JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 1. P. 5–28
RADIATION SAFETY
B.A. Napier1, M.O. Degteva2, N.B. Shagina2, L.R. Anspaugh3
Uncertainty Analysis for the Techa River Dosimetry System
1. Pacific Northwest National Laboratory, Richland, WA, USA; 2. Urals Research Center for Radiation Medicine, Chelyabinsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 3. University of Utah, Salt Lake City, UT, USA
Abstract
Purpose: Estimation of uncertainties in the doses for the members of the Techa River Cohort (TRC) with a two-dimensional Monte Carlo approach.
Material and methods: In order to provide more accurate and precise estimates of individual dose (and thus more precise estimates of radiation risk) for the members of the TRC, the Techa River Dosimetry System used. The deterministic version of the improved dosimetry system TRDS-2009D was basically completed in April 2009. Recent developments in evaluation of dose-response models in light of uncertain dose have highlighted the importance of different types of uncertainties in the development of individual dose estimates. Thus, the TRDS-2009 parameters were analyzed accordantly. These include uncertain parameters that may be either shared (common to some or all individuals) or unshared (a unique value for each person whose dose is to be estimated) within the dosimetric cohort. The nature of the type of uncertainty may be aleatory (random variability of true values due to stochastic processes) or epistemic (due to lack of complete knowledge about a unique quantity). Finally, there is a need to identify whether the structure of the errors is either related to measurement (the estimate differs from the true value by an error that is stochastically independent of the true value; frequently called classical uncertainty) or related to grouping (the true value varies from the estimate by an error that is random and is independent of the estimate; frequently called Berkson uncertainty).
Results: An approach has been developed that identifies the nature of the various input parameters and calculational methods incorporated in the Techa River Dosimetry System (based on the TRDS-2009D implementation), and a stochastic calculation model has been prepared to estimate the uncertainties in the dose estimates. This article reviews the concepts of uncertainty analysis, the equations, and input parameters, and then identifies the authors’ interpretations of their general nature.
Conclusions: It presents the approach selected so that the stochastic, Monte-Carlo, implementation of the dosimetry system TRDS-2009MC provides useful information regarding the uncertainties of the doses.
Key words: uncertainty analysis, radiation dosimetry, Techa River
REFERENCES
- Krestinina L.Yu., Preston D.L., Ostroumova E.V. et al. Protracted radiation exposure and cancer mortality in the Techa River Cohort. Radiat. Res., 2005. Vol. 164. P. 602–611.
- Krestinina L.Yu., Davis F., Ostroumova E.V. et al. Solid cancer incidence and low-dose-rate radiation exposures in the Techa River Cohort: 1956–2002. Intl. J. Epidemiol. 2007. Vol. 36. P. 1038–1046.
- Krestinina L., Preston D.L., Davis F.G. et al. Leukemia incidence among people exposed to chronic radiation from the contaminated Techa River, 1953–2005. Radiat. Environ. Biophys., 2009. Vol. 49. P. 195–201.
- Degteva M.O., Vorobiova M.I., Kozheurov V.P. et al.Dose reconstruction system for the exposed population living along the Techa River. Health Phys., 2000. Vol. 78. P. 542–554.
- Degteva M.O., Kozheurov V.P., Tolstykh E.I. et al. The Techa River Dosimetry System: Methods for the reconstruction of internal dose. Health Phys., 2000. Vol. 79. P. 24–35.
- Degteva M.O., Vorobiova M.I., Tolstykh E.I. et al. Development of an improved dose reconstruction system for the Techa River population affected by the operation of the Mayak Production Association. Radiat. Res., 2006. Vol. 166. P. 255–270.
- Degteva M.O., Shagina N.B., Vorobiova M.I. et al. Reevaluation of waterborne releases of radioactive materials from the Mayak Production Association into the Techa River in 1949–1951. Health Phys., 2012. Vol. 102. P. 25–38.
- Degteva M.O., Tolstykh E.I., Vorobiova M.I. et al. Structure of the revised Techa River Dosimetry System: Exposure pathways and system databases. Chelyabinsk and Salt Lake City: Urals Research Center for Radiation Medicine and University of Utah; Combined report for Milestones 20 and 21, Part 2. 2009.
- Stram D.O., Kopecky K.J. Power and uncertainty analysis of epidemiological studies of radiation-related disease risk in which dose estimates are based on a complex dosimetry system: some observations. Radiat. Res., 2003. Vol. 160. P. 408–417.
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- National Council on Radiation Protection and Measurements (NCRP). A Guide for Uncertainty Analysis and Dose and Risk Assessments Related to Environmental Contamination, NCRP Commentary No. 14. Bethesda, Maryland: NCRP, 1996.
- Hofer E. How to account for uncertainty due to measurement errors in an uncertainty analysis using Monte Carlo simulation. Health Phys., 2008. Vol. 95. P. 277–290.
- Carroll R.J., Ruppert D., Stefanski L.A. et al. Measurement Errors in Non-Linear Models: A Modern Perspective. Second Edition. Vol. 105. Chapman & Hall/CRC. 2006.
- National Council on Radiation Protection and Measurements (NCRP). Uncertainties in the Measurement and Dosimetry of External Radiation, NCRP Report No. 158. Bethesda, Maryland: NCRP, 2007. 567 p.
- National Council on Radiation Protection and Measurements (NCRP). Uncertainties in Internal Radiation Dose Assessment, NCRP Report No. 164. Bethesda, Maryland: NCRP, 2010.
- International Atomic Energy Agency (IAEA). Evaluating the Reliability of Predictions Made Using Environmental Transfer Models. IAEA Safety Series No. 100, STI/PUB/835. Vienna, Austria: IAEA, 1989. 106 p.
- National Council on Radiation Protection and Measurements (NCRP). Radiation Dose Reconstruction: Principles and Practices, NCRP Report No. 163. Bethesda, Maryland: NCRP, 2010.
- Li Y., Guolo A., Hoffman F.O. et al. Shared uncertainty in measurement error problems, with application to Nevada Test Site fallout data. Biometrics, 2007. Vol. 63. P. 1226–1236.
- Napier B.A., Shagina N.B., Degteva M.O. et al. Preliminary uncertainty analysis for the doses estimated using the Techa River Dosimetry System – 2000. Health Phys., 2001. Vol. 81. P. 395–405.
Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 69-78
NUCLEAR MEDICINE
A.B. Bludov, Ya.A. Zamogilnaya, A.S. Nered, S.V. Shiryaev, N.V. Kochergina, L.E. Rotobelskaya
Diagnostic Value of Radionuclide Bone Scans in the Evaluation of the Preoperative Chemotherapy of Bone Sarcomas
N.N. Blokhin Russian Cancer Research Center of RAMS, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To determine the diagnostic value of the radionuclide bone scans in the evaluation of the effectiveness of preoperative chemotherapy in patients with bone sarcomas on different diagnostic stages.
Material and methods: We analyzed the data of 52 patients with bone sarcomas (mostly with osteosarcoma (50 patients), which composed 96 % of the cases). All patients underwent bone scan examination with 99mTc-Technefor. The patients were examined before, in the middle and at the end of the preoperative chemotherapy course.
Results: The sensitivity (predilection of Grade III–IV pathologic response) of the radionuclide bone scans in the middle of the preoperative chemotherapy (after 2–3 cycles) was 87 %, the specificity (predilection of Grade I-II pathologic response) was 69 %, accuracy – 79 %. At the end of the preoperative treatment, on the second diagnostic stage, the values of the sensitivity, specificity and accuracy increased up to 90, 73 and 83 %, correspondingly.
Conclusion: Bone radionuclide bone scans with 99mTc-Tehnefor is a highly effective method in assessing of preoperative chemotherapy in patients with bone sarcomas.
Key words: osteosarcoma, chemotherapy, bone scintigraphy, 99mTc-Technefor
Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 53-61
RADIATION THERAPY
L.I. Musabaeva1, V.A. Lisin1,2, Zh.A. Startseva1, O.V. Gribova1, V.V. Velikaya1, A.A. Melnikov1
Neutron Therapy on U-120 Cyclotron
1. Cancer Research Institute, Siberian Branch of the RAMS, Tomsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. National Research Tomsk Polytechnic University
ABSTRACT
The review is devoted to the 30-year neutron therapy experience in cancer treatment at the Tomsk Cancer Research Institute. In 1983, the Institute of Nuclear Physics affiliated to the Tomsk Polytechnic University was the first in Russia to perform radiation therapy with fast neutrons for cancer patients. Neutron therapy at the initial stage included the formation of the therapeutic fast neutron beam with the average energy of 6.3 MeV, dosimetric and radiobiological studies, clinical trials and accumulation of the own experience in the treatment of resistant tumors with fast neutrons. Efficacy of new methods of neutron and concurrent neutron-photon therapy, optimal regimens of combined modality treatment and independent radiation therapy were studied. The comprehensive programme on the prevention and treatment of acute radiation-induced complications and radiation damages to normal tissues and critical organs was developed.
Content
Introduction
Purpose of the study
Dosimetric and radiobiological studies
Clinical trials
Patterns of tumor reoxygenation in fast neutron therapy
Parotid salivary gland
Thyroid cancer
Neutron therapy for patients with locally advanced T2–4N0–2M0 breast cancer
Pathological tumor response to preoperative neutron therapy
Fast neutrons in the treatment of locally recurrent breast cancer
Cytogenetic studies in cancer patients who received neutron therapy
Conclusion
Key words: therapeutic channel, resistant tumor forms, neutron Therapy
Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 62-68
RADIATION THERAPY
O.P. Trofimova, S.I. Tkachev, Z.P. Mikhina, Yu.I. Pryamikova, N.P. Shipilina, O.S. Zaichenko, I.V. Kolyadina, A.M. Malishev
The Addition of a Boost Dose on the Primary Tumor Bed after Breast Conserving Treatment for Breast Cancer Patients
N.N. Blokhin Russian Cancer Research Center of RAMS, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To increase the radiation therapy efficacy in breast cancer patients.
Material and methods: Investigation includes 438 patients with verified breast cancer. All patients received breast conserving treatment within period of 2000–2012, including breast conserving surgery ± systemic therapy – 58 pt.; breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) – 313 pt.; breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) + boost dose on the primary tumor bed (10–16 Gy) – 72 pt.
Results: Local relapse after breast conserving surgery ± systemic therapy – 24.5 %; after breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) – 5.8 % (p < 0.05); after breast conserving surgery ± systemic therapy+ whole breast irradiation (50 Gy) + boost dose on the primary tumor bed (10–16 Gy) – 2.7 %.
Conclusion: The addition of a boost dose on the primary tumor bed after breast conserving treatment for breast cancer patients decrease local recurrences.
Key words: radiotherapy, breast cancer, local recurrens
Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 46-52
DIAGNOSTIC RADIOLODGY
A.A. Levitov, V.I. Krasnyuk, E.V. Sitnikova, A.P. Dunaev
The Effectiveness of X-ray Linear Digital Tomosynthesis in Visualization of Focal Lesions in Lungs, Suspected Metastases, Comparing With Digital Radiography in Patients with Breast Cancer
Burnasyan Federal Medical Biophysical Center of the FMBA of Russia, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Comparison of the effectiveness of the Χ-ray digital linear tomosynthesis and digital Χ-ray in visualization of focal lesions in the lung, suspicious for metastasis in patients with verified by histology breast cancer.
Material and methods: Radiographic studies were performed in 47 patients with verified by histology breast cancer of different stages using two Χ-ray methods: digital radiography and digital linear tomosynthesis.
Results: Focal lesions in the lung suspicious for metastasis were identified with digital radiography of the chest in 8.5 % of surveyed patients only; against 29.8 % – with the use of digital linear tomosynthesis. Conclusion: Considering the data obtained in the course of our study, it is advisable to use a digital linear tomosynthesis as a more effective Χ-ray method for the focal lung lesions’ verification in patients with breast cancer.
Key words: linear digital tomosynthesis, digital radiography, lung metastases, breast cancer