JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety, 2016, Vol. 61. No. 5. P. 13-26

RADIATION EPIDEMIOLOGY

V. Azizova1, E.S. Grigoryeva1, R. Haylock2, M.V. Bannikova1, M.B. Moseeva1

Risk of Incidence and Mortality from Ischemic Heart Disease in the Cohort of Workers with Chronic Occupational Exposure

1. Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Public Health England, Chilton, UK

ABSTRACT

Purpose: Assessment of incidence and mortality risk from ischemic heart disease (IHD) in relation to radiation (external gamma- and internal alpha-exposure) and non-radiation factors (gender, age, smoking, alcohol consumption, hypertension, increased body mass index).

Material and methods: IHD risk was studied in the cohort of workers of the nuclear enterprise (22377 workers, 25 % - females) with chronic occupational exposure. Relative risks and excess relative risks per unit dose (1 Gray) were calculated based on maximum likelihood using AMFIT module of the EPICURE software. Dose estimates used in analyses were provided by an updated ‘Mayak Worker Dosimetry System-2008’.

Results: A significant linear association of IHD incidence risk with total dose from external gamma-rays was observed after having adjusted for non-radiation factors and dose from internal radiation (ERR/Gy = 0.10; 95 % CI: 0.04, 0.17). No significant association of IHD mortality risk was revealed after having adjusted for non-radiation factors and dose from internal alpha-radiation (ERR/Gy = 0.06; 95 % CI: < 0, 0.15). No association of IHD incidence risk with total absorbed dose from internal alpha-radiation to the liver after having adjusted for non-radiation factors and external gamma-dose (ERR/Gy = 0.02; 95 % CI: n/a, 0,10). Statistically significant linear association of IHD mortality risk with total absorbed dose from internal alpha-radiation to the liver was revealed after having adjusted for non-radiation factors and external gamma-dose (ERR/Gy = 0.21; 95 % CI: 0.01, 0.58).

Conclusion: This study provides strong evidence of the association of the ischemic heart disease incidence risk with external gamma-ray exposure and some evidence of the association of the mortality risk for ischemic heart disease with internal alpha-radiation exposure.

Key words: risk, mortality, incidence, ischemic heart disease, Mayak PA, gamma-ray, alpha-radiation, occupational exposure

REFERENCES

  1. Doklad ekspertov VOZ. Zheneva: VOZ. 2008. 76 p. (In Russ.).
  2. Oganov R.G. Demograficheskie tendentsii v Rossiiskoi Federatsii: vklad boleznei sistemy krovoobrashcheniya. Kardiovaskulyarnaya terapiya i profilaktika. 2012. No. 1. P. 5-10. (In Russ.).
  3. Oganov R.G., Maslennikova G.Ya. Epidemiyu serdechno-sosudistykh zabolevanii mozhno ostanovit' usileniem profilaktiki. Profilakticheskaya meditsina. 2009, Vol. 12. No. 6. P. 3-7. (In Russ.).
  4. Yusuf S., Hawken S., Ounpuu S. et al. INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART Study): case-control study. Lancet. Vol. 364. No. 9438. P. 937-952.
  5. Azizova T.V., Muirhead C.R., Druzhinina M.B. et al. Cardiovascular Diseases in the Cohort of Workers First Employed at Mayak PA in 1948-1958. Radiat. 2010. No. 174. P. 155-168.
  6. Azizova T.V., Muirhead C.R., Moseeva M.B. et al. Ischemic heart disease in nuclear workers first employed at the Mayak PA in 1948-1972. Health Phys. 2012. 103. No. 1. P. 3-14.
  7. Simonetto C., Azizova T.V., Grigoryeva E.S. et al. Ischemic heart disease in workers at Mayak PA: Latency of incidence risk after radiation exposure. PLoS ONE. 2014. 9. No. 5. P. e96309.
  8. Moseeva M.B., Azizova T.V., Grigorieva E.S. et al. Risk of circulatory diseases among Mayak PA workers with radiation doses estimated using the improved Mayak Workers Dosimetry System 2008. Radiat. Biophys. 2014. Vol. 53. No. 2. P. 469-477.
  9. Azizova T.V., Day R.D., Wald N. et al. The “Clinic” medical-dosimetric database of Mayak production association workers: structure, characteristics and prospects of utilization. Health Phys. 2008. 94. P. 449-458.
  10. Rossiiskaya Federatsiya. Zakony. Federal'nyi zakon o personal'nykh dannykh: ot 27 iyulya 2006 g. № 152-FZ. Rossiiskaya gazeta. Federal'nyi vypusk 4131 ot 29.07.06. (In Russ.).
  11. Koshurnikova N.A., Shilnikova N.S., Okatenko P.V. Characteristics of the cohort of workers at the Mayak nuclear complex. Radiat. Res. 1999. Vol. 152. No. 4. P. 352-363
  12. Mezhdunarodnaya statisticheskaya klassifikatsiya boleznei i problem, svyazannykh so zdorov'em. Desyatyi peresmotr. V 3 t. Vol 1. Moscow: Meditsina. 1995. 698 p. (In Russ.).
  13. Vasilenko E.K., Scherpelz R.I., Gorelov M.V. et al. External Dosimetry Reconstruction for Mayak Workers. AAHP Special Session Health Physics Society Annual Meeting. Available from: http://www.hps1.org/aahp/public/AAHP_Special_Sessions/2010_Salt_Lake_City/pm-1.pdf. 2010 (10.12.2010).
  14. Khokhryakov V.V., Khokhryakov V.F., Suslova K.G. et al. Mayak Worker Dosimetry System 2008 (MWDS-2008): Assessment of internal alpha-dose from measurement results of plutonium activity in urine. Health Phys. 2013. 104. No. 4. P. 366-378.
  15. Preston D., Lubin J., Pierce D., McConney M. EPCURE Users Guide. Seattle, WA: Hirosoft. 1993. 330 p.
  16. Nemtsov A.V., Terekhin A.T. Serdechno-sosudistaya smertnost' i potreblenie alkogolya v Rossii. Profilakticheskaya meditsina. 2008. No. P. 25-30. (In Russ.).
  17. Preston D.L., Shimizu Y., Pierce D.A. et al. Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997. Radiat. Res. 2012. No. 178. AV146-AV172.
  18. Shimizu Y., Kodama K., Nishi N. et al. Radiation exposure and circulatory disease risk: Hiroshima and Nagasaki atomic bomb survivor data, 1950-2003. BMJ. 2010.Vol. 340. b5349
  19. McGeoghegan D., Binks K., Gillies M. et al. The non-cancer mortality experience of male workers at British Nuclear Fuels plc, 1946-2005. Int. J. Epidemiol. Vol. 37. P. 506-518.
  20. Vrijheid M., Cardis E., Ashmore P. et al. Mortality from diseases other than cancer following low doses of ionizing radiation: results from the 15-country study of nuclear industry workers. Int. J. Epidemiol. Vol. 36. P. 1126-1135.
  21. Muirhead C.R., O’Hagan J.A., Haylock R.G.E. et al. Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers. Brt. J. Cancer. Vol. 100. P. 206-212.
  22. Metz-Flamant C., Laurent O., Samson E. et al. Mortality associated with chronic external radiation exposure in the French combined cohort of nuclear workers. Occup. Med. 2013. Vol. 70. P. 630-638.
  23. Zablotska L.B., Little M.P., Cornett R.J. Potential increased risk of ischemic heart disease mortality with significant dose fractionation in the Canadian Fluoroscopy cohort study. Amer. J. Epidemiol. Vol. 179. No. 1. P. 120-131.
  24. Yamada M., Wong F.L., Fujiwara S. et al. Non-cancer disease incidence in atomic bomb survivors, 1958-1998. Radiat. 2004. Vol. 161. P. 622-632.
  25. Ivanov V., Maksioutov M.A., Chekin S.Y. et al. The risk of radiation-induced cerebrovascular disease in Chernobyl emergency workers. Health Phys. 2006. Vol. 90. P. 199-207.
  26. Little M.P., Tawn E.J., Tzoulaki I. et al. Review and meta-analysis of epidemiological associations between low/moderate doses of ionizing radiation and circulatory disease risks and their possible mechanisms. Radiat. Biophys. 2010. Vol. 49. No. 2. P. 139-153.
  27. Little M.P. A review of non-cancer effects, especially circulatory and ocular diseases. Radiat. Biophys. 2013. Vol. 52. No. 4. P. 435-449.
  28. Borghini A., Gianicolo E.A.L., Picano E., Andreassi M.G. Ionizing radiation and atherosclerosis: Current knowledge and future challenges. Elsevier. No. 230. P. 40-47.
  29. United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). Effects of Ionizing Radiation. UNSCEAR 2006 Report to the General Assembly, with scientific annexes. United Nations: New York. 2008.

For citation: Azizova TV, Grigoryeva ES, Haylock R, Bannikova MV, Moseeva MB. The Risk of Incidence and Mortality from Ischemic Heart Disease in the Cohort of Workers with Chronic Occupational Exposure. Medical Radiology and Radiation Safety. 2016;61(5):13-26. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 5. P. 5-12

RADIATION MEDICINE

N.A. Isaeva, F.S. Torubarov, Z.F. Zvereva, S.N. Lukyanova, E.A. Denisova

Bioelectric Activity of the Brain of Employees of the Novovoronezh and Beloyarsk NPPs at Different Levels of Psychophysiological Adaptation to the Conditions of Their Work

A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: The analysis of EEG-indicators at different levels of psychophysiological adaptation (PFA) as its integrated characteristic, as its states: mental (PS), psychophysiological (PFS) and physiological (FS).

Material and methods: 88 employees of nuclear power plants of Russia are examined (43.1±9.4 years, 75 men). Psychophysiological examination was conducted by means of hardware and software complex “Agrarian and Industrial PFS-Control”. Techniques were used: “Technique of multilateral research of the personality”, “16-factorial personal questionnaire”, “The Raven’s Progressive Matrices”, “Level of subjective control”, “Simple visual and motor reaction”, “Difficult visual and motor reaction”, “Reaction to a moving subject”, “Variability of a warm rhythm”. Carried in parallel out the visual analysis of EEG by the method E.A. Zhirmunskaya. Existence of abnormal signs were estimated: EEG of the IV type, instability of a pattern during background record, a high index of low-frequency β-activity, flashes of bilateral and synchronous waves. The comparative statistical assessment of various groups was carried out, using parametrical and nonparametric criteria according to the BIOSTAT program.

Results: At the PFA low level 4 above-stated abnormal signs are revealed in comparison with high corresponded to the low level of mental state: EEG of the IV type and instability of dynamics. The PFS low level (in comparison with high) correlated with EEG indicators: IV type, instability of dynamics, flashes of bilateral and synchronous waves. At the FS low level were registered: EEG of the IV type, instability of dynamics, a high index β1-activity, flashes of bilateral and synchronous waves.

Conclusions: 1) PFA determined by psychophysiological tests is reflected in indicators of bioelectric activity of the brain. 2) At the PFA low level character of abnormal EEG signs allows to assume existence of functional deviations at the CNS different levels. 3) The greatest neurophysiological violations are revealed in persons with the low level of physiological state.

Key words: employees of the NPP, EEG, psychophysiological adaptation

REFERENCES

  1. Aleksandrovskii Yu.A. Sotsial'no-stressovye rasstroistva. Russkii med. zhurn. 1996. Vol. 3. No. P. 689-694. (In Russ.).
  2. Asylbekova L.U., Tapalova O.B. K voprosu ob adaptatsii voennosluzhashchikh s razlichnym tipom adaptivnoi plastichnosti mozga k operativno-sluzhebnoi deyatel'nosti. V sb.: «Psikhologiya v Rossii i za rubezhom: materialy mezhdunar. nauch. konf. Sankt-Peterburg, oktyabr' 2011 g. Saint Petersburg: Renome. 2011. P. 66-68. (In Russ.).
  3. Bezdenezhnykh B.N. Psikhofiziologicheskie zakonomernosti vzaimodeistviya funktsional'nykh sistem pri realizatsii deyatel'nosti. Moscow: Diss. dokt. med. nauk. 2004. 292 p. (In Russ.).
  4. Berezin F.B. Psikhicheskaya i psikhofiziologicheskaya adaptatsiya cheloveka. Leningrad: Nauka. 1988. 266 p. (In Russ.).
  5. Isaeva N.A. Torubarov F.S., Zvereva Z.F., Luk'yanova S.N. Bioelektricheskaya aktivnost' golovnogo mozga u rabotnikov Bilibinskoi atomnoi elektrostantsii, imeyushchikh risk razvitiya ishemicheskogo insul'ta. Medical Radiology and Radiation Safety. 2013. Vol. 58 No. 4. P. 48-54. (In Russ.).
  6. Isaeva N.A. Torubarov F.S., Zvereva Z.F. Otsenka riska sosudistykh zabolevanii golovnogo mozga u rabotnikov Bilibinskoi AES. Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 2. P. 39-45. (In Russ.).
  7. Torubarov F.S., Zvereva Z.F., Isaeva N.A. et al. Osobennosti bioelektricheskoi aktivnosti golovnogo mozga u rabotnikov AES s razlichnym urovnem psikhofiziologicheskoi adaptatsii. Materialy XII Vserossiiskogo kongressa «Professiya i zdorov'e» V Vserossiiskogo s"ezda vrachei-profpatologov», 27-30 noyabrya 2013 g., Moscow. P. 458-459. (In Russ.).
  8. Bazanova O.M. Sovremennaya interpretatsiya α-aktivnosti EEG. Uspekhi fiziol. nauk. 2009. No. 3. P. 32-53. (In Russ.).
  9. Dmitrieva N.V. Elektrofiziologicheskie mekhanizmy razvitiya adaptatsionnykh protsessov. Fiziologiya cheloveka. 2004. Vol. 30. No. 3. P. 35-44. (In Russ.).
  10. Korobeinikova E.P. Izmeneniya al'fa-ritma cheloveka pri obshchikh nespetsificheskikh adaptatsionnykh reaktsiyakh, vyzvannykh PeMP. V sb.: «Primenenie lazerov i magnitov v biologii i meditsine». Rostov-on-Don. 1983. P. 64-67. (In Russ.).
  11. Poleshchuk T.S. Profil' funktsional'noi asimmetrii mozga i adaptatsiya studentov k uchebnomu protsessu. Avtoref. diss. kand. med. nauk. Vladivostok. 2011. 41 p. (In Russ.).
  12. Bobrov A.F., Zarudnyi D.I., Zubin S.V., Shcheblanov V.Yu. Sistema podderzhki prinyatiya resheniya pri otsenke professional'noi nadezhnosti personala ob"ektov ispol'zovaniya atomnoi energii. Meditsina katastrof. No. 6. 2006. P. 6-11. (In Russ.).
  13. Bobrov A.F. Informatsionnyi tekhnologii v meditsine truda. Meditsina truda i promyshlennaya ekologiya. 2013. No. 9. P. 40-47. (In Russ.).
  14. Kotenko K.V., Bushmanov A.Yu., Shcheblanov V.Yu., Bobrov A.F. Rukovodstvo po otsenke i interpretatsii rezul'tatov monitoringa psikhofiziologicheskogo sostoyaniya rabotnikov organizatsii, ekspluatiruyushchikh osobo radiatsionno i yadernoopasnye proizvodstva i ob"ekty v oblasti ispol'zovaniya atomnoi energii. Metodicheskie rekomendatsii. 2014. (In Russ.).
  15. Baevskii R.M., Berseneva A.P. Otsenka adaptatsionnykh vozmozhnostei organizma i risk razvitiya zabolevanii. Moscow: Meditsina. 1997. 236 p. (In Russ.).
  16. Zhirmunskaya E.A. Klinicheskaya elektroentsefalografiya. Moscow: Meibi. 1991. 77 p. (In Russ.).
  17. Zhirmunskaya E.A. Elektroentsefalograficheskaya kharakteristika distsirkulyatornoi entsefalopatii. Nevropatologiya i psikhiatriya im. S.S. Korsakova. 1991. Vol. 91. No. 1 P. 35-41. (In Russ.).
  18. Zenkov L.R. Klinicheskaya elektroentsefalografiya. Publ. Taganrogskogo Un-ta. 1996. 358 p. (In Russ.).
  19. Zenkov L.R., Ronkin M.A. Funktsional'naya diagnostika nervnykh boleznei. 2-e izdanie. Moscow: Meditsina. 2004. P. 7-146. (In Russ.).
  20. Luk'yanova S.N. Bioelektricheskaya aktivnost' kory i nekotorykh podkorkovykh obrazovanii pri eksperimental'nom nevroze. ZhVND. 1976. Vol. 26. No. 3. P. 539-547. (In Russ.).
  21. Boldyreva G.N. Elektricheskaya aktivnost' mozga pri porazhenii dientsefal'nykh i limbicheskikh struktur. Moscow: Nauka. 2000. 181 p. (In Russ.).
  22. Latash L.P. Gipotalamus. Prisposobitel'naya aktivnost' i elektroentsefalogramma. Moscow: Nauka. 295 p. (In Russ.).
  23. Povorinskii A.G. Strukturnye izmeneniya EEG i nekotorye mekhanizmy vnutritsentral'nykh otnoshenii, skladyvayushchiesya pri porazhenii retikulyarnoi formatsii stvola golovnogo mozga cheloveka. V sb.: «Fiziologiya i patofiziologiya limbikoretikulyarnoi sistemy». Moscow. 1971. P. 75-80. (In Russ.).
  24. Sel'e G. Stress bez distressa. Transl. from engl. Moscow: Progress. 124 p. (In Russ.).

For citation: Isaeva NA, Torubarov FS, Zvereva ZF, Lukyanova SN, Denisova EA. TActivity of the Brain of Employees of the Novovoronezh and Beloyarsk NPPs at Different Levels of Psychophysiological Adaptation to the Conditions of Their Work. Medical Radiology and Radiation Safety. 2016;61(5):5-12. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 6. P. 16-24

RADIATION MEDICINE

Yu.V. Semenova1,2, A.B. Karpov1,3, R.M. Takhauov1,3, D.E. Maximov1,3, M.Yu. Kirillova2, A.G. Zerenkov1, E.V. Efimova4

The Dinamics and Level of Acute Miocardial Infarction Morbidity in People Exposed To Occupational Irradiation

1. Seversk Biophysical Research Center, Seversk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Seversk Clinical Hospital of the Siberian Federal Research and Clinical, Seversk, Russia; 3. Siberian State Medical University, Tomsk, Russia; 4. Cardiology Research Institute, Tomsk, Russia

ABSTRACT

Purpose: To study the levels and dynamics of the acute myocardial infarction (AMI) morbidity in people exposed to occupational irradiation taking into account the influence of the non-radiation risk factors for the development of cardiovascular diseases over the period 1998-2013.

Material and methods: The study is the prospective population research which was started in 1998 and has being developed. The research cohort of Siberian Group of Chemical Enterprises (SGCE) personnel includes the total number of the employees started employment from 01.01.1950 to 31.12.1995 (30,112 people: 20,995 men and 9,117 women). By the end of the current follow-up 20,751 people were alive and 9,361 people died. From the total number employees of the cohort 6,334 men and 2,056 women were monitored to external exposure. The AMI was diagnosed in 1,470 employees (1,091 men and 379 women). 630 SGCE employees - AMI patients (529 men and 101 women) had the data of external and/or internal dosimetry.

Results: It was established that the male and female SGCE personnel not exposed to occupational irradiation had higher level of AMI morbidity and higher growth rate of the AMI morbidity standardize coefficients over the period 1998-2013 compared to the SGCE employees exposed to irradiation (having contact to sources of ionizing radiation in a workplace), and higher growth rates of the standardized case rate coefficients an acute myocardial infarction. A slight decrease of the AMI morbidity among the SGCE male personnel in the study period (13.8 %), apparently due to the implementation of state programs of the cardiovascular diseases prevention of complications.

Key words: risk factors, low doses, acute myocardial infarction

REFERENCES

  1. Fajardo L.F., Berthronq M., Anderson R.E. Radiation patholoqy. - Oxford: Oxford University press. Р. 165-180.
  2. Kabasheva N.Ya., Okladnikova N.D., Mamakova O.V. Prichiny letal'nykh iskhodov i morfologicheskaya kharakteristika serdechno-sosudistoi sistemy v otdalennyi period posle khronicheskogo oblucheniya. Kardiologiya. 2001. No. 11. P. 78-81. (In Russ.).
  3. Bolotnikova M., Koshurnikova N., Komleva N., Budushchev, E.B. Mortality from cardiovascular diseases among male workers at the radiochemical plant of the «Mayak» complex. Sci. Total Environ. 1994. Vol. 142. Р. 29-31.
  4. Little M.P., Tawn E.J., Tzoulaki I. et al. Review and meta-analysis of epidemiological associations between low/moderate doses of ionizing radiation and circulatory disease risks, and their possible mechanisms. Radiat. Environ. Bioph. 2010. Vol. 49. Р. 139-153.
  5. Little M.P., Kleinerman R.A., Stovall M. et al. Analysis of dose response for circulatory disease after radiotherapy for benign disease. Int. J. Radiat. Oncol. 2012. Vol. 84. No. 5. P. 1101-1109.
  6. Little M.P., Azizova T.V., Bazyka D. et al. Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks. Environ. Health. Persp. 2012. Vol. 120. No. 11. P. 1503-1511.
  7. Kamiya K., Ozasa K., Akiba S. et al. Long-term effects of radiation exposure on health. Lancet. 2015. Vol. 386. No. 9992. P. 469-478.
  8. Laurent O., Metz-Flamant C., Rogel A. et al. Relationship between occupational exposure to ionizing radiation and mortality at the French electricity company, period 1961-2003. Int. Arch. Occ. Env. Hea. 2010. Vol. 83. No. 8. Р. 935-944.
  9. Darby S.C., Cutter D.J., Boerma M. et al. Radiationrelated heart disease: current knowledge and future prospects. Int. J. Radiat. Oncol. 2010. Vol. 76. No. 3. Р. 656-665.
  10. Baker J.E., Moulder J.E., Hopewell J.W. Radiation as a risk factor for cardiovascular disease. Antioxid Redox Sign. 2011. Vol. 15. No. 7. Р. 1945-1956.
  11. Azizova T.V., Muirhead C.R., Druzhinina M.B. et al. Cardiovascular Diseases in the Cohort of Workers First Employed at Mayak PA in 1948-1958. Radiat Res, 2010, Vol. 174. No. 2, P. 155-168.
  12. Kreuzer M., Dufey F., Sogl M. et al. External gamma radiation and mortality from cardiovascular diseases in the German WISMUT uranium miners cohort study, 1946-2008. Radiat. Environ. Biophys. 2013. Vol. 52. No. 1. P. 37-46.
  13. Zablotska L.B., Little M.P., Cornett R.J. Potential increased risk of ischemic heart disease mortality with significant dose fractionation in the Canadian Fluoroscopy Cohort Study. Amer. J. Epidemiol. 2014. Vol. 179. No. 1. P. 120-131.
  14. Drubay D., Caër-Lorho S., Laroche P. et al. Mortality from circulatory system diseases among French Uranium Miners: A nested case-control study. Radiat. Res. 2015. Vol. 183. No. 5. P. 550-562.
  15. Karpov A.B., Semenova Yu.V., Takhauov R.M. et al. The risk of acute myocardial infarction and arterial hypertension in a cohort of male employees of Siberian Group of Chemical Enterprises exposed to long-term irradiation. Health Phys. 2012. Vol. 103. No. 1. P. 15-23.

For citation: Semenova YuV, Karpov AB, Takhauov RM, Maximov DE, Kirillova MYu, Zerenkov AG, EfimovaI EV. The Dinamics and Level of Acute Miocardial Infarction Morbidity in People Exposed To Occupational Irradiation. Medical Radiology and Radiation Safety. 2016;61(6):16-24. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 6. P. 11-15

RADIATION SAFETY

N.K. Shandala1, D.V. Isaev1, A.V. Titov1, V.А. Seregin1, S.М. Kiselev1, М.P. Semenova1, А.А. Filonova1, N.Ya. Novikova1, I.G. Lazareva2, N.G. Biryukova2

Radiation Survey Around the «Zvezda» Plant in the Russian Far East

1. A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Center for Hygiene and Epidemiology № 98 FMBA of Russia, Bolshoy Kamen, Primorsky Region, Russia

ABSTRACT

Purpose: To obtain data on the radiation situation around JSC Zvezda Far Eastern Yard after completion of the main stage of nuclear submarine Decommissioning & Dismantlement (D&D) operations.

Material and methods: For the purpose of the radiation survey around JSC Zvezda Far Eastern Yard we used methods of foot gamma shooting, gamma-spectrometric measurements of radionuclides in the environmental media using stationary gamma spectrometer, radiochemical separation of radionuclides, followed by radiometric measurement of the radionuclide activity.

Results: The survey was carried out in 2011-2012. The received results include: gamma dose rates in the area of Bolshoy Kamen city and in its vicinity; specific activities of radionuclides in soil and foodstuffs; and radionuclide concentrations in the marine environmental media (such as seaweeds, bottom sediments, marine fish) of the coastal water area of BolshoyKamen, Sukhodol and Andreyeva Bays.

Conclusions: Significant impact of nuclear submarines’ D&D operations on the radiation situation within the territory in the area of JSC Zvezda Far Eastern Yard is not revealed.

Key words:nuclear submarines, recycle, radiation examination, gamma radiation, the specific activity

REFERENCES

  1. Metodicheskie ukazaniya. Ustanovlenie kategorii potentsial'noi opasnosti radiatsionnogo ob"ekta. MU 2.6.1.2005-05. Moscow. 2005. 5 p. (In Russ.).
  2. Metodicheskie rekomendatsii po sanitarnomu kontrolyu za soderzhaniem radioaktivnykh veshchestv v ob"ektakh vneshnei sredy. In: Mareya A.N. & Zykovoi A.S. (eds.). Moscow: Minzdrav SSSR. 1980. 335 p. (In Russ.).
  3. MUK 4.3.2503-09 Strontsii-90. Opredelenie udel'noi aktivnosti v pishchevykh produktakh. 1.31.2011.10330. Moscow, 2009. (In Russ.).
  4. MUK 4.3. 2504-09 Tsezii-137. Opredelenie udel'noi aktivnosti v pishchevykh produktakh. FR. 1.38.2003.00948. Moscow, 2009. (In Russ.).
  5. MUK 2.6.1.033-2003 Strontsii-90. Opredelenie kontsentratsii v pochve ekstraktsiei monoizook-tilovym efirom metilfosfonovoi kisloty ittriya-90. 1.31.2011.10329. Moscow, 2003. (In Russ.).
  6. Doklad ob ekologicheskoi situatsii v Primorskom krae. Administratsiya Primorskogo kraya. Vladivostok. 73 p. (In Russ.).
  7. Normy radiatsionnoi bezopasnosti (NRB-99/2009): Sanitarnye pravila i normativy SanPiN 2.6.1.2523-09. Moscow: Federal'nyi tsentr gigieny i epidemiologii Rospotrebnadzora. 2009. 100 p. (In Russ.).
  8. Sanitarno-epidemiologicheskie pravila i normativy. Gigienicheskie trebovaniya bezopasnosti i pishchevoi tsennosti pishchevykh produktov. SanPiN 2.3.2.1078-01. Moscow: FGUP InterSEN. 2002. (In Russ.).
  9. Tekhnogennye radionuklidy v moryakh, omyvayushchikh Rossiyu. Moscow: IzdAT. 2005. 624 p.
  10. Osnovnye sanitarnye pravila obespecheniya radiatsionnoi bezopasnosti (OSPORB-99/2010). Sanitarnye pravila i normativy SP 2.6.1.2612-Federal'nyi tsentr gigieny i epidemiologii Rospotrebnadzora. Moscow. 2010. 83 p. (In Russ.).

For citation: Shandala NK, Isaev DV, Titov AV, Seregin VA, Kiselev SM, Semenova MP, Filonova AA, Novikova NYa, Lazareva IG, Biryukova NG. Radiation Survey around the «Zvezda» Plant in the Russian Far East. Medical Radiology and Radiation Safety. 2016;61(6):11-5. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 6. P. 5-10

RADIATION BIOLOGY

l.H. Poghosyan1, Z.S. Mkrtchyan1, M.G. Gazaryants1, M.G. Malakyan1, l.E. Abramyan2, G.O. Meliksetyan1, J.I. Akopyan1

Influence of Electromagnetic Radiation with Frequency of 900 and 1800 MHz on the Activity of Purine Nucleoside Phosphorylase and Alkaline Phosphatase in Some Organs of the Rats

1. Institute of Molecular Biology of NAS RA, Erevan, Armenia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Erevan State University. Faculty of Radiophysics, Erevan, Armenia

Abstract

Purpose: The sharp increase in the use of mobile phones has put on the agenda the question of the need to study the adverse effects of electromagnetic radiation emitted by mobile phones on the human health. The objective of the paper is to study the effect of low-intensity electromagnetic radiation at frequencies 900 and 1800 MHz (the standards of cellular communication) at levels of purine nucleoside phosphorylase (PNP) activity in the blood serum, liver, and brain of rats, and the alkaline phosphatase (AP) in the serum of rats using two schemes of radiation scheme: single and fractionated (fractional) at different terms of postradiation (the 1st, the 5th, the 10th and the 20th day).

Material and methods: The objects of the study were two enzymes - PNP and AP. PNP is one of the enzymes that characterizes the immune status of the organism. Inhibition of this enzyme leads to the disruption of homeostasis of nucleosides that causes T cell immunodeficiency. AP is involved in the metabolism of phosphoric acid, contributes to phosphorous transport in the body. The materials of the study were white mongrel male rats radiated by a single (two hours continuously) and fractional (for half an hour for four consecutive days) schemes of electromagnetic radiation with frequencies of 900 and 1800 MHz. SPSS package was used for statistical data processing (Statistical Package for Social Science).

Results: Electromagnetic radiation causes oscillatory character of the change in activity of the AP and almost completely inhibits the activity of PNP in the serum. Toxic effect did not affect the activity of the brain and hepatic purine nucleoside phosphorylase. The enzyme in these organs proved resistant properties to this mode of radiation.

Conclusion: It is shown that the electromagnetic radiation with frequencies of 900 and 1800 MHz inhibits PNP in the serum and in the liver and brain enzyme exhibits resistant properties to the action of the radiation, which is apparently due to the absence of toxic effects in these tissues under the influence of the used irradiation modes. The vibrational change of AP activity in serum testify to a considerable sensitivity of serum AP to the effects of the used type of radiation. In subsequent experiments it will be necessary to increase the duration of exposure. In the following experiments it will be necessary to increase the duration of the irradiation.

Key words: purine nucleoside phosphorylase, alkaline phosphatase, activity, electromagnetic radiation, cellular communications

REFERENCES

  1. Sedov D.P., Makhina V.I., Ivanchenko M.N. Vliyanie elektromagnitnogo izlucheniya, sozdavaemogo mobil'nymi ustroistvami na zdorov'e cheloveka. Byull. med. internet-konferentsii. Vol. 2. No. 11. P. 918-920. (In Russ.).
  2. Bingi V.N. Printsipy elektromagnitnoi biofiziki. Publ.: FIZMATLIT. 2011. 592 p. (In Russ.).
  3. Grigor'ev Yu.G., Grigor'ev O.A., Ivanov A.A. et al. Autoimmunnye protsessy posle prolongirovannogo vozdeistviya elektromagnitnykh polei maloi intensivnosti (rezul'taty eksperimenta). Soobshchenie 1. Mobil'naya svyaz' i izmenenie elektromagnitnoi sredy obitaniya naseleniya. Neobkhodimost' dopolnitel'nogo obosnovaniya sushchestvuyushchikh gigienicheskikh standartov. Radiats. biol. Radioekologiya. 2010. No. 1. P. 5-11. (In Russ.).
  4. Jauchem J.R. A literature review of medical side effects from radiofrequency energy in the human environment: involving cancer, tumors and problems of the central nervous system. J. Microw. Power. Electromagn. Energy. 2003. Vol. 38. No. 2. P. 103-123.
  5. Badzhinyan S.A., Malakyan M.G., Egiazaryan D.E. et al. Vliyanie elektromagnitnogo izlucheniya s chastotoi 900 MGts na nekotorye pokazateli krovi. Radiats. biol. 2013. Vol. 53. No. 1. P. 63-70. (In Russ.).
  6. Pogosyan L.G., Gazaryants M.G., Mkrtchyan Z.S. et al. Ingibitory purinnukleozidfosforilazy i ikh klinicheskoe znachenie. Ukr. biokhim. zhurnal. 2011. Vol. 80. No. 5. P. 95-104. (In Russ.).
  7. El Bediwi Abu Bakr, El-Kott Attal F., Mohamed Saad, et al. Effects of electromagnetic radiation produced by mobile phone on some visceral organs of rat. J. Med. Sci. 2011. Vol. 11. No. 6. P. 256-260.
  8. Dindic B., Sokolovic D., Krstic D. et al. Biochemical and histopathological effects of mobile phone exposure on rat hepatocytes and brain. Acta Medica Medanae. 2010. Vol. 49. No. 1. P. 37-42.
  9. Petrosyan M.S., Nersesova L.C., Gazaryants M.G. i soavt. Deistvie nizkointensivnogo elektromagnitnogo izlucheniya s chastotoi 900 MGts na aktivnosti fermentov, uchastvuyushchikh v energeticheskom obmene mozga krys. Radiats. biol. Radioekologiya. 2015. Vol. 55. No. 6. P. 1-7. (In Russ.).
  10. Grigor'ev Yu.G. Sravnitel'nye otsenki opasnosti ioniziruyushchikh i ne ioniziruyushchikh elektromagnitnykh izluchenii. Radiats. biol. Radioekologiya. 2012. Vol. 52. No. 2. P. 215-218. (In Russ.).
  11. Nersesova L.C., Petrosyan M.S., Gazaryants M.G. et al. Deistvie nizkointensivnogo elektromagnitnogo izlucheniya s chastotoi 900 MGts na fermentnye aktivnosti pecheni i syvorotki krovi krys. Radiats. biol. Radioekologiya. 2014. Vol. 54. No. 5. P. 1-9. (In Russ.).
  12. Bzowska A., Kulikowska E., Shugar D. Purin nucleoside phosphorylase: properties, functions and clinical aspect. Pharmacol. & Therapeut. 2000. Vol. 88. No. 3. P. 349-425.
  13. Tietz N.W. Clinical guide to laboratory. 3d ed. Philadelphia, PA. Saunders Co. 1995. 374 p.
  14. Khorseva N.I., Grigor'ev Yu.G., Gorbunov N.V. Psikhofiziologicheskie pokazateli detei - pol'zovatelei mobil'noi svyaz'yu. Soobshchenie 1. Sovremennoe sostoyanie problem. Radiats. biol. Radioekologiya. 2011. Vol. 51. No. 5. P. 611-616. (In Russ.).

For citation: Poghosyan LH, Mkrtchyan ZS, Gazaryants MG, Malakyan MG, Abramyan LE, Meliksetyan GO, Akopyan JI. Influence of Electromagnetic Radiation with Frequency of 900 and 1800 MHz on the Activity of Purine Nucleoside Phosphorylase and Alkaline Phosphatase in Some Organs of the Rats. Medical Radiology and Radiation Safety. 2016;61(6):5-10. Russian.

PDF (RUS) Full-text article (in Russian)

Contact Information

 

46, Zhivopisnaya st., 123098, Moscow, Russia Phone: +7 (499) 190-95-51. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal location

Attendance

2927111
Today
Yesterday
This week
Last week
This month
Last month
For all time
2128
2221
4349
33458
25407
113593
2927111

Forecast today
2232


Your IP:216.73.216.82