SCIENTIFIC AND INFORMATION-ANALYTICAL MAGAZINE

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 2. P. 58-64

RADIATION THERAPY

A.O. Rasulov, D.V. Kuzmichev, V.A. Aliev, Z.Z. Mamedli, S.S. Gordeyev, V.M. Kulushev, A.V. Polinovskiy, I.Sh. Tataev, J.M. Madyarov, A.V. Nazarenko, S.I. Tkachev, V.V. Glebovskaya, N.A. Kozlov

Neoadjuvant Chemoradiotherapy with Consolidation Chemotherapy in Complex Treatment of Locally Advanced Rectal Cancer

N.N. Blokhin Russian Cancer Research Center, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To investigate preliminary results of neoadjuvant chemoradiotherapy followed by neoadjuvant chemotherapy in locallyadvanced rectal cancer patients.

Material and methods: Patients aged >18 with histologycally verified MRI-staged low and medium T3 (CRM+)–4N0–2M0 rectal cancer were included. In group A (21 patients) received a preoperative chemoradiation with GENUS 4 Gy 3 times a week, with regional lymph nodes of 32 Gy to the tumor of the rectum 40 Gy with capecitabine 850 mg/m2 bid per os followed by 2 cycles of XELOX. In group B (20 patients) received the same treatment without consolidating chemotherapy. Toxicity, tumor regression, downstaging and postoperative complications were analyzed.

Results: 40 patients completed treatment according to the protocol. The second XELOX chemotherapy was amended in 1 patient in group A due to cardiac toxicity. Grade 3 toxic events were observed in 2 (9.5 %) patients in group A and in 3 (15 %) patients in group B. No grade 4 toxic events were observed. The median follow-up was 10.8 months. No patients experienced disease progression during this period. Postoperative complications were observed in 17.7 % and in 15 % of the patients respectively. Complete response was observed in 9 (42.9 %) patients in group A. Among those, 4 were referred to watchful waiting and 5 were diagnosed with pathological complete response after surgery. In group B complete response was observed in 3 (15 %) patients.

Conclusions: Combined treatment with consolidating chemotherapy represents a promising strategy for rectal.

Key words: locally advanced rectal cancer, the complex treatment of rectal cancer, chemotherapy is consolidating, medical pathomorphosis

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For citation: Rasulov AO, Kuzmichev DV, Aliev VA, Mamedli ZZ, Gordeyev SS, Kulushev VM, Polinovskiy AV, Tataev ISh, Madyarov JM, Nazarenko AV, Tkachev SI, Glebovskaya VV, Kozlov NA. Neoadjuvant Chemoradiotherapy with Consolidation Chemotherapy in Complex Treatment of Locally Advanced Rectal Cancer. Medical Radiology and Radiation Safety. 2016;61(2):58-64. Russian.

PDF (RUS) Полная версия статьи

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 2. P. 53-57

DIAGNOSTIC RADIOLODGY

V.A. Bessonova1, P.V. Gavrilov2, A.A. Komarskiy1,3, S.R. Korzhenevskiy1, A.S. Chepusov1,3

Reduction of Patient Radiation Dose During Diagnostics with the Digital Pulsed Nanosecond X-ray Systems

1. Institute of Electrophysics, Ural Branch of the RAS, Ekaterinburg, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Saint-Petersburg Research Institute of Phthisiopulmonology, Saint-Petersburg, Russia; 3. Ural Federal University, Ekaterinburg, Russia.

ABSTRACT

Purpose: Investigation of diagnostic and operational capabilities of pulsed nanosecond X-ray complex compared with commercial X-ray systems based on DC-tubes using digital flat panel detectors.

Material and methods: 3 X-ray systems are considered: pulsed X-ray source Jasen-01 with Carestream DRX-1 detector, Definium AMX 700 mobile apparatus with General Electric detector, Evolution HV complex with Canon CXDI-40EC panel detector. The analysis of these systems is based on images quality evaluation and effective dose measurement. DKS-AT 1123 detector and Unifors Xi dosimeter are used for devices radiation parameters control.

Results: Analysis of digital X-ray images shows good results of pulsed system. Snapshots taken by using this device have the same quality as one obtained with Definium AMX 700 system, and its insignificantly is worse than a typical one for Evolution HV. Using pulsed X-ray source with digital detector, we achieve up to 25 times dose decreasing compared with commercial systems with DC-tubes.

Conclusion: Application of pulsed X-ray sources with digital detectors allows to reduce the dose by 25 times comparing with DC-sources. This result is especially important for C-arm device exploitation. Since it operates in real-time mode, application of pulsed X-ray systems with the digital detector significantly decreases patients and medical staff dose and increases the duration of the procedures under X-ray control.

Key words: pulsed X-ray diagnostic system, reduction of radiation exposure, equivalent dose, X-ray, digital detector

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For citation: Bessonova VA, Gavrilov PV, Komarskiy AA, Korzhenevskiy SR, Chepusov AS. Reduction of Patient Radiation Dose During Diagnostics with the Digital Pulsed Nanosecond X-ray Systems. Medical Radiology and Radiation Safety. 2016;61(2):53-7. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 2. C. 39-45

RADIATION MEDICINE

T.A. Varfolomeyeva1, A.A. Akleyev1,2, A.S. Mandrykina1

The Characteristics of Homeostasis in Individuals Chronically Exposed to Radiation in the South Urals at Late Time After Exposure

1. Urals Research Center for Radiation Medicine, Chelyabinsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. , This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. South Ural State Medical University, Chelyabinsk, Russia

ABSTRACT

Purpose: To conduct a study on the characteristics of the quantitatively-cellular, functional and oxidation-reduction homeostasis of the blood system at late time after exposure in residents of the territories contaminated with radionuclides in the South Urals.

Material and methods: The study included a comprehensive analysis of the morpho-functional and oxidant-antioxidant status of the peripheral blood cells in residents of the Techa riverside villages all of whom was exposed to a prolonged non-uniform radiation with a broad dose range (4.7 Gy to the RBM ad maximum, up to 0.4 Gy to the organs of the peripheral immunopoiesis), and of whom the majority of whom had attained old or senile age. The approach used included up-to-date methods of laboratory diagnostics (multipleparameter method for carrying out blood analyses, integrated study of the immune system, assessment of the rates of the oxidative stress). The control group consisted of individuals residing either on uncontaminated territories or on territories with minimum levels of contamination (accumulated dose to the RBM was up to 0.06 Gy, the dose rate reached 0.001 Gy/year).

Results: The obtained data thus allowed us to draw a conclusion regarding the safety of the quantitative-cellular, functional and oxidation-reduction homeostasis of the blood system in persons exposed within the range of accumulative doses to RBM from 0.07 to 4.7 Gy (to the organs of the peripheral immunopoiesis up to 0.4 Gy) in spite of the long-term habitation on contaminated territories and the currently attained old age and senility. The following aberrations were observed only in particular blood indices: a reduced number of thrombosytes in 20.2 % of exposed persons and a tendency towards an increase in the number of CD95-positive lymphocytes may indirectly testify to some concealed injuries in the genome of the cells which representig the offspring of the pool of hematopoietic stem cells that had incurred damages during the period of maximum radiation exposures. No changes were observed in the indices characterizing the functional status of the immune cells and the components of the oxidant stress: the level of oxidants (malonedialdehyde (MDA), endogenous nitrite), and the principal enzyme of the antioxidant protection copper-zinc superoxide dismutase (Cu/Zn SOD) were at the level of equal-age control.

Key words: chronic radiation exposure, peripheral blood, cellular homeostasis, immune system, lipid peroxidation, Soth Urals, population

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For citation: Varfolomeyeva TA, Akleyev AA, Mandrykina AS. The Characteristics of Homeostasis in Individuals Chronically Exposed to Radiation in the South Urals at Late Time after Exposure. Medical Radiology and Radiation Safety. 2016;61(2):39-45. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety, 2016. Vol. 61. No. 2. P. 46-52

DIAGNOSTIC RADIOLODGY

N.V. Khabarina, E.V. Esin

Sonographic Syndromes of Osteochondral Changes of Medium and Small Joints of the Extremities with the Main Types of Arthropathy

Postgraduated Professional Education Institute of A.I. Burnasyan Federal Medical Biophisical Center, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To determine the typical sonographic osteochondral manifestations of rheumatoid (ReA), reactive, gouty arthritis, osteoarthritis (OA), joint syndrome in systemic lupus erythematosus (SLE) and systemic sclerosis (SSc), psoriatic arthropathy (PsA) of the early pathological process, trace its dynamics.

Material and methods: Arthrosonography was made for 540 patients with articular syndrome in the expert class machines. The basic structure of the ultrasonic symptoms of hyaline cartilage and underlying bone, their changes are specific for each type of nosology.

Results: The Change in joint cartilage plates installed in 75.4 % of cases. Echographic pattern of pathology consisted of varying the thickness of the cartilage disk, its echogenicity, texture, contour, presence or absence of additional education in the projection of hyaline tissue. The lack of pathology of the articular cartilage was observed in patients with ReA acute course (n = 70), the debut of gout (n = 8), patients with a short period of the disease SLE, SSc and PsA (n = 19, 16, 69 respectively), in OA young people with the period of the disease is not more than 2 years (n = 52). Bone changes were presented in two versions: as a symptom of hardening layer subchondral bone (9.9 %), symptoms of marginal bone growths (5.2 %). The sensitivity of ultrasound as a whole was 84.4 %, specificity - 83.1 %, accuracy - 83.8 %.

Conclusions: An analysis of the dynamics of the ultrasound picture in rheumatoid and reactive arthritis, osteoarthritis, gout, psoriatic arthropathy and articular syndrome in systemic lupus erythematosus and systemic sclerosis was a direct correlation between the activity of the pathological process, the duration of the disease, its stage of radiological and ultrasound appearances. Erozirovanie articular cartilage may identify within 2.8 months after the occurrence of a destructive arthritis, degenerative changes and microcrystalline inclusions in the thickness of cartilage - after 6.1 months.

Key words: arthropathy, cartilage, bone structure of the joint, ultrasound diagnostics

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For citation: Khabarina NV, Esin EV. Sonographic Syndromes of Osteochondral Changes of Medium and Small Joints of the Extremities with the Main Types of Arthropathy. Medical Radiology and Radiation Safety. 2016;61(2):46-52. Russian.

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Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 2. P. 30-38

RADIATION MEDICINE

Lyaginskya1, I.M. Petoyan1, V.A. Osipov1, A.P. Ermalitskiy1, S.M. Kiselev1, S.V. Akhromeev1, O.E. Kim2

State of Health of the Population Living in the Vicinity of the Enterprise for Radioactive Waste Management, FEC DalRAO

1. A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Medical Health Unit No.100 of FMBA, CTF Fokino, Primorsky Krai, Russia

ABSTRACT

Purpose: To study the state of health of the population of the town Fokino, living in the vicinity of the plant for the radiation waste management in the town Fokino.

Material and methods: A study of people’s state of health, including health assessment of adults, children and evaluation of reproductive health was carries out in the framework of radiationhygienic monitoring. to obtain the necessary information and estimations of the indices of health were used current forms of medical statistics: 7, 12, 19, 30, 31 and 32. All obtained materials were evaluated from the perspective of the available published average data to of the Russian Federation and Far-Eastern federal region in 2007-2011. Basic research was carried out during 2009-2013.

Conclusion: Analysis of the obtained data about state of the health of the population of the town Fokino, living in the vicinity of the plant for the radiation waste management in 2009-2013, showed that health conditions of the population according to the basic indicator (health assessment of adults, children and evaluation of reproductive health) corresponds to the average indicator of center regions of the Russian Federation.

Key words: population health, mortality, morbidity, reproductive health

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For citation: Lyaginskya АМ, Petoyan IM, Osipov VA, Ermalitskiy AP, Kiselev SM, Akhromeev SV, Kim OE. State of Health of the Population Living in the Vicinity of the Enterprise for Radioactive Waste Management, FEC DalRAO. Medical Radiology and Radiation Safety. 2016;61(2):30-8. Russian.

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  1. 2016-2-Vainson-eng
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