SCIENTIFIC AND INFORMATION-ANALYTICAL MAGAZINE

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety. 2016. Vol. 61, No. 5. P. 54-58

DIAGNOSTIC RADIOLDGY

A.D. Ryzhkov1, S.V. Shiryaev1, G.N. Machak2, N.V. Kochergina1, Ya.A. Shchipakhina1, A.S. Krylov1, A.S. Nered1

SPECT/CT in Treatment Monitoring of Bone Metastases of Osteosarcoma with Ultrasound Thermal Ablation Method

1. N.N. Blokhin Russian Cancer Research Center, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. N.N. Priorov Central Research Institute of Traumatology and Orthopaedics, Moscow, Russia

ABSTRACT

Purpose: To demonstrate the diagnostic capabilities to control effects of HIFU treatment in patient with osteosarcoma bone metastases by SPECT-CT method.

Material and methods: SPECT/CT treatment monitoring of the patient with bone metastases of osteosarcoma after ultrasound ablation.

Results: Metastases were detected in the SPECT/CT-pictures. The dynamic observation during the treatment was carried. The effect of the treatment caused by thermoablative manifests in the early stages (observed after 1 month). The effect of the treatment is the lack of accumulation-seeking radiopharmaceutical labeled with 99mTc in the treatment area.

Conclusion: SPECT/CT study is a demonstrative method for early determination of pathological metabolism degree at bone metastases of osteosarcoma after HIFU. SPECT/CT is an effective method of treatment monitoring of bone metastases with use of HIFU therapies.

Key words: SPECT/CT, HIFU, osteosarcoma bone metastases

REFERENSES

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For citation: Ryzhkov AD, Shiryaev SV, Machak GN, Kochergina NV, Shchipakhina YaA, Krylov AS, Nered AS. SPECT/CT in Treatment Monitoring of Bone Metastases of Osteosarcoma with Ultrasound Thermal Ablation Method Medical Radiology and Radiation Safety. 2016;61(5):54-8. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 5. P. 48-53

DIAGNOSTIC RADIOLDGY

A.S. Krylov, A.D. Ryzhkov, Ya.A. Shchipakhina, M.O. Goncharov

99mTc-MIBI Perfusion Scintigraphy and Dynamic Contrast Enhanced Magnetic Resonance Imaging in the Diagnosis of Soft Tissue Sarcomas

N.N. Blokhin Russian Cancer Research Center, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To determine the ability of 99mTc-MIBI perfusion scintigraphy in the diagnosis of soft tissue sarcomas.

Material and methods: The study included 34 patients with primary soft tissue sarcomas. The methodology 99mTc-MIBI perfusion scintigraphy was developed and implemented. Comparison method is dynamic contrast enhanced magnetic resonance imaging (MRI).

Results: 47 paired relative studies were performed to determine tumor’s perfusion.

Conclusion: 1) The method of perfusion scintigraphy with 99mTc-MIBI in the diagnosis of soft tissue sarcomas was developed. 2) The methods of perfusion scintigraphy with 99mTc-MIBI and MRI with dynamic contrast have similar diagnostic capabilities in determining the level of perfusion of soft tissue sarcomas and may be used interchangeably.

Key words: soft tissues sarcomas, 99mTc-MIBI perfusion scintigraphy, dynamic contrast-enhanced MRI

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For citation: Krylov AS, Ryzhkov AD, Shchipakhina YaA, Goncharov MO. 99mTc-MIBI Perfusion Scintigraphy and Dynamic Contrast Enhanced Magnetic Resonance Imaging in the Diagnosis of Soft Tissue Sarcomas. Medical Radiology and Radiation Safety. 2016;61(5):48-53. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety, 2016, Vol. 61. No. 5. P. 27-41

RADIATION EPIDEMIOLOGY

A.N. Koterov, L.N. Ushenkova, A.P. Biryukov, A.S. Samoilov

RET/PTC GENE REARRANGEMENTS FREQUENCY IN PAPILLARY THYROID CARCINOMA WORLDWIDE DEPENDING ON TIME AFTER CHERNOBYL NUCLEAR POWER PLANT ACCIDENT (POOLED-ANALYSIS). POSSIBLE CONTRIBUTION OF FACTORS OF DIAGNOSIS, ‘AGGRESSIVE SURGERY’, RADIATION, AND AGE

A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Results of pooled-analysis of primary data in the database formed from molecular epidemiological sources on RET/PTC gene rearrangements frequency in papillary thyroid carcinoma developed spontaneously and after Chernobyl nuclear power plant accident showed declined chronological trends for RET/PTC1, RET/PTC3 and RET/PTC after the incident separately for cohorts from Europe, USA + Canada and the Asia-Pacific region have been demonstrated. The above trend for RET/PTC3 and RET/PTC in total was similar to trends observed in carcinomas of Chernobyl etiology (Belarus, Russia and Ukraine), although there was no apparent time dependence for RET/PTC1 level in this case. Observed trends could not be connected to any chronological changes in the degree of carcinoma differentiation or age factor for tumor. As chronological changes of RET/PTC frequency in carcinomas in different continents and regions can not be explained by the radiation factor of the Chernobyl accident, it was concluded about the predominant contribution of the ‘human factor’ associated with ‘overestimation’ and ‘overdiagnosis’ of early forms of thyroid tumors in connection with increased vigilance after the Chernobyl accident. Apparently, these factors, along with improvement of instrumental methods at that time, coupled with the ‘aggressive surgery’, took place worldwide resulting in detection of early forms of the occult carcinomas and microcarcinomas. The frequency of RET/PTC in such tumors is higher than in conventional tumors. The frequence of these subjective factors is likely to decrease with time from the date of the Chernobyl accident.

Key words: pooled-analysis, RET/PTC gene rearrangements, papillary thyroid carcinoma, the time after the Chernobyl accident, overestimation

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For citation: Koterov AN, Ushenkova LN, Biryukov AP, Samoilov AS. RET/PTC Gene Rearrangements Frequency in Papillary Thyroid Carcinoma Worldwide Depending on Time after Chernobyl Nuclear Power Plant Accident (Pooled-Analysis). Possible Contribution of Factors of Diagnosis, 'Aggressive Surgery', Radiation, and Age. Medical Radiology and Radiation Safety. 2016;61(5):27-41.

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Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 5. P. 42-47

DIAGNOSTIC RADIOLDGY

N.S. Vorotuntceva, L.G. Nikulshina-Zhikina

The Ultrasonic Diagnostic of Perinatal Neck Injury and Its Consequenses as the Alternative to the Radiological Examination

Kursk State medical university, Kursk, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To reduce radiation exposure to infants of different age groups one must improve radiodiagnosis of perinatal neck injury and its effects.

Material and methods: 679 children in the age of from 7 days to 6 years receiving treatment in the neonatal and premature infants’ pathology unit, psychoneurological unit of children’s hospitals were examined. (X-ray and ultrasonic) examination was carried out. APOLLO X-ray diagnostic complex was used. Radiographs were taken by the standard technique. Ultrasonography of the neck was made on GE Lodgic Expert and ALOKA Prosound a6 ultrasonic scanners with use of the curved and linear transducers of the frequency from 2.9 to 7.5 MHz by our offered technique. Statistical data processing was carried out with use of Statistica 6.0 program.

Results: To reduce radiation exposure to infants of different age groups we suggested the ultrasonic examination technique of children with perinatal neck injury and later one. Comparison of radiological and ultrasonic examination methods in terms of diagnosis of perinatal neck injury and its effects on children of different age groups has been displayed. The diagnosed radiological and ultrasonic symptoms of perinatal children’s groups have been calculated. As the alternative to the radiological examination of the cervical spine, for reducing the radiation exposure to infantile contingent we have proposed the ultrasonic examination technique, intended for diagnosis of perinatal neck injury and its effects in neonatals and children of early and pre-school age.

Conclusions: 1. Functional ultrasonic neck examination of infants, children of early and pre-school age, including estimation of the clavisternomastoid muscles and other soft tissues improves the diagnosis of spinal perinatal injury and its effects. 2. Radiodiagnosis of perinatal neck injury of neonatal and infants of early age should be based on the ultrasonic examination. 3. The neck radiography in the frontal and lateral projections has the priority in the pathology diagnosis of children of pre-school age. However, functional X-ray examinations must be replaced by similar ultrasonic ones.

Key words: birth injury, X-ray diagnostics, ultrasonography, birth spinal injury sequelae, radiological protection, ionizing radiation

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For citation: Vorotuntceva NS, Nikulshina-Zhikina LG.The Ultrasonic Diagnostic Method of Perinatal Neck Injury and Its Consequenses as the Alternative to the Radiological Examination. Medical Radiology and Radiation Safety. 2016;61(5):42-7. Russian.

PDF (RUS) Full-text article (in Russian)

Medical Radiology and Radiation Safety, 2016, Vol. 61. No. 5. P. 13-26

RADIATION EPIDEMIOLOGY

V. Azizova1, E.S. Grigoryeva1, R. Haylock2, M.V. Bannikova1, M.B. Moseeva1

Risk of Incidence and Mortality from Ischemic Heart Disease in the Cohort of Workers with Chronic Occupational Exposure

1. Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Public Health England, Chilton, UK

ABSTRACT

Purpose: Assessment of incidence and mortality risk from ischemic heart disease (IHD) in relation to radiation (external gamma- and internal alpha-exposure) and non-radiation factors (gender, age, smoking, alcohol consumption, hypertension, increased body mass index).

Material and methods: IHD risk was studied in the cohort of workers of the nuclear enterprise (22377 workers, 25 % - females) with chronic occupational exposure. Relative risks and excess relative risks per unit dose (1 Gray) were calculated based on maximum likelihood using AMFIT module of the EPICURE software. Dose estimates used in analyses were provided by an updated ‘Mayak Worker Dosimetry System-2008’.

Results: A significant linear association of IHD incidence risk with total dose from external gamma-rays was observed after having adjusted for non-radiation factors and dose from internal radiation (ERR/Gy = 0.10; 95 % CI: 0.04, 0.17). No significant association of IHD mortality risk was revealed after having adjusted for non-radiation factors and dose from internal alpha-radiation (ERR/Gy = 0.06; 95 % CI: < 0, 0.15). No association of IHD incidence risk with total absorbed dose from internal alpha-radiation to the liver after having adjusted for non-radiation factors and external gamma-dose (ERR/Gy = 0.02; 95 % CI: n/a, 0,10). Statistically significant linear association of IHD mortality risk with total absorbed dose from internal alpha-radiation to the liver was revealed after having adjusted for non-radiation factors and external gamma-dose (ERR/Gy = 0.21; 95 % CI: 0.01, 0.58).

Conclusion: This study provides strong evidence of the association of the ischemic heart disease incidence risk with external gamma-ray exposure and some evidence of the association of the mortality risk for ischemic heart disease with internal alpha-radiation exposure.

Key words: risk, mortality, incidence, ischemic heart disease, Mayak PA, gamma-ray, alpha-radiation, occupational exposure

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For citation: Azizova TV, Grigoryeva ES, Haylock R, Bannikova MV, Moseeva MB. The Risk of Incidence and Mortality from Ischemic Heart Disease in the Cohort of Workers with Chronic Occupational Exposure. Medical Radiology and Radiation Safety. 2016;61(5):13-26. Russian.

PDF (RUS) Full-text article (in Russian)

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