JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 18–22
The Ratio of the Extraversion and Fluid Intelligence Levels as a Predictor of the Operators’ Successful Professional Activity
A.A. Kosenkov
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: Aleksandr Kosenkov: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Results: To study the relationship between the ratio of the extraversion and fluid intelligence levels with the success of the professional activity of the nuclear power plants (NPP) operators.
Material and methods: This paper analyzes the results of psychodiagnostic examinations of operators of main control rooms of NPPs that functioned under normal conditions. All individuals were administered the J. Raven's “Progressive matrices”, the Russian language adaptation of the Minnesota Multiphasic Personality Inventory (MMPI) and the Sixteen Personality Factor Questionnaire (16PF, form A). Cross-peer review using the ranking method identified 5 groups of operators with different levels of professional success (from markedly reduced to high).
Results: Using factor analysis, the dimension of the data matrix obtained during the surveys was reduced. Correlation analysis showed that out of 9 identified factors, only 2 had a statistically significant correlation with the success of professional activity, namely, the factors of extraversion (negative relationship) and intelligence (positive relationship). Based on these two factors, an automatic classification of operators was carried out using cluster analysis, as a result of which 5 classes of operators were identified. It was shown that classes A and B with a predominance of the extraversion factor included mainly (79 %) operators with a level of professional success below average. On the contrary, classes C, D and E with a predominance of the intelligence factor consisted mainly (81 %) of operators with average and above average levels of professional success. It is noteworthy that the average value of intelligence factor in one of the classes consisting of operators, advantageously with lower professional success rate (class B) was the same or even 10 T-scores higher in comparison with the classes represented mainly by operators whose success rate was assessed from medium to high.
Conclusion: Factors of extraversion and intelligence are associated with the quality of performance of professional duties by the NPP control room operators under normal operating conditions. At the same time, the success of their professional activity depends not so much on the quantitative values for these factors, but on their ratio, namely: the predominance of the intelligence factor is prognostically favorable.
Key words: nuclear power plant, operators, main control room, extraversion, intelligence, success of professional activity,
psychological professional selection
For citation: Kosenkov AA. The Ratio of the Extraversion and Fluid Intelligence Levels as a Predictor of the Operators’ Successful Professional Activity. Medical Radiology and Radiation Safety 2021;66(5):18-22.
DOI: 10.12737/1024-6177-2021-66-5-18-22
References
1. Atroshenko YK. Automated Control Systems for Nuclear Power Plants: Textbook. YK Atroshenko, EV Ivanova; Tomsk Polytechnic University. Tomsk: Publishing House of the Tomsk Polytechnic University, 2014. (In Russian).
2. Duel MA, Kanyuk MI. Automation of Technological Processes and its Impact on the Efficiency of Energy Production at TOPs and NPPs. Eastern European Journal of Advanced Technologies. 2011;5;8;53:15-22. (In Russian).
3. Kosenkov AA. Psychological Factors of Professional Success of Nuclear Power Plant Main Control Room Operators. Saratov journal of Medical Scientific Research. 2014;10;4:758-61. (In Russian).
4. Cattell RB. Intelligence: Its Structure, Growth and Action. New York: Elsevier Publ. 1987.
5. Plomin R, von Stumm S. The New Genetics of Intelligence. Nature Reviews Genetics. 2018;19;3:148-159. DOI:10.1038/nrg.2017.104.
6. Eysenck HJ. Personality, Genetics and Behavior: Selected Papers. New York: Praeger Publ. 1982.
7. Frager RD, Fadiman J. Personality: Theories, Experiments, Exercises. St. Petersburg: Prime-Evroznak Publ., 2004. Pp. 608. (In Russian).
8. Bodrov VA. Psychology of Professional Activity. Theoretical and Applied Problems. Moscow: The Institute of Psychology RAN Publ., 2006. Pp. 623. (In Russian).
9. Cattell RB, Horn JL. A check on the Theory of Fluid and Crystallized Intelligence with Description of New Subtest Designs. Journal of Educational Measurement. 1978;15;3:139–164. https://doi.org/10.1111/j.1745-3984. 1978.tb00065.x.
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12. Mishkevich AM. Extraversion in Various Personality Theories. Penza Psychological Bulletin. 2019;1;12:52-69. (In Russian).
13. Blickle G, Meurs JA, Wihler A, Ewen C, Merkl R, Missfeld T, Extraversion and Job Performance: How Context Relevance and Bandwidth Specificity Create A Non-Linear, Positive, and Asymptotic Relationship, Journal of Vocational Behavior. 2015;87:80-88, https://doi.org/ 10.1016/j.jvb.2014.12.009.
14. Grant AM, Schwartz B. Too Much of a Good Thing: The challenge and Opportunity of the Inverted U. Perspectives on Psychological Science. 2011;6:61-76.
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16. Kumar D, Kapila A. Problem Solving as a Function of Extraversion and Masculinity. Personality and Individual Differences. 1987;8;1:129-132. https://doi.org/10.1016/0191-8869(87)90020-1.
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared by one author
Article received: 23.12.2020.
Accepted for publication: 20.01.2021.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 23–32
Radiation-Hygienic Investigations of Experimental Production of Mixed Nitride Uranium-Plutonium Fuel at JSC SChC. Part 1: Methods and Results
L.A. Ilin 1, A.S. Samoylov 1, A.G.Tsovyanov 1, S.M. Shinkarev 1, N.K. Shandala 1, P.P. Gantsovsky 1, A.E. Karev 1, B.A. Kukhta 1, A.V. Simakov 1, V.N. Klochkov 1, I.P. Korenkov1, A.M. Lyaginskaya 1, O.V. Parinov 1, V.M. Solomatin 2, K.M. Izmestyev 3
1SRC FMBC of FMBA, Moscow, Russia
2JSC Proryv, Moscow, Russia
3JSC Siberian Chemical Combine, Seversk, Russia
Contact person: Alexander Georgievich Tsovyanov: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To present the methods and results of studies of the factors of radiation exposure to workers involved in the manufacture of mixed uranium-plutonium nitride (MUPN) fuel at the complex experimental installations CEI-1 and CEI-2 of JSC SChC.
Material and Methods: Regularities of the formation of external exposure doses have been revealed based on the study of the dynamics of the ambient dose equivalent rate (ADER) of photon and neutron radiation at the CEI-1 and CEI-2 workplaces, as well as instrumental individual dosimetric control of the equivalent doses to workers. In order to assess the inhalation intake and possible doses from internal irradiation, studies of the physicochemical properties of radioactive aerosols were carried out.
Results: It has been found that the main sources of penetrating radiation in the premises of CEI-1 are boxes where tablets are pressed, chips and rejected tablets are crushed, as well as temporary storage of products is occurred. The highest ADER values have been measured in those boxes, where the radiation exposure was due to radioactive contamination caused by past activity, and is not associated with fabrication of MUPN fuel. A significant contribution of neutron exposure to individual doses of workers was measured, which exceeded the contribution of gamma exposure at some workplaces of the CEI-1. At CEI-2, a non-functioning exhaust ventilation pipe passing over the premises was found to be a powerful source of external radiation. This pipe contained a significant amount of radioactive material. Assessment of the contribution of gamma exposure from the ventilation pipe to the external exposure of workers reached 85% at some workplaces. Studies of the physicochemical properties of radioactive aerosols have revealed a high reactivity of MUPN compounds, leading to instant oxidation of the thoracic fraction of MUPN fuel aerosols under contact with air. The complex morphological and dispersed composition of aerosol particles in combination with a complex chemical composition caused by the aging processes of aerosols, can lead to a fundamental difference in the biokinetics of MUPN aerosols, the process of dose formation and, consequently, the degree of radiological hazard compared to those adopted in the ICRP models for U and Pu.
The results of the current radiation-hygienic research are of a preliminary nature, since the object of this research is an experimental installation, which was used to develop a new technology for the production of MUPN fuel. The instrumental and methodological approaches to assess the factors of radiation exposure to workers tested at these experimental installations, will be used in the future to conduct similar studies during the pilot industrial operation of new modules for fabricating and refurbishing of MUPN fuel.
Key words: mixed nitride uranium-plutonium fuel, radiation safety, complex experimental installation, gamma and neutron exposure, radioactive aerosols
For citation: Ilin LA, Samoylov AS., Tsovyanov AG, Shinkarev SM, Shandala NK, Gantsovsky PP, Karev AE, Kukhta BA, Simakov AV, Klochkov VN, Korenkov IP, Lyaginskaya AM, Parinov OV, Solomatin VM, Izmestyev KM. Radiation-Hygienic Investigations оf Experimental Production оf Mixed Nitride Uranium-Plutonium Fuel at JSC Schc. Part 1: Methods and Results. Medical Radiology and Radiation Safety. 2021;66(5):76-86.
DOI: 10.12737/1024-6177-2021-66-5-23-32
References
1. Rachkov V.I., Adamov E.O. Scientific and technical problems of closed nuclear fuel cycle of a two-component nuclear power plant and their solution at the project direction “Proryv”. In the collection of reports of the industry conference on the topic “Closing the fuel cycle of nuclear power based on fast neutron reactors” 11-12 October 2018, Tomsk, pp6 – 15.
2. Strategy for the development of nuclear energy in Russia in the first half of the XXI century. Basic concepts. – M.: Minatom of Russia, 2000. – 26p.
3. Project “Proryv” – technological basement for large-scale nuclear power / Adamov E.O., Alexakhin R.M., Bolshov L.A., Dedul A.V., Orlov V.V., Pershukov V.A., Rachkov V.I., Tolstoukhov D.A., Troyanov V.M. // Bulletin of the Russian Academy of Sciences. Energy. – 2015. –Vol.1, pp5 – 13.
4. Nuclear energy with natural safety: change of an outdated paradigm, criteria. / Adamov E.O., Orlov V.V., Rachkov V.I., Slesarev I.S., Khomyakov Yu.S. // Bulletin of the Russian Academy of Sciences. Energy. – 2015. – Vol.1, pp13 – 29.
5. Shultis, J. Kenneth; Richard E. Faw. p. 141, Table 6.2 // Fundamentals of Nuclear Science and Engineering. — CRC Press, 2008.
6. Physics and Fuel Performance of Reactor-Based Plutonium Disposition. Workshop Proceedings - Paris, France, 28-30 September 1998. Nuclear Energy Agency.
7. A.G. Khabakhpashev. Neutron spectrum of Po-α-O source. Atomic Energy. Vol.7, No. 1. – 1959.
8. ICRP, 2008. Nuclear Decay Data for Dosimetric Calculations. ICRP Publication 107. Ann. ICRP 38 (3).
9. Alekseev S.V., Zaitsev V.A. Nitride fuel for nuclear power: Moscow: Technosphere, 2013.
10. T. Murata et al., “Evaluation of the (α, xn) Reaction Data for JENDL/AN-2005,” JAEA-Research 2006-052 (Jul 2006) from URL https://wwwndc.jaea.go.jp/ftpnd/jendl/jendl-an-2005.html.
11. Alpha, beta and gamma spectroscopy, ed. K. Zigbana, trans. from English, in. 3 and 4, M., 1969.
12. M.D. Bondarkov, M.V. Zheltonozhskaya, A.M. Maksimenko, L.V. Sadovnikov Determination of the content of plutonium isotopes in Chernobyl samples from the characteristic Lx radiation of uranium. PROBLEMS OF NUCLEAR POWER PLANT SECURITY І CHORNOBIL VIP. 2 2005 URL: http://dspace.nbuv.gov.ua/bitstream/handle/123456789/128042/17-Bondarkov.pdf?sequence=1
13. Andersen, A. A. 1966. A Sampler for Respiratory Health Hazard Assessement. Am. Ind. Hyg. Assoc. J., 27: 160–165.
14. ICRP. Age-dependent Doses to Members of the Public from Intake of Radionuclides: Part 4, Inhalation Dose Coefficients. ICRP Publication 71.Annals of the ICRP, Vol.25, № 3-4, 1995. Elsevier Science Ltd., Oxford.
15. N.V. Baranovskaya, T.N. Ignatova, L.P. Rikhvanov Uranium and thorium in human organs and tissues, Bulletin of Tomsk State University No. 339, 2010, pp. 182-188.
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 23.12.2020.
Accepted for publication: 20.01.2021.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 39–44
Search of Predictors of Radiosensitivity in Rectal Adenocarcinoma
M.A. Vologirova1, N.N. Volchenko1, I.V. Droshneva1, I.A. Zamulaeva2, A.V. Boyko1, D.V. Sidorov1
1P.A. Hertsen Moscow Oncology Research Institute, Moscow, Russia
2A.P. Tsyb Medical Radiological Research Center, Obninsk, Russia
Contact person: Milana Aslanovna Vologirova: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To analyze a number of immunohistochemical markers as predictors of the radiosensitivity of rectal adenocarcinoma.
Material and methods: The study included 122 patients with histologically verified rectal adenocarcinoma, varying degrees of differentiation, and the stage of the tumor process I-IIIС, T2-T4b /N0-N2b/ M0, with the localization of the tumor in the lower-middle-ampullary parts of the rectum. Predictors included in the research: Ki67, р53, EGFR, Bcl2, COX2, P21, E-cadherin. Preoperative chemoradiotherapy was performed up to 48–50 Gy with the use of medications (5-FU, Cisplatin) as a radio modifiers. The analysis was carried out according to the degree of severity of therapeutic pathomorphosis (according to Mandard), a decrease in the stage before surgery.
Results: A full course of preoperative chemoradiotherapy followed by surgery was performed at 121 patients, one patient died of concomitant cardiac pathology during the break. The first degree of Mandard pathomorphosis (complete resorption) registered at 12 patients. The second degree (preservation of a few tumor cells against the background of fibrotic changes) – at 27 patients. The third degree (a large number of preserved tumor cells against the background of the predominance of fibrosis) – at 38 patients. The fourth degree (tumor cells predominate over fibrotic changes) – at 27 patients. The fifth degree (complete absence of signs of tumor regression, absence of fibrosis) – at 2 patients. A decrease in the stage of the tumor process according to the preoperative comprehensive examination registered in 114 (94.2%) patients, in 9 (7.4%) patients – there was no dynamics. During the observation period from 2006 until nowadays, 10 people are known to have died. Years in remission range from 3 months to 22 years. According to the results of multivariate and multiple regression analyses, it is possible to successfully predict the effectiveness of chemoradiotherapy, both with the use of biomarkers (Ki67, р53, EGFR, Bcl2, COX2, P21, E-cadherin), and traditional indicators (histological type, stage of the disease, gender, degree of differentiation). It turned out, that both traditional indicators and immunohistochemical indicators work equally well, regardless of each other.
Conclusion: Studied immunohistochemical predictors of radiosensitivity of rectal adenocarcinoma, allow to assess the degree of radiosensitivity or radioresistance of the tumor in each patient before the start of preoperative chemoradiotherapy by doing so, it warns us about the effectiveness or ineffectiveness of chemoradiotherapy in a specific clinical situation, which allows us to individualize the approach to treatment, choosing a more suitable treatment method for the patient: neoadjuvant chemotherapy or surgery.
Key words: locally advanced rectal cancer, preoperative chemoradiotherapy, therapeutic pathomorphosis, radiosensitivity predictors
For citation: Vologirova MA, Volchenko NN, Zamulaeva IA, Sidorov DV, Boyko AV, Droshneva IV. Search of Predictors of Ra6iosensitivity in Rectal Adenocarcinoma. Medical Radiology and Radiation Safety. 2021;66(5):39-44.
DOI: 10.12737/1024-6177-2021-66-5-39-44
References
1. Sidorov D. V., 2011. Doctoral Dissertation: "Role of Total Mesorectumectomy in the Surgical and Combined Treatment of Patients with Rectal Cancer". (In Russian.).
2. Bailey C.E., Hu C.-Y., You Y.N., et al. 2015. Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975–2010. JAMA Surg, 2015;150;1:17-22. https://doi.org/10.1001/jamasurg.2014.1756
3. Kaprin A.D., Starinsky V. V., Petrova G. V. State of Cancer Care in Russia in 2018. 2019; P. 80 (In Russian.).
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5. Rasulov A. O., 2012 Doctoral Dissertation: "Surgical Tactics after Chemoradiotherapy of Rectal Cancer". (In Russian).
6. Chernichenko M. A., 2016. PhD Thesis: "Optimization of Surgical and Combined Treatment of Patients with Lower Ampullary Rectal Cancer". P. 84, 121. (In Russian.).
7. Giralt J, Eraso A, Armengol M, Rossello J, et al. Epidermal Growth Factor Receptor of Tumor Response in Locally Advanced Rectal Cancer Patients Treated with Preoperative Radiotherapy. Int J Radiat Oncol Biol Phys 2002;54:1460-5. https://doi.org/10.1016/s0360-3016(01)01842-9.
8. Rau B, Sturm I, Lage H, Berger S, Schneider U, Hauptmann S, et al. Dynamic Expression Profile of P21waf1/Cip1 and Ki-67 Predicts Survival in Rectal Carcinoma Treated with Preoperative Radiochemotherapy. J Clin Oncol 2003;21:3391-401. https:// doi.org/10.1200/jco.2003.07.077.
9. Smith FM, Reynolds JV, Miller N, Stephens RB, Kennedy MJ. 2005. Pathological and molecular predictors of the response of rectal cancer to neoadjuvant radiochemotherapy. European Journal of Surgical Oncology: the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 01 Dec 2005, 32(1):55-64. https://doi.org/10.1016 /j.ejso.2005.09.010
10. Negri FV 1, Campanini N, Camisa R, Pucci F, Bui S, Ceccon G, Martinelli R, Fumagalli M, Losardo PL, Crafa P, Bordi C, Cascinu S, Ardizzoni A. Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy. British Journal of Cancer, 98:143–147. 2008 Jan 15. https://doi.org/10.1038/sj.bjc.6604131.
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors
Article received: 18.01.2021.
Accepted for publication: 25.03.2021.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 33–38
Sodium Deoxyribonucleate Prevents Radiation Cystitis in Uterine or Cervical Cancer Patients
P.I. Skopin1, A.A. Ivashin1, Yu.A. Skopina1, Yu.V Kozina 2, R. A. Zukov 2,3 , A.V. Siprov1, E.V. Slepov2
1N.P. Ogarev National Research Mordovia State University, Saransk, Russia.
2A.I. Kryzhanovsky Krasnoyarsk Regional Clinical Oncological Dispensary, Krasnoyarsk, Russia
3V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia
Contact person: Artem Aleksandrovich Ivashin: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Results: To develop a method for reducing the frequency and severity of early radiation reactions in patients with cancer of the uterus or cervix.
Material and methods: We analyzed the results of treatment of 60 patients with cancer of the uterus and cervix, patients received a postoperative course of external beam radiotherapy combined with the intramuscular administration of the Derinat® radioprotector (sodium deoxyribonucleate); in the second arm, they received a postoperative course of external beam radiotherapy and standard therapy in case of radiation cystitis. The assessment of radiation reactions severity was performed with the EORTC QLQ-C30 criteria, WBC count, IPSS scale, urine analysis and cystoscopic examination evaluated with the developed by us scale.
Results: Evaluation of the quality of life in patients with cervical or uterine cancer at the final stage of treatment using the IPSS scale showed that in the arm of patients with sodium deoxyribonucleate, there was a 30.4 % (p> 0.05) decrease in the symptoms of urinary disorders. The use of the radioprotector sodium deoxyribonucleate also statistically significantly reduced the incidence of radiation cystitis by 73 %. According to cystoscopy, the total bladder injury score at the end of treatment was 147 % lower. The number of leukocytes in the urine analysis at the end of treatment was 116.3 % lower (p≤0.01) in those who received sodium deoxyribonucleate
Conclusion: The data obtained indicate the radioprotective efficacy of sodium deoxyribonucleate and make it possible to recommend its intramuscular administration to patients with cancer of the uterus and cervix against the background of external beam radiation therapy to reduce the frequency and severity of acute radiation cystitis in patients with cancer of the uterus or cervical cancer receiving external beam radiation therapy.
Key words: radiation cystitis, uterine cancer, cervical cancer, sodium deoxyribonucleate
For citation: Skopin PI, Ivashin AA, Skopina Yu.A, Kozina YuV, Zukov R A. Siprov AV, Slepov EV. Sodium Deoxyribonucleate Prevents Radiation Cystitis in Uterine or Cervical Cancer Patients. Medical Radiology and Radiation Safety. 2021;66(5):30-35.
DOI: 10.12737/1024-6177-2021-66-5-33-38
References
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6. Jereczek-Fossa BA, Badzio A, Jassem J. Factors Determining Acute Normal Tissue Reactions During Postoperative Radiotherapy in Endometrial Cancer: Analysis of 317 Consecutive Cases. Radiother. Oncol. 2003;68;1:33–39.
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9. Sycheva IV, Pasov VV, Kurpesheva AK. Conservative Methods of Treatment of Local Radiation Injuries Formed as a Result of Combined Radiotherapy and Brachytherapy of Prostate Cancer. Siberian Journal of Oncology. 2012;53;5:57-60 (In Russian).
10. Kulaev MT, Almyashev AZ, Meltsaev GG, Shchukin S.A. External1. Application of Derinat in the Treatment of Radiation Ulcers and Malignant Tumors of Visible Localizations. Creative Surgery and Oncology. 2009;1:35-39 (In Russian).
11. Zukov RA, Kozina YV, Kozin VA, Slepov EV. Optimization of Radiation Therapy in Patients with Prostate Cancer. Siberian Medical Review. 2018;2:110-105. DOI: 10.20333/2500136-2018-2-100-105 (In Russian).
12. Minaev NN, Ivanova MN, Bugrimov DY, Klimovich AA. Clinical Efficacy of Agonist Toll-Like Receptor 9 on the Process of Reparations after Loop Conization (LEEP) of the Cervix. Journal of Obstetrics and Women’s Diseases. 2016;5:101-112. DOI: 10.17816/JOWD655101-112 (In Russian).
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors
Article received: 17.02.2021.
Accepted for publication: 20.04.2021.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 45–49
Patientoriented Algorithm for the X-ray Therapy Cabinet of Oncology Dispensary
J.A. Zuenkova1, D.I. Kicha1, A.Yu. Abramov1, Y.G. Buynova2, L.M. Klisova2
1Peoples Friendship University of Russia, Moscow, Russia
2City Clinical Oncology Dispensary, Saint-Petersburg, Russia
Contact person: Zuenkova Yuliya Aleksandrovna: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Results: IIntroduction: Superficial X-ray therapy is a common treatment of non-melanoma skin cancer with a high incidence worldwide. Interrupting the course of radiation therapy can negatively affect patient survival and treatment results. Low treatment adherence may be associated with a lack of a patient-centered approach and ineffective communications. The original study shows that patients undergoing X-ray therapy for cancer may have different needs. Based on the study results an algorithm for a patient-oriented approach has been developed for the X-ray cabinets.
Purpose: To develop a patient-oriented algorithm of the X-ray therapy room to address the issues of increasing patient satisfaction and forming their adherence to treatment. The objectives of the study included studying and detailing the needs of the patients who passed the X-ray therapy and to develop the patient-oriented algorithm for the X-ray therapy room.
Material and methods: The study of the patient's values was carried out from 2019 to 2020 by interviewing using open-ended questions to find out the deep motives and beliefs of patients. The study was based on Milton Rokich’s (2005) model of value orientations, which was adapted to the objectives of the study.
Results: The study included 116 patients undergoing treatment with the X-ray therapy at the City Clinical Oncology Dispensary. As a result of the study, the following patient needs were identified: clinical outcome of the procedure 111 (96 %), safety of treatment and adverse reactions 106 (91 %), cosmetic outcome 53 (46 %), convenience of the treatment schedule 42 (36 %), painlessness of the procedure 39 (34 %), the ability to lead a normal lifestyle 27 (23 %), comfortable conditions for the procedure 16 (14 %), financial costs associated with treatment 10 (9 %), preservation of organ function 4 (3 %). On the basis of the data obtained, a patient-oriented algorithm for the X-ray therapy was developed, including a communication plan with the patient. The study results clearly demonstrate that even with the same disease and condition, patients may have different priorities hat need to be considered to improve patient experience and adherence to treatment.
Conclusion: Radiation treatment decision-making based on the patients values is important for the development of the patient-centered management in oncology since this directly affects patients’ adherence to treatment. Exploring the values and needs of patients is an opportunity to influence and improve the metrics of the patient experience. Due to the mass incidence of non-melanoma skin cancer, the introduction of patient-centered approaches is an important part of patient satisfaction and increase of patients adherence to the treatment.
Key words: quality of medical care, value-based healthcare, X-ray therapy, skin cancer
For citation: Zuenkova JA, Kicha DI, Abramov AYu., Buynova YG, Klisova LM. Patientoriented Algorithm for the X-ray Therapy Cabinet of Oncology Dispensary. Medical Radiology and Radiation Safety. 2021;66(5):45-49.
DOI: 10.12737/1024-6177-2021-66-5-45-49
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors
Article received: 14.04.2021.
Accepted for publication: 27.05.2021.