JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 5. P. 14-22
RADIATION MEDICINE
N.A. Metlyaeva
Adverse Prognosis of Multifocal Atherosclerosis of Patient, who Transferred Acute Radiation Disease I Degree of Severity
Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Assessment of psychophysiological adaptation of patient B.A.I. with the heavy psychosomatic and all-somatic cardiovascular and cerebrovascular pathology, transferred an acute radiation disease (ARS) of I degree, from the general evenly gamma-beta radiation according to datas features of his individual mental adaptation and the periods of a staginess of mental adaptation.
Material and methods: B.A.I., 1940 year of birth was suffered ARS I degree of severity from uniform gamma-beta radiation. The total dose to the body, according to electro-paramagnetic resonance (EPR) of tooth enamel from 2001, was 0.77 ± 0.25 Gy, on neutrophil — 1,2 Gy, in the culture of cells — 0,7 Gy For 25 years was examined and treated about the acute and long-term effects of ARS I degree of severity and severe progressive cardiovascular and cerebrovascular pathology. Thus, at B.A.I. in dynamics started being formed and progress, the so-called, multifocal atherosclerosis (MFA).
Results: B.A.I. during the first inspection 16.05.1986 and at supervision within 25 years in dynamics (2001, 2002, 2009, 2010) the aspiration to look in favorable light was a leading resistant tendency when testing, showing in answers strict observance even insignificant rules and social norms (L 71.6 scale), subdepressive and disturbing-depressive tendencies (scale 2D 71.2, 9Ma 50.0 T-points, F1 5.1–7.7–8.1 walls). Registration of B.A.I. of the changes overstepping the bounds of population norm, in the form of an affective rigidity (scale of 6Pa 71.0), psychasthenia (a scale of 7Pt 71.8) and original thinking (scale of 8Sch 68.8), along with the indicators of characterizing a neurologic triad (scales 1Hs, 2D, 3Hy), indicate violation not only neurologic, but also psychological adaptation, subdepressive and disturbing and depressive tendencies (scale 2D 71.2, 9Ma 50.0 T-points, F1 5.1–7.7–8.1 walls), caused by weight of all-somatic and psychosomatic pathology.
Conclusions: The subdepressive and disturbing-depressive syndrome in B.A.I. was independent risk factor of development of multifocal atherosclerosis; Features of development of all-somatic and psychosomatic pathology in B.A.I. are based on a combination of genetic prerequisites, environment influences (the stress caused by accident on the ChNPP) and social factors, influencing on him during a course of life, especially during early socialization. Thus at development of psychosomatic frustration the combination of feature of the mental reaction connected with the personal characteristic and special relationship between mental (stress) and physiological (somatic) by aspects of reaction which led to metabolism violation, to aging, decrease in adaptation opportunities of an organism and development age — dependent pathology took place.
Key words: acute radiation disease, ionizing radiation, adaptation, atherosclerosis, hypertensive disease, ischemic heart disease, cerebrovascular arteriosclerosis, obliterating endoangiitis
Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 5. P. 5-13
RADIATION SAFETY
A.V. Panov, V.V. Ponomarenko, E.V. Marochkina
Variations in the Role of Radionuclide Containing Foodstuffs in Dose Formation from Internal Irradiation of the Population in Different Periods after the Chernobyl NPP Accident
Russian Institute of Agricultural Radiology and Agroecology of RAAS, Obninsk, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Estimation of regularities of variations in the contribution of the main dose-forming foodstuffs contaminated by radionuclides to the dose formation from internal irradiation of the population in the Chernobyl affected area 20 years after the accident and analysis of factors responsible for dose formation in humans.
Material and methods: A study was performed in the two regions of Russia most affected after the Chernobyl accident. In the both regions rural settlements were investigated Krasnogorsk district in the Bryansk region and Plavsk district in the Tula region. These are distinguished in both levels of 137Cs contamination and soil properties. For the settlements of studied areas, module calculations of level 137Cs contamination of agricultural and natural food products, consumed by the residents after the Chernobyl accident, from 1990 to 2010 are executed. The dynamics of 137Cs contamination of food products, as well as dose to the residents from internal exposure during 20 years after the accident without application of countermeasures were evaluated.
Results: Based on the obtained of modular data, changes in the radioecological situation in the affected rural settlements were analyzed. Regularities were described of 137Cs contamination of farm and natural food products, as well as peculiar features of dose formation from internal exposure in various periods after the Chernobyl accident. The estimates took into account radioecological, regulatory and time factors.
Conclusion: Based on the model calculations, significant variations in time of the ratio contribution of agricultural and natural foods in the internal dose of the population in different soil types are shown. Thus, 4 years after the accident, on light (sandy, light and medium-loam) soils the main contributor to the internal dose to the population was agricultural produce — 65 % (milk — 35 %), mushrooms — 35 %. By 2000, the contribution of the mushroom component increased to 50 %. On heavy (clay) soils, in 1990, the contribution of farm products to internal exposure of the residents amounted to 80 % (milk — 45 %). To date, the contribution to the internal dose of mushrooms on these soils grew to 30 %. These features are explained by different rate of decline with years of 137Cs transfer factors from light and heavy soils to agricultural and natural food products.
Key words: Chernobyl accident, internal exposure doses, specific radionuclide activity in foodstuffs, 7Cs transfer factor
Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 6. P. 54-62
NUCLEAR MEDICINE
V.V. Krylov, T.U. Kochetova
Radionuclide Therapy with Rhenium-188-HEDP for the Treatment of Patients with Bone Metastases Medical Radiology Centre of Hertsen FMRC MH RF
Medical Radiology Centre of Hertsen FMRC MH RF. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Radionuclide therapy is one of the effective treatment modalities to palliate painful bone metastases, improving this kind of therapy is an important task. 188Re-HEDP is one of safe and effective bone-seeking radiopharmaceuticals; moreover, it is very convenient in clinical practice. It has been used in the world practice since 1998; clinical studies of Russian analogue were finished in 2013. 188Re is a powerful β-emitter, presence of γ-rays allows facile visualization of its distribution in human body using simple bone scan. 188Re is convenient because it can be obtained from in-house 188W/188Re generator. Multiple clinical studies confirmed that 188Re-HEDP is effective and safe in dosage of 2.6–3.3 GBq. The main side effect is decrease of platelet and white blood cell count grade I–II, 3–5 weeks after injection. Its efficacy is similar to other bone-seeking radiopharmaceuticals and can attain 80 % after single injection. Prospective randomized trial demonstrated benefits of repeated bone targeted therapy in hormone-resistant prostate cancer patients. The group of patients received two injections with 8 weeks interval showed increase in palliative efficacy from 60 % to 90 %; furthermore, there was benefit in overall survival (12.7 months compared to 7.0 months in the single injection group) and time to progression (7.0 months compared to 2.3 months). In addition, there was antitumoral effect, in repeated treatment group more often lasting 50 % PSA decrease (39 % and 7 % respectively) and bone scan regression was found. 188Re-HEDP can be affective in combination with other treatment modalities. Some treatments protocols of serial chemotherapy and 188Re-HEDP radionuclide therapy were designed. Further investigation may show the influence of these schedules on patients’ survival. In conclusion, 188Re-HEDP may become useful and convenient treatment modality in Russian clinical practice.
Key words: bone metastases, radionuclide therapy, rhenium-188 HEDP, pain syndrome, palliation therapy
Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 6. P. 63-78
REVIEW
l.A. Souvorova
Normal Blood and its Potential for Comparative Evaluation of Low-Intensity Radiation Factors Impact
Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Standard blood counts meeting the criteria for developing standards (examination of large groups of patients, matched by age, gender, nationality, occupation, season etc.) and mathematical processing adequate to the task are required to asses the impact of low-intensity radiation factors upon the hematopoietic system (a single external radiation exposure to < 1Gy, chronic radiation exposure to doses more than maximum permissible) and the effects of acute radiation disease. Comparative evaluation of blood values to asses the impact of occupational factors should be adjusted to fluctuations of 10–12 values using blood deterioration ratio and leucogram entropy. To analyse and compare the impact of different low intensity factors upon hemapoiesis its advisable to develop regional standards.
Key words: hematologic norm, low intensity radiation factors, practical applications
Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 6. P. 49-53
RADIATION THERAPY
O.K. Kurpeshev
Capabilities of Radiation Therapy in Palliative Treatment of Malignant Liver Tumors
Medical Radiology Centre of Hertsen FMRC MH RF. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
CONTENT
In this review, the outcomes and future prospects of different methods of radiation therapy in palliative treatment of primary and secondary malignant liver tumors have been assessed.
Key words: radiation therapy, malignant tumors of the liver