JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 10–17
Methodological Approaches to Measurement of Carbon-14 for Control of its Radiation
Impact on the Personnel and the Public
V.N. Klochkov, L.I. Kuznetsova, N.A. Eremina, D.I. Kabanov, A.A. Maximov,
S.V. Berezin, A.A. Androsova, E.V. Klochkova, P.P. Surin, V.K. Velichko
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: Klochkov Vladimir Nikolaevich: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Analysis of the current regulatory and methodological framework on control of doses from intake of 14С for the personnel and the public living in the control area of the nuclear power plant (NPP). Identifying the most informative methods of controlling radiation impact of 14С on a human being.
Material and methods: Research literature on radiation impact of naturally occurring 14С; 14С entering the environment as a result of nuclear weapon tests; and 14С entering workplaces and the control area of NPP has been reviewed. Dose coefficients and other radiation characteristics of 14С provided in IAEA, ICRP and UNSCEAR publications have been summarized.
Results: According to UNSCEAR, annual radiation burden caused by global 14С is the highest one (about 80 %) among radiation burdens associated with four critical naturally occurring cosmogenic radionuclides: 3Н (0.01 µSv/year), 7Be (3.0 µSv/year), 14С (12 µSv/year) and 24Na (0.2µSv/year). The main way of 14С intake is the alimentary one when this isotope enters the human body with food. Dose from this kind of intake of global 14С can reach 40 µSv. The annual dose caused by aerogenic (inhalation) way of intake of global 14С does not exceed 1 µSv.
The most informative methods of dose assessment for the personnel of NPP and the public living in the control area involve measurement of content of 14С in top soil, vegetation and food products.
Conclusions: Significant amount of 14С enters the environment within the control area during operation of NPP, which causes the public radiation dose exceeding the dose from global 14С. The most informative objects characterizing content of technogenic 14С in the control area of NPP are top soil (humus) and vegetation. The liquid scintillation spectrometry involves sample preparation by burning of samples in oxygen with capturing of generated carbon dioxide and its transfer into organic solvent. This is the most technologically viable method for mass control of 14С content in samples of top soil and vegetation.
Key words: radiation safety, carbon-14, control of specific activity, internal dose, soil, vegetation
For citation: Klochkov VN, Kuznetsova LI, Eremina NA, Kabanov DI, Maximov AA, Berezin SV, Androsova AA, Klochkova EV, Surin PP, Velichko VK. Methodological Approaches to Measurement of Carbon-14 for Control of its Radiation Impact on the Personnel and the Public. Medical Radiology and Radiation Safety. 2021;66(6):10-17.
DOI: 10.12737/1024-6177-2021-66-6-10-17
References
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 16.09.2021.
Accepted for publication: 22.10.2021.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 18–25
Radiation Safety in Nuclear Medicine: Report II. Normative Documents
B.Ya. Narkevich1,2
1Association of Medical Physicists of Russia, Moscow, Russia
2N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia
Contact person: Narkevich Boris Yaroslavovich: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
The specifics of improving current regulatory acts on nuclear medicine under the conditions of the "regulatory guillotine" are considered. The current state of regulatory documentation on ensuring the radiation safety of patients, personnel, individuals from the population and the environment, as well as on assessing working conditions and pension provision for personnel of domestic nuclear medicine units, is analyzed. The presence of a large number of provisions that are scientifically unsubstantiated and inconsistent with international recommendations and many years of nuclear medicine practice is shown. A number of proposals have been developed to introduce appropriate amendments to regulatory documents intended for practical use after the end of the “regulatory guillotine”.
Key words: radiation safety, medical radiology, regulatory documentation, the need for improvement, “regulatory guillotine”
For citation: Narkevich BYa. Radiation Safety in Nuclear Medicine: Report II. Normative Documents. Medical Radiology and Radiation Safety. 2021;66(6):18-25.
DOI: 10.12737/1024-6177-2021-66-6-18-25
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. The article was prepared by one author.
Article received: 17.07.2021.
Accepted for publication: 05.09.2021
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 34–38
Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice
Bychkova T.M.1,2, Andrianova I.E.1, Nikitenko O.V.1,2, Stavrakova N.M.1, Parfenova I.M.1, Karaulova T.A.1, Gordeev A.V.1, Ivanov A.A.1,2,3
1A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
2RFSSC Institute of Biomedical Problems, Moscow, Russia
3Joint Institute for Nuclear Research, Dubna, Russia
Contact person: Taisia Mikhailovna Bychkova: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Assessing the role of various factors in the formation of radioresistance is an important branch of radiobiology. The quality of drinking water, as it turned out, can significantly affect radioresistance. Against the background of studying the antiradiation properties of various types of water, differing in mineral and isotopic composition, the problem of the influence of tap water on the course of radiation injury remained underestimated. This circumstance determined the purpose of the work: to evaluate the modifying effect of tap water on the course of acute radiation sickness after X-ray irradiation of mice at an average lethal dose.
Material and methods: Female ICR (CD-1) mice were irradiated with an average lethal dose once – 6.5 Gy of X-ray irradiation. After irradiation, half of the mice received tap water as drinking water, and the other half received artificially mineralized drinking water.
Results: Keeping animals on tap water significantly reduced the survival rate of mice both with a single dose (log-rank test p=0.02, χ2=5.38) compared with animals receiving artificially mineralized distilled water. In addition, in the group of mice that received tap water, an increase in the rate of death of mice and a lower preservation of the group mass of animals during the development of acute radiation injury was noted.
Conclusion: Tap water, used as drinking water, increases the damaging effect of radiation when X-rays are irradiated in mice.
Key words: tap water, artificially mineralized distilled water, X-ray irradiation, survival rate, mortality rate, mice, model
For citation: Bychkova TM, Andrianova IE, Nikitenko OV, Stavrakova NM, Parfenova IM, Karaulova TA, Gordeev AV, Ivanov AA. Influence of Drinking Water Quality on the Current of Acute Radiation Disease in Mice. Medical Radiology and Radiation Safety. 2021;66(6):34–38.
DOI: 10.12737/1024-6177-2021-66-6-34-38
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 10.08.2021
Accepted for publication: 21.09.2021
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 26–33
Analysis of the Appearance of Micronuclei in the Erythrocytes and Activity of Bone Marrow Cells Proliferation after the Prolonged Low Dose Fast Neutrons Irradiation of Mice
E.Yu. Moskaleva, A.N. Romantsova, Yu.P. Semochkina, A.V. Rodina, I.V. Cheshigin, A.S. Degtyarev, A.S. Zhirnik
National Research Center «Kurchatov Institute», Moscow, Russia
Contact person: Elizaveta Yurievna Moskaleva: This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To analyze the level of cytogenetic damage and the activity of bone marrow cells proliferation in C57BL/6 mice after prolonged fast neutrons low dose irradiation at 10–500 mGy.
Material and methods: Male C57BL/6 mice at the age of 7–8 and 16 weeks were used in the experiments. Irradiation was carried out on an OR-M installation in the field of fast neutrons and gamma quanta using five Pu(α,n)Be radionuclide sources with a high fast neutron yield at a dose rate of 2.13 mGy/h. The frequency of polychromatophilic (PCE) and normochromic (NCE) erythrocytes with micronuclei (MN) and the ratio of PCE and NCE were analyzed using light microscopy after cytochemical staining of the bone marrow cells of control and irradiated mice. The proliferation activity of bone marrow cells was determined by the number of Ki-67+-cells. The parameters of the cell cycle and the level of apoptosis were studied after DNA staining with DAPI using flow cytometry. Statistical processing of the results was carried out according to the Student’s method using the computer program Origin.
Results: It was found that prolonged irradiation of mice with fast neutrons at a low dose rate (2.13 mGy/h) at doses from 10 to 500 mGy after 24 h led to statistically significant increase in the frequency of PCE with MN at all studied doses. No dose dependence of this parameter was observed in the studied range. The increase in the frequency of PCE with MN at a dose of 500 mGy was prolonged and persisted for at least 72 h. A significant increase in the frequency of NCE with MN 24 h after irradiation was found only at a dose of 500 mGy, which persisted up to 48 h. At this dose, there was also a decrease in the number of nucleated cells in the bone marrow 24 – 72 h after exposure, a decrease in the number of Ki-67+-cells 24 h after irradiation of mice, a block of the cell cycle in the G2/M phase, and a decrease of cells in the G0/G1 phase, but after 48 h, there were no disturbances in the cell cycle.
Conclusion: It has been shown that after a single total prolonged irradiation of mice at low doses (10–500 mGy), when analyzing the frequency of PCE with MN, cytogenetic damage is recorded in the bone marrow, which indicates the genetic danger of exposure to even such low levels of fast neutron irradiation. A decrease in Ki67+ cells and cell cycle arrest at the G2/M phase were found only after irradiation of mice at a dose of 500 mGy and only 24 h after exposure, while the number of nucleated cells in the bone marrow at this dose was reduced, at least to 72 h.
Key words: micronuclei, bone marrow, cell cycle, cell proliferation, Ki-67, fast neutrons, prolonged irradiation, low dose, mice
For citation: Moskaleva EYu, Romantsova AN, Semochkina YuP, Rodina AV, Cheshigin IV, Degtyarev AS, Zhirnik AS. Analysis of the Appearance of Micronuclei in the Erythrocytes and Activity of Bone Marrow Cells Proliferation after the Prolonged Low Dose Fast Neutrons Irradiation of Mice. Medical Radiology and Radiation Safety. 2021;66(6):26–33.
DOI: 10.12737/1024-6177-2021-66-6-26-33
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 10.08.2021
Accepted for publication: 21.09.2021.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 39–44
Comparative Analysis of Paired Correlations Structure Between Psychological Scales
in Relation to Groups of Different Sizes
A.A. Kosenkov
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: Alexander Kosenkov: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To propose a procedure for comparative analysis of correlation relationships structure between psychological scales in samples of different sizes.
Material and methods: A procedure of comparative analysis of correlation relationships structure between psychological indicators in groups of different sizes based on the «zet» method of R. Fisher is proposed. To illustrate the method, data from psychodiagnostic surveys of the nuclear power plant (NPP) personnel who worked in normal conditions and the personnel of the Chernobyl NPP at four different stages of aftermath activities in 1986–1987 were used. All the subjects performed the Minnesota Multiphasic Personality Inventory (MMPI); the results of each of the groups were subjected to a correlation analysis using the Pearson method. The analysis took into account average (0.5 ≤ r < 0.7) and strong (r ≥ 0.7) correlations.
Results: Using the example of a number of psychodiagnostic examinations of the Chernobyl NPP personnel at various stages of aftermath activities, it is shown that the structure of correlation relationships between the MMPI scales can reflect the peculiarities of mental adaptation of professional teams working in regular and extreme conditions.
It was shown that in the aftermath process by March–April 1987, the number of medium and strong pairwise Pearson correlations between the clinical MMPI scales increased. This fact apparently indicates that during this period, the NPP personnel were characterized by the simultaneous activation of various mechanisms of intrapsychic adaptation. The core of the correlation pleiad consisted of scales 1, 2, 7, and 8. Such a multidirectional reaction to the aftermath stressors was accompanied by a statistically significant increase in almost all clinical scales (except scale 6) of the average MMPI profile in comparison with the control group. The absence of stable correlations of clinical scales with the F scale indicates that the marked increase in the MMPI profile was not associated with a tendency to aggravation.
By the period of November–December 1987, the hypochondria scale occupied a leading place in the correlation pleiad of the MMPI indicators of the Chernobyl NPP personnel, the number of its significant connections with other clinical scales (2, 3, 7 and 8) reached four. Apparently, the mechanism of anxiety somatization at that time could be considered as a syndrome-forming factor and taken into account when planning rehabilitation and health measures.
Conclusion: The use of the proposed method of the strength standardization of pairwise correlation relationships between the MMPI scales allowed us to legitimately compare these indicators in groups that differ significantly in number. The chosen representation form of correlations facilitates the analysis of their structure.
Key words: Pearson’s correlation coefficient, correlation pleiad, psychic adaptation, MMPI, Chernobyl NPP
For citation: Kosenkov A.A. Comparative Analysis of Paired Correlations Structure Between Psychological Scales in Relation to Groups of Different Sizes. Medical Radiology and Radiation Safety. 2021;66(6): 39–44.
DOI: 10.12737/1024-6177-2021-66-4-39-44
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. The article was prepared by one author.
Article received: 18.09.2021
Accepted for publication: 22.10.2021