution to this problem, according to the authors, is the development of a joint regulatory document defining the rights and obligations of both parties by the FMBA of Russia and the State Corporation. The expediency of avoiding duplication in carrying out a number of diagnostic techniques after developing a mechanism for transferring test results from medical organizations of the FMBA of Russia to organizations of the Rosatom State Corporation is shown.
According to the authors, the following issues are to be improved: a) the existing diagnostic arsenal, taking into account new technological capabilities, and having in mind the fact that some important tests are easily available on the Internet; b) the content of methodological recommendations, which should describe in detail sensorimotor and other tests, allowing for a variety of their interpretations, to ensure the invariance of their computer implementations. Such measures will increase the diagnostic value of the tests used, as well as the comparability of the results obtained using various software and hardware complexes.
Authors also propose to reconsider the role of the Scientific and Technical Council of the State Corporation in improving the functional reliability of the personnel of the industry by integrating psycho-physiological and other areas related to human resources into the general research topics. Proposed actions:
a) to create a thematic scientific and technical council on human resource management and reduction of anthropogenic risks including specialists in psycho-physiological, psychological, medical, sanitary-hygienic, ergonomic and other aspects of ensuring the functional reliability of personnel, and to elect a scientific adviser of the council;
b) to include the development plan for the direction of ensuring the functional reliability of personnel in the new edition of the “Program of Innovative Development and Technological Upgrading of the Rosatom State Corporation for the Period up to 2030”;
c) to add the direction on improving the reliability of the human factor in the Unified Industry Thematic Plan of Research and Development Work of the Rosatom State Corporation;
d) to include the most important reports related to human resource management and reduction of anthropogenic risks in the plenary sessions of the conferences “Radiation Protection and Radiation Safety in Nuclear Technologies”.
Conclusion: The above proposals are aimed at improving the organizational and methodological aspects of the psycho-physiological direction in ensuring the functional reliability of nuclear workers. According to the authors, this direction should be part of the human resource management system and the reduction of anthropogenic risks in the nuclear industry. The research part of this system should be integrated into the activities of the Scientific and Technical Council of the Rosatom State Corporation and meet the requirements of a systematic approach.
Keywords: nuclear industry, safety, functional reliability, nuclear workers, professionally important qualities, anthropogenic risks, regulatory documents, psychophysiological laboratory
For citation: Kosenkov AA, Torubarov FS, Kalinina MYu, Afonin SA. Some Organizational and Methodological Aspects of Psycho-Physiological Support of Functional Reliability of Russian Nuclear Workers. Medical Radiology and Radiation Safety. 2022;67(6):12–18. (In Russian). DOI:10.33266/1024-6177-2022-67-6-12-18
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.07.2022. Accepted for publication: 25.09.2022.
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 6
DOI: 10.33266/1024-6177-2022-67-6-5-11
I.V. Kobzeva1, T.A. Astrelina1, V.A. Brunchukov1, V.A. Brumberg1, A.A. Rastorgueva1,
Yu.B. Suchkova1, D.Yu. Usupzhanova1, T.F. Malivanova1, V.A. Nikitina1, S.V. Lishchuk1,
E.A. Dubova1, K.A. Pavlov1, Ya.V. Tonkal1, O.F. Serova1,2, A.S. Samoilov1
Transplantation of Human Decellularized Amniotic Membrane in Local Radiation Injuries
1A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
2Moscow Regional Perinatal Center, Balashikha, Russia
Contact person: T.A. Astrelina, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Evaluation of the effectiveness of the use of human decellularized amniotic membrane, both as an independent covering material and as a cell-free matrix for syngeneic regenerative cells of adipose tissue (stromal-vascular fraction – SVF, adipose tissue ‒ AT) in local radiation injuries (LRI) IIIb-IV severity in laboratory animals.
Material and methods: 42 laboratory animals were studied. LRI modeling was carried out on an X-ray at a dose of 110 Gy. Animals were randomized randomly and divided into 6 groups depending on the type of treatment:
1st group (K) ‒ control group animals after irradiation did not receive specific treatment; the 2nd group (Gl) ‒ after irradiation, medical glue BF-6 was applied to the ulcer surface on the 21st day; 3rd group (Am) ‒ animals after irradiation on the ulcer surface was applied decellularized amniotic membrane, fixed with interrupted sutures on the 21st day; 4th group (Am-Gl) ‒ animals after irradiation on the ulcer surface was applied decellularized amniotic membrane, fixed with medical adhesive BF-6 for 21 days; 5th group (SVF-Gl) ‒ after irradiation, the SVF AT at a dose of 0.4×106 cells was applied to the ulcer surface after irradiation, followed by fixation with BF-6 medical glue for
21 days; the 6th group (Am-SVF) ‒ after irradiation, SVF AT was applied to the ulcer surface at a dose of 0.4×106 cells under the decellularized amniotic membrane, fixed with interrupted sutures on the 21st day.
Results: On the 112th day, complete healing of the ulcer was observed in 100 % of animals in the Am-Gl group, in 70 % in the Am and Gl groups. There was no complete healing of the ulcer in the SVF-CGl and Am-SVF groups. The greatest reduction in the area of the total altered skin from 21 to 112 days of the experiment was noted in the groups Gl-SVF (34.7 %), K (31.6 %), Am-SVF (30.7 %). In the Am-Gl and Am groups, a reduction in the area of the total altered skin was recorded by 24.6 % and 14.7 %, respectively. In the GL group, the reduction in the area of the total altered skin was the smallest, by only 13.5 %.
Conclusion: The use of a decellularized human amniotic membrane fixed with medical adhesive BF-6 can be considered as a promising method for the conservative treatment of LRI of the skin.
Keywords: local radiation injury, transplantation, decellularized human amniotic membrane, efficacy, rat
For citation: Kobzeva IV, Astrelina TA, Brunchukov VA, Brumberg VA, Rastorgueva AA, Suchkova YuB, Usupzhanova DYu, Malivanova TF, Nikitina VA, Lishchuk SV, Dubova EA, Pavlov KA, Tonkal YaV, Serova OF, Samoilov AS. Transplantation of Human Decellularized Amniotic Membrane in Local Radiation Injuries. Medical Radiology and Radiation Safety. 2022;67(6):5–11. (In Russian). DOI:10.33266/1024-6177-2022-67-6-5-11
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PDF (RUS) Full-text article (in Russian)
Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Финансирование. Исследование не имело спонсорской поддержки.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Поступила: 20.07.2022. Принята к публикации: 25.09.2022.
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 6
DOI:10.33266/1024-6177-2022-67-6-19-23
A.Yu. Bushmanov, O.A. Kasymova, A.S. Kretov, M.A. Soloreva, E.A. Denisova
Results of Psychophysiological Examinations of Personnel of Nuclear Facilities
A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: A.S. Kretov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
The relationship between the employee’s level of health and his professional reliability is currently obvious and does not require additional evidence. The implementation of measures aimed at reducing the risks of emergency situations caused by the human factor at nuclear energy facilities is an important element of the radiation protection system.
In order to achieve the above-mentioned goals of the organization, in accordance with Federal Law № 170-FZ of 21.11.1995, the performance of certain types of work in the field of atomic energy use requires special permits from Rostechnadzor. A prerequisite for obtaining such a permit for a specialist is the absence of psychophysiological contraindications based on the results of a psychophysiological examination.
This study analyzes the results of psychophysiological examinations of employees of nuclear energy facilities conducted by specialists of the State Research Center – A.I. Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency in 2020 and 2021.
Keywords: nuclear industry, workers, psychophysiological examinations, psychophysiological contraindications, radiation safety
For citation: Bushmanov AYu, Kasymova OA, Kretov AS, Soloreva MA, Denisova EA. Results of Psychophysiological Examinations of Personnel of Nuclear Facilities. Medical Radiology and Radiation Safety. 2022;67(6):19–23. (In Russian). DOI:10.33266/1024-6177-2022-67-6-19-23
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.07.2022. Accepted for publication: 25.09.2022.