JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 4. P. 52-58
RADIATION EPIDEMIOLOGY
I.A. Martinenko1, M.E. Sokolnikov1, N.A. Koshurnikova1, Yu.G. Mokrov2, D.A. Beregich2
Risk Assessment of Thyroid Cancer Incidence Among Population Due to the Residence Close to Mayak PA
1. Southern Urals Biophysics Institute, Ozersk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Mayak PA, Ozersk, Russia
ABSTRACT
Purpose: Thyroid cancer incidence rates in the population residing as children in areas contaminated by radioactive gas-aerosol emissions during technological development at Mayak PA were assessed in the current epidemiological study.
Material and methods: The study was carried out in a cohort of 31,836 people residing in childhood in Ozersk during 1948-1962. In that period uncontrolled gas-aerosol emissions from chimneys of radiochemical plants took place. There were 60 thyroid cancer cases diagnosed and histologically verified in the study cohort. Standardized incidence rates (SIR) were estimated by the indirect standardization by age and sex with a 95 % confidence interval. Age- and sex-related thyroid cancer incidence rates in Russia and among the urban population of Chelyabinsk were chosen as a standard. Information on radiation exposure levels of thyroid for Ozersk residents of different ages was obtained on the basis of preliminary dose calculations for two scenarios of food consumption from different suppliers. Radiation excess relative risk per unit dose (ERR/Sv) was calculated with the us of a Poisson regression model implemented in Amfit module of the Epicure software.
Results: SIR of thyroid cancer in the cohort was 3.16 among men (1.68-5.06) and 2.07 (1.52-2.65) among women compared to the data of national statistics. Significant difference of thyroid cancer incidence in the cohort compared to the regional statistics was also found: SIR was 2.04 (1.08-3.26) among men and 1.59 (1.17-2.04) among women. ERR/Sv was -0.03 (p > 0.5), i.e. increase of thyroid cancer incidence in the study cohort is not associated with the obtained estimates of equivalent doses to the thyroid.
Conclusion: In the cohort of persons residing as children in Ozersk in the period of uncontrolled gas-aerosol emissions from the chimneys of radiochemical plants in 1948-1962, age- and sex-related thyroid cancer incidence rates and relative risk of thyroid cancer incidence in men and women significantly (2-3 times) exceeded those in the national and regional statistics. The correlation between dose and effect was not observed. It could be associated with using group doses due to lack of individual doses.
Key words: thyroid cancer incidence, Mayak PA, radiation risk, standardized incidence ratio
REFERENCES
- Il'in L.A. et al. Radioaktivnyi iod v probleme radiatsionnoi bezopasnosti. Moscow: Atomizdat. 1972. 272 p. (In Russ.).
- Akleev A.V., Krestinina L.Yu., Preston D. et al. Radiatsionnyi risk zlokachestvennykh novoobrazovanii u zhitelei pribrezhnykh sel reki Techi. Medical Radiology and Radiation Safety. 2008. Vol. 53. No. 4. P. 13-37. (In Russ.).
- Glagolenko Yu.V., Drozhko E.G., Mokrov Yu.G. et al. Metodika rekonstruktsii radionuklidnogo sostava i aktivnosti oskolkov deleniya, nakaplivayushchikhsya v obluchennom urane na moment ego radiokhimicheskoi pererabotki na zavode «B» PO «Mayak» v nachale 1950-kh gg.. Voprosy radiats. bezopasnosti. Spets. vyp. 2008. P. 35-51. (In Russ.).
- Glagolenko Yu.V., Drozhko E.G., Mokrov Yu.G. et al. Rekonstruktsiya vybrosov v atmosferu ioda-131 iz trub radiokhimicheskogo proizvodstva PO «Mayak» za period s 1948 po 1967 gg.. Voprosy radiats. bezopasnosti. Spets. vyp. 2008. P. 52-61. (In Russ.).
- Il'in L.A., Aksel' E.M., Drozhko E.G. et al. Zabolevaemost' rakom shchitovidnoi zhelezy sredi zhitelei g. Ozerska (epidemiologicheskoe issledovanie). Medical Radiology and Radiation Safety. 2003. Vol. 48. No. 1. P. 57-64. (In Russ.).
- Koshurnikova N.A., Kabirova N.R., Bolotnikova M.G. et al. Kharakteristika registra lits, prozhivavshikh v detskom vozraste vblizi proizvodstvennogo ob"edineniya «Mayak». Medical Radiology and Radiation Safety. 2003. Vol. 48. No. 1. P. 27-34. (In Russ.).
- Mokrov Yu.G., Martyushov V.Z., Stukalov P.M. et al. Osobennosti struktury pitaniya naseleniya g. Ozerska za period s 1948 po 1966 gg., znachimye dlya otsenki peroral'noi sostavlyayushchei doz vnutrennego oblucheniya. Voprosy radiats. bezopasnosti. Spets. vypusk. 2008. P. 62-75. (In Russ.).
- Fomin E.P., Okatenko P.V., Koshurnikova N.A. Opyt retrospektivnogo sozdaniya kantser-registra dlya naseleniya g. Ozerska i analiz pokazatelei zabolevaemosti zlokachestvennymi novoobrazovaniyami na ego osnove s 1948 po 2005 gg.. Voprosy radiats. bezopasnosti. 2007. No. 4. P. 54-62. (In Russ.).
- Davydov M.I., Aksel' E.M. Statistika zlokachestvennykh novoobrazovanii v Rossii i stranakh SNG v 2005 g.. Vestnik RONTs im. N.N. Blokhina RAMN. 2007. Vol. 18. No. 2. 156 p. (In Russ.).
- Glagolenko Yu.V., Drozhko E.G., Mokrov Yu.G. et al. Metodika i rezul'taty rekonstruktsii vybrosov inertnykh radioaktivnykh gazov iz trub grafitovykh reaktorov PO «Mayak» za ves' period ikh ekspluatatsii. Voprosy radiats. bezopasnosti. Spets. vypusk. 2008. P. 6-21. (In Russ.).
- Sbyder S.F., Farris W.T., Napier B.A., Ikenberry T.A. et al. Parameters used in the environmental pathway and radiological dose modules (DESCARTES, CIDER and CRD Codes) of the Hanford Environmental Dose Reconstruction Integrated Codes (HEDRIC). In: PNWD-2023. Rev. 1. UC-000. Battelle. Pacific Northwest Laboratories. Richland. Washington. (In Russ.).
- Preston D.L., Lubin J.H., Pierce D.A. EPICURE user’s Guide. Seattle: Hirosoft International Corp. 1993. 330 p. (In Russ.).
- Masharova E.I., Azizova T.V., Chutchikova T.A. et al. Rasprostranennost' patologii shchitovidnoi zhelezy v kogorte zhitelei g. Ozerska, podvergshikhsya v detskom vozraste tekhnogennomu oblucheniyu. Klinich. i eksperim. tireoidologiya. 2011. Vol. 7. No. 4. P. 56-62. (In Russ.).
- Koshurnikova N.A., Martinenko I.A., Kaigorodova L.Ya. et al. Zabolevaemost' rakom shchitovidnoi zhelezy pri prozhivanii v detskom vozraste vblizi atomnogo predpriyatiya. V sb.: «Istochniki i effekty oblucheniya rabotnikov PO «Mayak» i naseleniya, prozhivayushchego v zone vliyaniya pred-priyatiya». Chast' IV. Kiseleva M.F., Romanova S.A. (Eds.). Chelyabinsk: Chelyabinskii Dom pechati. 2012. P. 187-204. (In Russ.).
- Martinenko I.A., Sokol'nikov M.E. Otnositel'nyi risk zabolevaniya rakom shchitovidnoi zhelezy u zhitelei dvukh raionov ZATO g. Ozersk. Voprosy radiats. bezopasnosti. 2012. No. 2. P. 66-72. (In Russ.).
For citation: Martinenk IA, Sokolnikov ME, Koshurnikova NA, Mokrov YuG, Beregich DA. Risk Assessment of Thyroid Cancer Incidence among Population Due to the Residence Close to Mayak PA. Medical Radiology and Radiation Safety. 2016;61(4):52-8. Russian.
Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 4. P. 48-51
DIAGNOSTIC RADIOLODGY
S.E. Okhrimenko1, I.P. Korenkov2, N.A. Akopova1, S.A. Ryzhkin3, S.I. Ivanov1
Patient Dose Optimization During X-Ray Investigation
1. Russian Medical Academy of Postgraduate Education, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. , 2. A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, 3. Kazan Federal University, Kazan, Russia
ABSTRACT
Purpose: To estimate the technical condition of the ӭray machine park in Moscow, according to the establishment of patient exposure levels from the technical condition.
Material and methods: Radiation monitoring of physical and technical parameters of X-ray machines, patient dose assessment due to X-ray studies.
Results: The evaluation of the technical condition of x-ray park of Moscow, the assessment of radiation exposure of patients for 1998-2013 is given. The dependence of radiation doses of patients from the technical condition of the X-ray diagnostic apparatus was estimated. It is established that the patient radiation dose should be evaluated in each case, and the use of averaged (tabular) values leads to significant distortions during the assessing radiation exposure. One of the main aspects of ensuring radiation safety of patients is the implementation of the principle of optimization: the maximum possible decrease in exposure to patients while maintaining appropriate quality diagnostic information. The crucial thing in the implementation of this task is played by the staff understanding the need to reduce the radiation doses of patients, the influence of the technical condition of the equipment at the radiation exposure and the implementation presented in the paper approaches into everyday practice.
Summary: Analysis of the results shows that the dose of irradiation of patients from 1998 to 2013 decreased by more than 2.5 times. Reduced radiation exposure associated with the decommissioning of the X-ray machines that do not meet the requirements of the applicable regulations, the introduction of digital technology, the introduction of patient dose monitoring during radiological procedures.
Keywords: X-ray radiation, patients, effective radiation doses, radiationhygienic passport, fluoroscopy, radiography, CT scan
REFERENCES
- NKDAR OON, 2012. Istochniki i effekty ioniziruyushchego izlucheniya. Doklad Nauchnogo komiteta OON po deistviyu atomnoi radiatsii 2000 g. General'noi Assamblee s nauchnymi prilozheniyami. Transl. from engl. New York. 2012. 756 p. (In Russ.).
- Stavitskii R.V., Blinov N.N., Rabkin I.Kh., Lebedev L.A. Radiatsionnaya zashchita v meditsinskoi rentgenologii. Moscow: Kabur. 1994. 272 p. (In Russ.).
- Radiatsionno-gigienicheskii pasport territorii g. Moskvy za 1998. Moscow. 1999. 6 p. (In Russ.).
- Gigienicheskie trebovaniya k ustroistvu i ekspluatatsii rentgenovskikh kabinetov, apparatov i provedeniyu rentgenologicheskikh issledovanii. SanPiN 2.6.1.802-99. (In Russ.).
- Gigienicheskie trebovaniya k ustroistvu i ekspluatatsii rentgenovskikh kabinetov, apparatov i provedeniyu rentgenologicheskikh issledovanii. SanPiN 2.6.1 1192-03. (In Russ.).
- Voronin K.V., Okhrimenko S.E., Nikitina M.N. Izmerenie proizvedeniya dozy na ploshchad' kak metod kontrolya parametrov rentgenovskogo apparata i optimizatsii doz oblucheniya patsientov. ANRI. 2000. No. 4. P. 65-69. (In Russ.).
- Okhrimenko S.E., Voronin K.V., Ivanov S.I., Akopova N.A. Obespechenie radiatsionnoi bezopasnosti v rentgenodiagnostike s primeneniem novykh tekhnologii. Zdravookhranenie i med. tekhnika. 2004. No. 4. P. 36-37. (In Russ.).
- Okhrimenko S.E., Ivanov S.I., Lazarenko V.N. et al. Ispol'zovanie ekspluatatsionnykh parametrov rentgenovskikh apparatov v kachestve kriteriev dlya prinyatiya resheniya o prodlenii sroka ikh ekspluatatsii. Vestnik Saint Petersburg. gos. med. akademii im. I.I. Sechenova. 2002. No. 3. P. 56-59. (In Russ.).
- Okhrimenko S.E., Voronin K.V., Ivanov S.I. Effektivnye dozy patsientov, poluchennye na osnove izmerenii DRK-1 v LPU g. Moscow: ANRI. 2003. No. 1. P. 39-43. (In Russ.).
- Romanovich I. K. Aktual'nye zadachi radiatsionnoi gigieny v svete itogov FTsP YaRB. Rossiiskaya nauchnaya konferentsiya «Radiatsionnaya zashchita i radiatsionnaya bezopasnost' v yadernykh tekhnologiyakh». Moscow. 2015. P. 30-38. (In Russ.).
For citation: Okhrimenko SE, Korenkov IP, Akopova NA, Ryzhkin SA, Ivanov SI. Patient Dose Optimization during X-Ray Investigation. Medical Radiology and Radiation Safety. 2016;61(4):48-51. Russian.
Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 4. P. 35-42
RADIATION SAFETY
V.Yu. Nugis, A.Yu. Bushmanov, H.E. Zapadinskaya, M.G. Kozlova, O.A. Tyhonova
Cytogenetic Studies 28-29 Years After the Accident at the Chernobyl NPP
A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Cytogenetic examination of liquidators who worked in different years and residents of different contaminated areas nearly 30 years after the accident at the Chernobyl nuclear power plant.
Material and methods: The cytogenetic studies were carried out with the use of peripheral blood lymphocyte cultures. The majority of individuals were examined with the help of FISH- and classical methods of staining chromosomes in parallel.
Results: In general the frequencies of FISH-detected translocations were above background levels in 15 (out of 58 people): 12 out of 41 liquidators and 3 out of 17 residents of contaminated territories. The single highly aberrant cells contained mostly unstable chromosome aberrations were detected by FISH-analysis in 9 examined individuals. The presence or absence of such cells was not associated with the availability of an estimated dose cytogenetically. The analysis of the data obtained the classical method showed that the overall frequency of chromosome rearrangements and the frequency of chromosome aberrations - indicators of radiation exposure - did not exceed the background values of the examined persons individually.
Conclusion: The obtained cytogenetic data indicate the possibility of cytogenetic dose evaluation in almost 30 years after the radiation accident with the help of FISH-method. The detection of single highly aberrant cells in peripheral blood lymphocyte cultures is characteristic for this contingent that apparently related to the action of alpha-emitting radionuclides.
Key words: chromosome aberrations, peripheral blood, lymphocytes culture, accidental irradiation, the accident at the Chernobyl NPP
REFERENCES
- Pyatkin E.K., Nugis V.Yu., Chirkov A.A. Otsenka pogloshchennoi dozy po rezul'tatam tsitogeneticheskikh issledovanii kul'tur limfotsitov u postradavshikh pri avarii na Chernobyl'skoi AES. Med. radiol. 1989. Vol. 34. No. 6. P. 52-57. (In Russ.).
- Bochkov N.P., Katosova L.D., Sapacheva V.A. et al. Tsitogeneticheskii analiz limfotsitov perifericheskoi krovi u prozhivayushchikh v zagryaznennykh radionuklidami raionakh Kaluzhskoi oblasti. Med. radiol. 1991. Vol. 36, 1. P. 50-52. (In Russ.).
- Vorobtsova I.E., Kolyubaeva S.N., Vorob'eva M.V. et al. Tsitogeneticheskaya kharakteristika detei, postradavshikh v rezul'tate avarii na Chernobyl'skoi AES. Med. radiol. 1993. Vol. 38. No. 10. P. 25-28. (In Russ.).
- Vorobtsova I.E., Mikhel'son V.M., Vorob'eva M.V. et al. Rezul'taty tsitogeneticheskogo obsledovaniya likvidatorov posledstvii avarii na ChAES, provedennogo v raznye gody. Radiats. biologiya. 1994. Vol. 34. No. 6. P. 798-803. (In Russ.).
- Domracheva E.V., Klevezal' G.A., Nechai V.V. et al. Individual'nye dozy oblucheniya, opredelennye dvumya metodami biologicheskoi dozimetrii u zhitelei Chernobyl'skogo regiona i uchastnikov likvidatsii avarii. Gematol. i transfuziol. Vol. 36. No. 12. P. 18-20. (In Russ.).
- Zainullin V.G., Borodkin P.A., Chernyak S.I. et al. Rezul'taty tsitogeneticheskogo obsledovaniya lits, prinimavshikh uchastie v likvidatsii avarii na Chernobyl'skoi AES. Radiobiologiya. Vol. 32. No. 5. P. 668-672. (In Russ.).
- Pilinskaya M.A., Shemetun A.M., Dybskii S.S. et al. Tsitogeneticheskii effekt v limfotsitakh perifericheskoi krovi kak indikator deistviya na cheloveka faktorov Chernobyl'skoi avarii. Radiobiologiya. 1992. Vol. 32. No. 6. P. 632-639. (In Russ.).
- Khandogina E.K., Ageikin V.A., Zvereva S.V. et al. Tsitogeneticheskoe obsledovanie razlichnykh grupp detei, prozhivayushchikh v raionakh Bryanskoi oblasti, zagryaznennykh v rezul'tate Chernobyl'skoi avarii. Radiats. biologiya. 1995. Vol. 35. No. 5. P. 618-625. (In Russ.).
- Khvostunov I.K., Sevan'kaev A.V., Mikhailova G.F. et al. Rol' tsitogeneticheskogo obsledovaniya dlya otsenki posledstvii nekontroliruemogo vozdeistviya radiatsii na cheloveka. V sb.: «Meditsinskie radiologicheskie posledstviya Chernobylya: prognoz i fakticheskie dannye spustya 30 let». V.K. Ivanova (ed.), A.D. Kaprina. Moscow: GEOS. 2015. P. 93-119. (In Russ.).
- Cytogenetic Dosimetry: Applications in Preparedness for and Response to Radiation Emergencies. Vienna: IAEA. 2011. 245 p.
- Vorobtsova I.E., Bogomazova A.N. Stabil'nye khromosomnye aberratsii v limfotsitakh perifericheskoi krovi lits, postradavshikh v rezul'tate avarii na ChAES. Radiats. biologiya. Radioekologiya. 1995. Vol. 35. No. 5. P. 636-640. (In Russ.).
- Sevan'kaev A.V., Mikhailova G.F., Potetnya O.I. et al. Rezul'taty dinamicheskogo tsitogeneticheskogo nablyudeniya za det'mi i podrostkami, prozhivayushchimi na radioaktivno-zagryaznennykh territoriyakh posle Chernobyl'skoi avarii. Radiats. biologiya. 2005. Vol. 45. No. 1. P. 5-15. (In Russ.).
- Snigireva G.P., Shevchenko V.A., Novitskaya N.N. Ispol'zovanie FISH metoda dlya rekonstruktsii pogloshchennykh doz, poluchennykh uchastnikami likvidatsii avarii na Chernobyl'skoi AES. Radiats. biologiya. Radioekologiya. 1995. Vol. 35. No. 5. P. 654-661. (In Russ.).
- Shevchenko V.A., Snigireva G.P. Znachimost' tsitogeneticheskogo obsledovaniya dlya otsenki posledstvii Chernobyl'skoi katastrofy. Radiats. biologiya. Radioekologiya. 2006. Vol. 46. No. 2. P. 133-139. (In Russ.).
- Maznyk N.A., Vinnikov V.A. Retrospective cytogenetic biodosimetry using fluorescence in situ hybridization (FISH) technique in persons exposed to radiation due to the Chornobyl accident. Ukraïns'kii radiologichnii zhurnal. 2005. Vol. 13. No. 1. P. 66-72.
- Nugis V.Yu., Kozlova M.G. Tsitogeneticheskie issledovaniya v dvukh situatsiyakh obnaruzheniya nekontroliruemykh istochnikov ioniziruyushchego izlucheniya. Medical Radiology and Radiation Safety. 2015. Vol. 60. No. 2. P. 37-46. (In Russ.).
- Lucas J.N., Awa A., Straume T. et al. Rapid translocation frequency analysis in human decades after exposure to ionizing radiation. Int. J. Radiat. Biol. 1992. Vol. 62. No. 1. P. 53-63.
- Mendelsohn M.L., Mayall B.H., Bogart E. et al. DNA content and DNA-based centromeric index of 24 human chromosomes. Science. 1973. Vol. 179. No. 78. P. 1126-1129.
- Snigireva G.P., Bogomazova A.N., Novitskaya N.N. et al. Biologicheskaya indikatsiya radiatsionnogo vozdeistviya na organizm cheloveka s ispol'zovaniem tsitogeneticheskikh metodov. Meditsinskaya tekhnologiya No.FS-2007/015-U. Moscow: 2007. 29 p. (In Russ.).
- Vorobtsova I.E., Semenov A.V. Vozrastnaya dinamika chastoty spontannykh i indutsirovannykh in vitro khromosomnykh aberratsii v limfotsitakh krovi cheloveka pri estestvennom i luchevom starenii. Radiats. biologiya. 2010. Vol. 50. No. 3. P. 253-258. (In Russ.).
- Sigurdson A.J., Ha M., Hauptmann M. et al. International study of factors affecting human chromosome translocations. Mutat. Res. 2008. Vol. 652. No. 2. P. 112-121.
- Whitehouse C.A., Edwards A.A., Tawn E.J. et al. Translocation yields in peripheral blood lymphocytes from control populations. Int. J. Radiat. Biol. 2005. Vol. 81. No. 2. P. 139-145.
- Bakaeva O.A. Neobkhodimost' ispol'zovaniya popravki Ietsa v kriterii χ2 proverki nezavisimosti kachestvennykh peremennykh. Nauchnye issledovaniya i ikh prakticheskoe primenenie. Sovremennoe sostoyanie i puti razvitiya 2012: Sb. nauch. trudov SWorld Mezhdunarodnoi nauchno-prakticheskoi konferentsii. Odessa: Publ. KUPRIENKO. 2012. Vol. 2. Vyp. 3. P. 82-83. (In Russ.).
- Savage J.K. Classification and relationships of induced chromosomal structural changes. J. Medical Genetic. 1976. Vol. 13. No. 2. P. 103-122.
- Salassidis K., Georgiadou-Schumacher V., Braselmann H. et al. Chromosome painting in highly irradiated Chernobyl victims: a follow-up study to evaluate the stability of symmetrical translocations and the influence of clonal aberrations for retrospective dose estimation. Int. J. Radiat. Biol. 1995. Vol. 68. No. 3. P. 257-262.
- Kudryashov Yu.B. Radiatsionnaya biofizika (ioniziruyushchie izlucheniya). Pod red. V.K. Mazurika, M.F. Lomanova. Moscow: FIZMATLIT. 448 p.
- Edwards A.A., Lindholm C., Darroudi F. et al. Review of translocations detected by FISH for retrospective biological dosimetry application. Radiat. Protect. Dosim. 2005. Vol. 113. No. 4. P. 396-402.
- Sevan'kaev A.V., Khvostunov I.K., Snigireva G.P. et al. Sravnitel'nyi analiz rezul'tatov tsitogeneticheskikh obsledovanii kontrol'nykh grupp lits v razlichnykh otechestvennykh laboratoriyakh. Radiats. biologiya. 2013. Vol. 53. No. 1. P. 5-24. (In Russ.).
For citation: Nugis VYu, Bushmanov AYu, Zapadinskaya HE, Kozlova MG, Tyhonova OA. Cytogenetic Studies 28-29 Years after the Accident at the Chernobyl NPP. Medical Radiology and Radiation Safety. 2016;61(4):35-42. Russian.
Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 4. P. 43-47
RADIATION SAFETY
Yu.E. Kvacheva
Chernobyl Hot Particles in Lungs of the Participants of the Post-Accident Clean-up Operation and Residents of the Contaminated Regions
A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
ABSTRACT
Purpose: To investigate the morphological specificity of hot particles (HP) retention in the lungs of participants of liquidation of the consequences of the accident at the Chernobyl nuclear power plant and residents of the contaminated territories.
Material and methods: The lungs obtained after the standard manner were examined in total using an elaborated technique based on auto- and histoautoradiography of autopsy materials. Three distinct groups of patients were studied: 12 persons who participated in postaccident clean-up operation (1986-1988) and died 3 years later after the accident; 170 residents of the contaminated regions, who died from casual causes in 1989-1992; and the immediate witnesses of the accident (27) who dying from the acute radiation sickness (ARS).
Results and conclusion: Chernobyl HP were observed in most of patients (24/27; 88 %) died of ARS. These particles presented as mixed alpha-/beta- and pure beta-emitters were seen in pulmonary macrophages (i.e. intracellulary), located predominantly in the bronchioles and alveoli, as well as on the surfaces of alveolar septa (intraluminal localization). Only one of 12 participants of the postaccident clean-up operation had HP in his lungs (1/12; 8.3 %). Morphological specificity of HP retention was similar to the mentioned above (intracellular + intraluminal localization). Three out of 170 (3/170; 1.8 %) residents of the Ukranian and Belorussian regions contaminated by radionuclides, died in 1989-1992 from accidental causes (acute alcohol intoxication, transport injury, suicide, etc.), were shown to have HP. These particles were few in number and, unlike the above presented groups, were visualized in macrophages, located in fibrous tissue along the vessels and bronchi (intramural localization). In addition, all three cases were found to be accompanied by lung pathology indicative of pulmonary self-clearance deficiency.
Key words: Chernobyl NPP disaster, hot particles, human lungs, inhalation retention, autopsy
REFERENCES
- Kut'kov V.A., Murav'ev Yu.V., Aref'eva Z.S., Kamaritskaya O.I. Goryachie chastitsy - vzglyad spustya sem' let posle avarii na Chernobyl'skoi AES. Pul'monologiya. 1993. No. 4. P. 10-19. (In Russ.).
- Ivanov A.E., Mudretsov N.I., Kurshakova N.N. Patologicheskaya anatomiya ostroi luchevoi bolezni. Prakticheskoe rukovodstvo dlya patologoanatomov i sudebno-meditsinskikh ekspertov. Moscow: Publ Voennoe. 1987, 145 p. (In Russ.).
- Charles M.W., Harrison J.D. Hot particle dosimetry and radiobiology - past and present. J. Radiol. Prot. 2007. Vol. 27. No. 3A. P. A97-109.
- Charles M.W., Mill A.J., Darley P.J. Carcinogenic risk of hot-particle exposures. J. Radiol. Prot. 2003. Vol. 23. No. 1. P. 5-28.
- Harrison J. Biokinetic and dosimetric modelling in the estimation of radiation risks from internal emitters. J. Radiol. Prot. 2009. Vol. 29. No. 2A. P. A81-105.
- ICRP PUBLICATION 71 Age-dependent Doses to Members of the Public from Intake of Radionuclides: Part 4 Inhalation Dose Coefficients. Ann. ICRP. 1995.
- Gerardi S. A comparative review of charged particle microbeam facilities. Radiat. Dosimetry. 2006. Vol. 122. No. 1. P. 285-291.
- Malenchenko A.F., Golubenkov A.M. Mediko-biologicheskie aspekty “goryachikh” chastits. Zdravookhranenie Belorussii. 1990. No. 6. P. 41-45. (In Russ.).
- Tyler W.S, Julian M.D. Gross and subgross anatomy of lungs, pleura, connective tissue septa, distal airways, and structural units. In: Comparative Biology of the Normal Lung. Vol. I (Parent RA, ed). Boca Raton, FL: CRC Press, Inc. 1992. P. 37-48.
- Harrison J.D., Stather J.W. The assessment of doses and effects from intakes of radioactive particles. J. Anat. 1996. Vol. 189. No. 4. P. 521-530.
For citation:. Kvacheva YuE. Chernobyl Hot Particles in Lungs of the Participants of the Post-Accident Cleanup Operation and Residents of the Contaminated Regions. Medical Radiology and Radiation Safety. 2016;61(4):43-47. Russian.
Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 4. P. 29-34
RADIATION SAFETY
N.A. Metlyaeva, A.Yu. Bushmanov, V.I. Krasnuk, E.Eu. Zapadinskaya, O.V. Scherbatich, M.V. Bolotnov
Features of Psychophysiological Adaptation of Military Personnel and Personnel of ChNPP, Participated in the Liquidation of the ChNPP Accident in 1986-1987
A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: An evaluation of the efficiency of psychophysiological adaptation of military personnel and personnel of ChNPP, participated in liquidation of consequences of the ChNPP accident in 1986-1987 years.
Material and methods: The study involved 3 groups of participants of the liquidation of the consequences of ChNPP accident, in total - 10 people. The 1st group consisted of military personnel, colonels, 4 people, including 4 military chemical engineers. The 2nd group wasrepresented by two helicopter pilots and one test engineer of aircraft. The 3rd group was the ChNPP personnel, who worked from may 1986, in preparation for commissioning and operation of ChNPP units 1,2,3, in the face of a nuclear-physicist, chief engineer of ChNPP and the shift supervisor of the electrical shop № 1-2 unit of ChNPP. The dose of external gamma-beta radiation in the 1st group was registered in the range of 90-376 mSv, the 2nd - up to 250 mSv, the 3rd - 560-250 mSv.
Results: The rise of the profile parameters of MMPI above 80 T-points were detected in persons of the 1st group on the scale 1Hs-95,38 T-points of the neurotic triad and testified to the strain of mental adaptation, due to concerns about the health, hypochondriac tendencies. The rise of parameters on a scale of 2D-68,80 and 3Hy-72,4; T-points indicated the voltage of psychophysiological adaptation, due to anxiety-demonstrative behavior. The level of the profile of MMPI in persons of the 2nd group indicated the over voltage of mental adaptation, marked by the rise of parameters of higher than 80 T-points as neurotic (1Hs-94,50; 2D-77,60; 3Hy-80,83 T-points), and psychotic triad (6Pa-75,80; 7Pt-68,30; 8Sch-81,26 T-points) with a relative decrease of parameters of the scale 9Ma-61,16 T-points, that indicated the hypochondriac, demonstrative and anxious-depressive tendencies. The profile of MMPI in persons of the 3rd group does not extend beyond the limits of professional and population norms and indicates on the efficient physiological adaptation in this group.
Conclusions: Evaluation of psychophysiological adaptation of military personnel and personnel of ChNPP indicates the over voltage of mental adaptation of military personnel (colonels, helicopter pilots) and effective adaptation of the staff (engineers), combined the basic work in station with participation in liquidation of consequences of the ChNPP accident.
Key words: Chernobyl NPP accident, liquidators, psychophysiological adaptation, motivation, social adaptation, labor success, hypertensive disease, ischemic heart disease
REFERENCES
- Berezin B. Psikhicheskaya i psikhofiziologicheskaya adaptatsiya cheloveka. Leningrad: Nauka. 1988. 267 p. (In Russ.).
- Baevskii R.M., Berseneva A.P., Boiko E.R. et al. Medikoekologicheskie issledovaniya v ramkakh kosmicheskogo eksperimenta «Mars500». Dozonologiya. Problemy zdorovogo obraza zhizni. V sb. «Materialy V mezhdunarodnoi nauchnoi konferentsii». 17-18 dekabrya 2009. Saint Petersburg. 2009. P. 181-183. (In Russ.).
- Bersenev Yu., Chernikova A.G. Dozonologicheskii podkhod k otsenke funktsional'nykh rezervov i ego primenenie k analizu dannykh eksperimenta «Mars500» Dozonologiya. Problemy zdorovogo obraza zhizni. V sb. «Materialy V mezhdunarodnoi nauchnoi konferentsii». 17-18 dekabrya 2009. Saint Petersburg. 2009. P. 184-187. (In Russ.).
- Zakharchenko P., Shcherbuk Yu.A, Grinenko O.A. et al. Formirovanie zdorovogo obraza zhizni naseleniya kak prioritetnaya zadacha pri provedenii pervichnoi profilaktiki zabolevanii. Dozonologiya. Problemy zdorovogo obraza zhizni. V sb. «Materialy V mezhdunarodnoi nauchnoi konferentsii». 17-18 dekabrya 2009. Saint-Petersburg. 2009. P. 269-270. (In Russ.).
- Lartsev M.A., Abramova V.N., Metlyaeva N.A. et al. Metodicheskie ukazaniya po provedeniyu meditsinskikh osmotrov i psikhofiziologicheskikh obsledova nii rabotnikov ob"ektov ispol'zovaniya atomnoi energii. Moscow. 1998. P. 30. (In Russ.).
- French J.R.P., Rogers W., Gobb S. Abgustament as personenviroment. Coping and adaplation. New York. 1974. P. 316-333.
For citation: Metlyaeva NA, Bushmanov AYu, Krasnuk VI, Zapadinskaya EEu, Scherbatich OV, Bolotnov MV. Features of Psychophysiological Adaptation of Military Personnel and Personnel of ChNPP, Participated in the Liquidation of the ChNPP Accident in 1986-1987. Medical Radiology and Radiation Safety. 2016;61(4):29-34. Russian.